A. Koné
YOU?
Author Swipe
View article: Une fibrose pulmonaire révélant un syndrome de Gougerot Sjogren
Une fibrose pulmonaire révélant un syndrome de Gougerot Sjogren Open
Le syndrome de Gougerot-Sjögren (SGS) est une connectivite auto-immune fréquemment associée à une atteinte des glandes exocrines, mais pouvant également se révéler par des manifestations systémiques. Nous rapportons le cas d’un patient aya…
View article: Groundwater vulnerability to artisanal gold mining pollution: a modified DRASTIC-GIS framework for Siguiri, Republic of Guinea
Groundwater vulnerability to artisanal gold mining pollution: a modified DRASTIC-GIS framework for Siguiri, Republic of Guinea Open
The uncontrolled expansion of gold mining operations and unplanned urban development has triggered a global groundwater contamination crisis. Nowhere is this more apparent than in Guinea’s Siguiri Prefecture, where artisanal and industrial…
View article: Metabolic and immune consequences of antibiotic related microbiome alterations during first-line tuberculosis treatment in Bamako, Mali
Metabolic and immune consequences of antibiotic related microbiome alterations during first-line tuberculosis treatment in Bamako, Mali Open
Background Individuals with a history of tuberculosis (TB) treatment are at a higher risk of experiencing a recurrent episode of the disease. Previous cross-sectional studies identified a connection between dysbiosis (alterations) in the g…
View article: Atypical Presentation of Autoimmune Polyglandular Syndrome Type II: The Tip of the Iceberg at the Interface between Type 2 and Type 3 Multiple Autoimmune Syndrome
Atypical Presentation of Autoimmune Polyglandular Syndrome Type II: The Tip of the Iceberg at the Interface between Type 2 and Type 3 Multiple Autoimmune Syndrome Open
Background: Autoimmune polyglandular syndrome type 2 is a rare condition characterized by at least two induced autoimmune glandular disorders that always includes Addison's disease, as well as type 1 diabetes mellitus and/or autoimmune thy…
View article: Factors associated with SARS-CoV-2 infection amongst Health Workers in Bamako, Mali: a cohort study from November 2021 to February 2023
Factors associated with SARS-CoV-2 infection amongst Health Workers in Bamako, Mali: a cohort study from November 2021 to February 2023 Open
Background. Health workers (HWs) are at high risk of SARS-CoV-2 infection due to their frontline role and considered as priority group for COVID-19 vaccination. This study aimed to estimate SARS-CoV-2 infection and COVID-19 incidence rates…
View article: Epidemiology of Caustic Esophagitis and Factors Associated with the Severity of Endoscopic Lesions in the City of Bouake in Ivory Coast
Epidemiology of Caustic Esophagitis and Factors Associated with the Severity of Endoscopic Lesions in the City of Bouake in Ivory Coast Open
View article: Factors Associated with the Seroprevalence of Hepatitis B Virus Infection among Military Personnel in the Bouaké Region (Côte d’Ivoire)
Factors Associated with the Seroprevalence of Hepatitis B Virus Infection among Military Personnel in the Bouaké Region (Côte d’Ivoire) Open
View article: Impact of Irritable Bowel Syndrome (IBS) on the Quality of Life of Students at the Faculty of Medical Sciences of Bouake
Impact of Irritable Bowel Syndrome (IBS) on the Quality of Life of Students at the Faculty of Medical Sciences of Bouake Open
View article: Surveillance and agnostic capture sequencing of samples from individuals with rash-associated illness in Mali indicates regional transmission of measles virus from West and Central Africa
Surveillance and agnostic capture sequencing of samples from individuals with rash-associated illness in Mali indicates regional transmission of measles virus from West and Central Africa Open
View article: A multiplexed real‐time PCR assay for simultaneous quantification of human immunodeficiency virus and Hepatitis B virus for low‐and‐middle‐ income countries
A multiplexed real‐time PCR assay for simultaneous quantification of human immunodeficiency virus and Hepatitis B virus for low‐and‐middle‐ income countries Open
Due to shared routes of transmission, including sexual contact and vertical transmission, HIV-HBV co-infection is common, particularly in sub-Saharan Africa. Measurement of viral load (VL), for both HIV and HBV, plays a critical role for d…
View article: Empowering public health: building advanced molecular surveillance in resource-limited settings through collaboration and capacity-building
Empowering public health: building advanced molecular surveillance in resource-limited settings through collaboration and capacity-building Open
