Alka Khaitan
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View article: Postpandemic Trends and Missed Opportunities in Prevention and Diagnosis of Pediatric HIV
Postpandemic Trends and Missed Opportunities in Prevention and Diagnosis of Pediatric HIV Open
Background: Progress against HIV in the US slowed during the COVID-19 pandemic. Associated impacts for pediatric HIV may be substantial amid pandemic-related exacerbations of health inequities. We assessed pre-/post-pandemic trends in pedi…
View article: NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children
NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children Open
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication of SARS-CoV-2 infection characterized by multiorgan involvement and inflammation. Testing of cellular function ex vivo to understand the aberrant immune respons…
View article: Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)
Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C) Open
Multisystem Inflammatory Syndrome in Children (MIS-C) is a severe complication of SARS-CoV-2 infection characterized by multi-organ involvement and inflammation. Testing of cellular function ex vivo to understand the aberrant immune respon…
View article: Real-world Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents
Real-world Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents Open
Background The efficacy of the BNT162b2 vaccine in pediatrics was assessed by randomized trials before the Omicron variant’s emergence. The long-term durability of vaccine protection in this population during the Omicron period remains lim…
View article: Level and Duration of IgG and Neutralizing Antibodies to SARS-CoV-2 in Children with Symptomatic or Asymptomatic SARS-CoV-2 Infection
Level and Duration of IgG and Neutralizing Antibodies to SARS-CoV-2 in Children with Symptomatic or Asymptomatic SARS-CoV-2 Infection Open
There are conflicting data about level and duration of Abs to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children after symptomatic or asymptomatic infection. In this human population, we enrolled adults and children i…
View article: Level and duration of IgG and neutralizing antibodies to SARS-CoV-2 in children with symptomatic or asymptomatic SARS-CoV-2 infection
Level and duration of IgG and neutralizing antibodies to SARS-CoV-2 in children with symptomatic or asymptomatic SARS-CoV-2 infection Open
Background There are presently conflicting data about level and duration of antibodies to SARS-CoV-2 in children after symptomatic or asymptomatic infection. Methods We enrolled adults and children in a prospective 6-month study in the fol…
View article: Integrase Strand Transfer Inhibitors & Weight Gain in Children with Perinatal HIV
Integrase Strand Transfer Inhibitors & Weight Gain in Children with Perinatal HIV Open
Background: In the past, HIV infection was associated with weight loss due to metabolic wasting. Now with early initiation of antiretroviral therapy (ART) an increasing number of patients are being classified as overweight/ obese both prio…
View article: COVID-19 in Children: A Review and Parallels to Other Hyperinflammatory Syndromes
COVID-19 in Children: A Review and Parallels to Other Hyperinflammatory Syndromes Open
During the COVID-19 pandemic, children have had markedly different clinical presentations and outcomes compared to adults. In the acute phase of infection, younger children are relatively spared the severe consequences reported in adults. …
View article: COVID-19 and Hereditary Spherocytosis: A Recipe for Hemolysis
COVID-19 and Hereditary Spherocytosis: A Recipe for Hemolysis Open
Coronavirus Disease 2019 (COVID-19) is the most devastating pandemic of this century. Little is known about the impact of COVID-19 on children, especially those with underlying conditions. We describe the case of a 4-year-old with heredita…