Explanipedia

Гіпонатріємія при серцевій недостатності: частота виявлення, клінічне значення та методи корекції Open

Alexander Parkhomenko, O. I. Irkin, Ya.M. Lutay, A. O. Stepura, D. O. Bilyi , et al. · 2025

Environmental science

Hyponatremia is an electrolyte disturbance defined as a decrease in serum sodium concentration of less than 135 mmol/L and is the most common electrolyte abnormality in hospitalized patients. The reported incidence of hyponatremia varies b…

Multiple organ dysfunction syndrome in the setting of acute cardiac pathology and concomitant COVID-19: the importance of baseline renal dysfunction and systemic inflammation activation Open

D. О. Bilyi, D Khomiakov, A Parkhomenko, Ya.M. Lutay, O Irkin , et al. · 2025

Medicine

Clinical manifestations of COVID-19 range from asymptomatic to severe pneumonia and acute respiratory distress syndrome. At the same time, patients with concomitant cardiovascular disease have a significantly higher risk of adverse events …

Peripartum cardiomyopathy: current state of the problem Open

Ya.M. Lutay · 2024

Medicine Computer science Engineering

Peripartum cardiomyopathy (PCMP) is cardiomyo-pathy with left ventricular systolic dysfunction that develops in late pregnancy or in the first months of postpartum period. Clinical manifestations can vary from mild or moderate to severe sy…

Перипартальна кардіоміопатія: сучасні можливості ведення пацієнток із важкою серцевою недостатністю Open

Ya.M. Lutay, Alexander Parkhomenko, O. I. Irkin, A. V. Nemyrska · 2024

Computer science

Peripartum cardiomyopathy (PCMP) is a cardiomyopathy with impaired LV systolic function that develops in pregnant women or in the first months after childbirth. Clinical manifestations can vary from mild or moderate to severe symptoms of h…

Prognostic impact of ventricular tachycardia/fibrillation timing on cardio-vascular death in STEMI patients: 5 years of follow-up Open

Sergey Kozhukhov, Alexander Parkhomenko, О И Иркин, Ya.M. Lutay, Nataliia Dovganych · 2023

Medicine

Objectives Ventricular tachycardia (VT) and ventricular fibrillation (VF) are life-threatening arrhythmias that have negative impact on prognosis. This study investigated the relationship between the timing of VT or VF and long-term progno…

No-reflow, acute heart failure and ventricular fibrillation are more common in STEMI patients in wartime conditions Open

Ya.M. Lutay, Alexander Parkhomenko, О И Иркин, O. V. Shumakov, O Skarzhenskyi , et al. · 2023

Medicine

Stress and logistical problems during the wartime can change the course of STEMI and contribute to the development of in-hospital complications. The aim of our work was to analyze in-hospital complications in STEMI pts admitted during the …

Impact of quercetin in patients with myocardial infarction. A multicenter, randomized, and open-label pilot study Open

Sergey Kozhukhov, Alexander Parkhomenko, Ya.M. Lutay, Nataliia Dovganych · 2023

Medicine Chemistry

Our pilot study is the first to demonstrate novel insight into ischemia/reperfusion damage in STEMI patients. The addition of quercetin to standard STEMI therapy limits infarct size and prevents intramyocardial hemorrhage after the first a…

Experience in the emergency cardiology department in wartime conditions Open

Ya.M. Lutay, A Parkhomenko, O Irkin, O Skarzhevskyi, O Shumakov , et al. · 2023

Medicine

Funding Acknowledgements Type of funding sources: None. Physical and psycho-emotional stress during the war can provoke an aggravation of cardiovascular pathology and contribute to the development of in-hospital complications. The aim of o…

In-hospital mortality analysis in patients with acute cardiovascular pathology and co-infection with COVID-19: a registry of one site Open

Ya.M. Lutay, D Khomiakov, O Irkin, A Stepura, D Bilyi , et al. · 2023

Medicine Engineering

Funding Acknowledgements Type of funding sources: None. Patients with cardiovascular pathology have a significantly higher risk of adverse events and death when complicated by concomitant COVID-19. The aim of this study was to analyze in-h…

Acute kidney injury is a risk factor for in-hospital mortality in patients with acute cardiovascular pathology and concomitant COVID-19 Open

Ya.M. Lutay, A Parkhomenko, D Khomiakov · 2023

Medicine Engineering

Funding Acknowledgements Type of funding sources: None. Although respiratory failure and hypoxemia are the main manifestations of COVID-19, many patients also experience worsening kidney function. Hemodynamic disorders in patients with acu…

Аналіз перебігу госпітального періоду захворювання в пацієнтів з невідкладною серцево-судинною патологією та супутньою інфекцією СOVID-19: реєстр одного центру Open

Ya.M. Lutay, О. M. Parkhomenko, D. V. Khomyakov, O. I. Irkin, S. P. Kushnir , et al. · 2023

Medicine Engineering

The aim – to analyze in-hospital mortality in pts with acute cardiovascular pathology (ACP) and a co-infection with COVID-19.Materials and methods. 139 pts with ACP who were diagnosed with COVID-19 were examined. 69 (49.6 %) pts had ACS (4…