The rapid detection and continuous surveillance of infectious diseases are important components of an effective public health response. However, establishing advanced molecular surveillance systems, crucial for monitoring and mitigating pa…
View article: Impact of Anemia on the Determination of Glycated Haemoglobin by High-Performance Liquid Chromatography in Diabetic Patients
Impact of Anemia on the Determination of Glycated Haemoglobin by High-Performance Liquid Chromatography in Diabetic Patients Open
Introduction: Glycated haemoglobin is considered an objective element in monitoring glycaemic control in diabetic patients. High-performance liquid chromatography (HPLC) is the reference method for measuring HbA1c. However, even this metho…
View article: Frequent chlamydia and gonorrhoea but very infrequent syphilis among men who have sex with men using HIV pre-exposure prophylaxis in West Africa
Frequent chlamydia and gonorrhoea but very infrequent syphilis among men who have sex with men using HIV pre-exposure prophylaxis in West Africa Open
Objectives Although oral pre-exposure prophylaxis (PrEP) for HIV is being rolled out in West Africa, data on sexually transmitted infections (STIs) in PrEP users are scarce. We assessed the prevalence, incidence and determinants of bacteri…
View article: A novel de novo variant in the <scp><i>RUNX2</i></scp> gene causes cleidocranial dysplasia in a Malian girl
A novel de novo variant in the <span><i>RUNX2</i></span> gene causes cleidocranial dysplasia in a Malian girl Open
Key Clinical Message Cleidocranial dysplasia (CCD) is a rare genetic skeletal disorder with only few cases reported in Africa, mostly based on clinical and radiological findings. We report the first case in Mali, caused by a novel de novo …
View article: Echocardiographic Aspects of Type 2 Diabetics Patients Hospitalized in the Medicine and Endocrinology Department of the Mali Hospital
Echocardiographic Aspects of Type 2 Diabetics Patients Hospitalized in the Medicine and Endocrinology Department of the Mali Hospital Open
Introduction: Cardiovascular disease is the leading cause of death in diabetics. The objective of our study was to investigate the echocardiographic aspects of type 2 diabetics. Patients and Method: Descriptive and cross-sectional study of…
View article: Interest of non-Invasive Markers (APRI, FIB-4) for Assessing Hepatic Fibrosis in Patients with Chronic Viral Hepatitis B without Cytolysis and with Low Viral Replication
Interest of non-Invasive Markers (APRI, FIB-4) for Assessing Hepatic Fibrosis in Patients with Chronic Viral Hepatitis B without Cytolysis and with Low Viral Replication Open
Background and Objectives: The indication for treatment in HBsAg-positive patients with low viral load and normal transaminases requires an assessment of fibrosis. In resource-limited settings, free hepatic fibrosis evaluation tests can ai…
View article: Quantification of Hepatitis B Virus DNA: Validation of a qPCR Approach to detect Pregnant Women at High Risk to Transmit the Virus in Mali.
Quantification of Hepatitis B Virus DNA: Validation of a qPCR Approach to detect Pregnant Women at High Risk to Transmit the Virus in Mali. Open
This work allowed the local development of a sensitive and efficient qPCR protocol for the detection of samples with CVs elevated (>1000 UI/mL). It will detect pregnant women who need to receive antiviral treatment in order to reduce the r…
View article: Performance of two SARS-CoV-2 rapid antigen detection tests in resource limited settings, the case of Mali
Performance of two SARS-CoV-2 rapid antigen detection tests in resource limited settings, the case of Mali Open
Introduction: While real-time reverse transcription PCR (RT-PCR) is the recommended laboratory method to diagnose severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, its use in resource limited settings can be difficult…
View article: PA-516 Association of HIV and mycobacterial lineage on five-year TB treatment outcomes in Mali
PA-516 Association of HIV and mycobacterial lineage on five-year TB treatment outcomes in Mali Open
Background Factors associated with long-term TB treatment outcomes are not well understood. The aim of our study was to determine the association of mycobacterial lineage and HIV co-infection on mortality and TB recurrence five years after…
View article: Clinico-Biological Aspects of Undernutrition in Diabetic Patients Hospitalized in the Medical Department of the Mali Hospital
Clinico-Biological Aspects of Undernutrition in Diabetic Patients Hospitalized in the Medical Department of the Mali Hospital Open
Introduction: Undernutrition is a frequent and often unrecognized pathology in the hospital environment. Its consequences are significant both medically and financially, as it increases hospital length of stay, morbidity and mortality. The…