Ten-year prognostic impact of acute heart failure in STEMI patients: a prospective cohort study Open

Sergey Kozhukhov, Alexander Parkhomenko, О И Иркин, Ya.M. Lutay, Nataliia Dovganych · 2022

Medicine

Background Cardio-vascular death (CVD) in patients with acute myocardial infarction (AMI) significantly decreased due to reperfusion and advances in pharmacotherapy. Acute heart failure (AHF) remains a common and unfavorable AMI-related co…

Клініко-демографічні характеристики, ведення пацієнтів із цукровим діабетом 2-го типу та судинними ускладненнями: аналіз української когорти реєстру DISCOVER Global Registry Open

О. M. Parkhomenko, Boris Mankovsky, М.V. Vlasenkо, Л.К. Соколова, Ya.M. Lutay , et al. · 2022

Medicine

The aim – to describe baseline data of the Ukraine cohort of DISCOVER Global Registry (DGR) with real-world insights on current treatment practices, complications, and associated clinical outcomes in people with type 2 diabetes mellitus (T…

Cardioprotective strategy in ST-elevation acute myocardial infarction patients after reperfusion with percutaneous coronary intervention Open

Sergey Kozhukhov, Alexander Parkhomenko, Ya.M. Lutay, Ye. B. Yershova · 2020

Medicine

Objectives Reperfusion may cause no-reflow phenomenon. Both microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH) have been recognized as poor prognostic factors in myocardial infarction (MI) patients. The aim of the study w…

Тромбоз коронарных артерий у пациента с миокардитом Open

О. M. Parkhomenko, Ya.M. Lutay, О. И. Иркин, A. O. Stepura, М. Yu. Sokolov , et al. · 2020

Materials science

The article presents the case of the development of acute thrombosis of two coronary arteries in a 35-year-old patient without atherosclerotic lesion of the heart vessels according to optical coherence tomography. Acute myocardial infarcti…

Вплив ранньої ліпідознижувальної терапії різної інтенсивності на функцію ендотелію у хворих з гострим інфарктом міокарда з елевацією сегмента ST Open

О. M. Parkhomenko, A. O. Stepura, Ya.M. Lutay, О. И. Иркин, D. О. Bilyi · 2020

Medicine

The aim – to evaluate the effect of different hypolipidemic therapy on changes in endothelial function in patients with acute myocardial infarction with ST segment elevation (STEMI).Materials and methods. The study enrolled 135 patients wi…

Гострий інфаркт міокарда в осіб молодого віку: особливості патогенезу, перебігу хвороби і обґрунтування стратегії запобігання ускладненням Open

О. M. Parkhomenko, Ya.M. Lutay, О. И. Иркин, D. О. Bilyi, A. O. Stepura , et al. · 2019

Medicine

We retrospectively and prospectively studied 835 patients with acute myocardial infarction (AMI) under the age of 45 and older. Depending on age, patients were divided into two groups: < 45 years and ≥ 45 years. In 189 patients under 45 ye…

Особливості лабораторно-діагностичних показників у хворих різних вікових груп з гострим коронарним синдромом з елевацією сегмента ST Open

О. M. Parkhomenko, Ya.M. Lutay, D. О. Bilyi, О. И. Иркин, A. O. Stepura , et al. · 2019

Medicine

The aim – to find out the features of laboratory diagnostic indicators in patients of different age groups with ST-elevation acute coronary syndrome.Materials and methods. Were analyzed the data of 835 patients admitted to the emergency de…

Клініко-анамнестична характеристика та перебіг госпітального періоду захворювання у хворих молодого віку з гострим коронарним синдромом з елевацією сегмента ST Open

О. M. Parkhomenko, Ya.M. Lutay, O. I. Irkin, D. О. Bilyi, A. O. Stepura , et al. · 2018

Medicine

The aim – to compare the clinical, anamnestic characteristics and course of in-hospital period in patients of different age groups with ST-elevation acute coronary syndrome. Material and methods. Were analyzed the data of 835 patients with…

Острый коронарный синдром без стойкой элевации сегмента ST на электрокардиограмме: клинико-анамнестические факторы неблагоприятного прогноза госпитального периода Open

N. V. Dovgan, О. M. Parkhomenko, Ya.M. Lutay · 2018

Medicine

The aim – to study the risk factors of an unfavorable prognosis and identify patients groups with high risk of complications after acute coronary syndrome (ACS). Material and methods. A total of 490 patients (pts) hospitalized with ACS wit…

Markers of Poor Prognosis in Non-ST Segment Elevation Acute Coronary Syndromes Without Revascularization: A 3-Year Survival Analysis Open

Alexander Parkhomenko, Natalia Dovgan, Ya.M. Lutay, Sergey Kozhukhov · 2018

Medicine

Introduction: The non-ST elevation acute coronary syndrome (NSTE-ACS) account for more than 50% of the total number of patients with ACS. The mortality rates after NSTEMI are not significantly different when compared with patients with ST-…

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