View article: Metabolic and Immune Consequences of Antibiotic Related Microbiome Alterations during first-line Tuberculosis Treatment in Bamako, Mali
Metabolic and Immune Consequences of Antibiotic Related Microbiome Alterations during first-line Tuberculosis Treatment in Bamako, Mali Open
Background Tuberculosis (TB) infection is known to lead to the unbalance of the gut microbiota and act synergistically on the decline of the host immune response, when untreated. Moreover, previous work has found a correlation between dysb…
View article: Hematological Profiles of Patients with Tuberculosis and Nontuberculous Mycobacteria Infections in Bamako, Mali
Hematological Profiles of Patients with Tuberculosis and Nontuberculous Mycobacteria Infections in Bamako, Mali Open
Background: Pulmonary tuberculosis (TB) remains one of the main causes of morbidity and mortality in Mali. Nontuberculous mycobacteria (NTM) infections are very common but are often cofounded with TB because of the similarity of symptoms, …
View article: Ischemic strokes revealing neurosyphilis: Study of six (6) observations at the neurology Department of the University Hospital of Conakry
Ischemic strokes revealing neurosyphilis: Study of six (6) observations at the neurology Department of the University Hospital of Conakry Open
These neurological vascular syndromes consecutive to a cerebral treponematous attack are often the result of a still poorly conducted management of primary and secondary syphilis in our country.
View article: Therapeutic Aspects of Hypertension in Type 2 Diabetics at the National Diabetes Control Centre in Bamako, Mali
Therapeutic Aspects of Hypertension in Type 2 Diabetics at the National Diabetes Control Centre in Bamako, Mali Open
Introduction: African populations, and particularly those living in Mali, are confronted with the emergence of chronic diseases whose treatment and monitoring represent an additional economic problem for them. Previously unknown, these dis…
View article: Issues in the management of patient companions in Hospital : the case of Hospital du Mali
Issues in the management of patient companions in Hospital : the case of Hospital du Mali Open
Résumé L'accompagnement de malade est le fait d’amener un malade à l’hôpital et de rester à son chevet pour l’assister tout au long de son séjour pendant l’hospitalisation. Il s’agit d’un véritable défi sécuritaire dans l…
View article: Serological Analysis of HBsAg and Anti-HCV Antibody in Patients Received at the Mali Hospital Laboratory
Serological Analysis of HBsAg and Anti-HCV Antibody in Patients Received at the Mali Hospital Laboratory Open
Introduction: Viral hepatitis is a public health threat that has long been underestimated. This infectious disease is the seventh cause of death in the world and even ahead of HIV in terms of epidemiological prevalence. Objective: highligh…
View article: Prevalence of HIV-1 Natural Polymorphisms and Integrase-Resistance-Associated Mutations in African Children
Prevalence of HIV-1 Natural Polymorphisms and Integrase-Resistance-Associated Mutations in African Children Open
Integrase inhibitors (INIs) are a potent option for HIV treatment. Limited data exist on INI resistance in West Africa, particularly in children living with HIV/AIDS. We determined the prevalence of integrase gene polymorphisms and the fre…
View article: Dynamics of SARS-CoV-2 variants characterized during different COVID-19 waves in Mali
Dynamics of SARS-CoV-2 variants characterized during different COVID-19 waves in Mali Open
Several SARS-CoV-2 variants were present during the COVID-19 waves in Mali between April and October 2021. The continued emergence of new variants highlights the need to strengthen local real-time sequencing capacity and genomic surveillan…
View article: <i>Mycoplasma genitalium</i> and Antimicrobial Resistance Among a Cohort of West African Men Who Have Sex With Men Using Preexposure Prophylaxis (CohMSM-PrEP ANRS 12369-Expertise France Study)
<i>Mycoplasma genitalium</i> and Antimicrobial Resistance Among a Cohort of West African Men Who Have Sex With Men Using Preexposure Prophylaxis (CohMSM-PrEP ANRS 12369-Expertise France Study) Open
Background Antimicrobial resistance to macrolides and fluoroquinolones in Mycoplasma genitalium (MG) among men who have sex with men (MSM) is worryingly high in high-resource countries. Data in Africa are lacking. We aimed to assess the bu…
View article: The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance Open
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been generated and used to track the pandemic on the contin…