Arya M. Sharma
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View article: Mechanistic insights into microbiome-dependent and personalized responses to dietary fibre in a randomized controlled trial
Mechanistic insights into microbiome-dependent and personalized responses to dietary fibre in a randomized controlled trial Open
Dietary fiber supplementation can reduce cardiometabolic risk, but its effective use is limited by incomplete understanding of fibre-microbiome interactions and highly individualized responses. We tested acacia gum (AG; fermentable fibre),…
View article: “Super-Responders” to Liraglutide Monotherapy and the Growing Evidence of Efficacy of GLP-1 Analogues in Obesity Management: A Longitudinal Prospective Cohort Study
“Super-Responders” to Liraglutide Monotherapy and the Growing Evidence of Efficacy of GLP-1 Analogues in Obesity Management: A Longitudinal Prospective Cohort Study Open
Aims: Individual weight loss results achieved with Glucagon-like Peptide-1 receptor agonists (GLP-1RA) vary significantly. Our aim was to describe the characteristics of patients with obesity who achieved ≥ 20% total weight loss (TWL) on l…
View article: Coproducing COVID‐19 Health Information Resources: A Participatory Study With Older Adults From Minoritised Ethnic Communities in the UK
Coproducing COVID‐19 Health Information Resources: A Participatory Study With Older Adults From Minoritised Ethnic Communities in the UK Open
Background Minoritised ethnic communities in the UK experience disproportionate levels of morbidity and mortality compared to their Caucasian counterparts. This disparity was magnified during the COVID‐19 crisis, particularly amongst older…
View article: Stress and Coping Among Undergraduate Students: A Mixed-Methods Exploration
Stress and Coping Among Undergraduate Students: A Mixed-Methods Exploration Open
Stress is the state of being worried or tensed caused by difficult and unwanted situations. It is body’s involuntary responses to cope up threat. Every people in the world experience stress at a one point of time but the level of stress ma…
View article: A Robust Framework for Heart Rate Estimation from Facial Video Signals Using Signal Enhancement Techniques
A Robust Framework for Heart Rate Estimation from Facial Video Signals Using Signal Enhancement Techniques Open
The demand for non-contact, unobtrusive methods of physiological monitoring has grown significantly with the expansion of telehealth and remote diagnostics. This paper presents a novel technique for estimating heart rate using standard RGB…
View article: Heart Rate Estimation from Remote Photoplethysmography Signal
Heart Rate Estimation from Remote Photoplethysmography Signal Open
Remote photoplethysmography (rPPG) enables noncontact heart rate estimation from facial videos by analyzing subtle color changes correlated with blood volume pulses. However, rPPG signals are often contaminated with motion artifacts, illum…
View article: Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials
Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials Open
Objective To assess the effect of intermittent fasting diets, with continuous energy restriction or unrestricted (ad-libitum) diets on intermediate cardiometabolic outcomes from randomised clinical trials. Design Systematic review and netw…
View article: Differences between Type 2 Diabetes Mellitus and Obesity Management: Medical, Social, and Public Health Perspectives
Differences between Type 2 Diabetes Mellitus and Obesity Management: Medical, Social, and Public Health Perspectives Open
Obesity and type 2 diabetes mellitus (T2DM) are among the most urgent global public health challenges, yet differ markedly in recognition and management across medical, social, infrastructure, and policy domains. T2DM is supported by clear…
View article: Missing the Target: A Scoping Review of the Use of Percent Weight Loss for Obesity Management
Missing the Target: A Scoping Review of the Use of Percent Weight Loss for Obesity Management Open
Introduction To co‐create comprehensive targets for obesity management, we need to understand the genesis and current use of percent weight loss targets in research. The goals of our scoping review are to (1) synthesize the literature on p…
View article: Metabolic profile of healthy, normal-weight adults with low satiety responsiveness
Metabolic profile of healthy, normal-weight adults with low satiety responsiveness Open
The aim of this study was to characterize the metabolic profile of healthy, normal-weight adults presenting with low satiety responsiveness. Individuals were categorized with low or high satiety responsiveness (LSR and HSR, respectively) b…
View article: Determinants of adherence to obesity medication: A narrative review
Determinants of adherence to obesity medication: A narrative review Open
Summary The increasing prevalence of obesity, complex nature of this chronic disease, and risks of developing obesity‐related comorbidities outline the need for sustainable and effective management for people living with obesity. In additi…
View article: Effect of semaglutide 2.4 mg on physical functioning and weight‐ and health‐related quality of life in adults with overweight or obesity: Patient‐reported outcomes from the <scp>STEP</scp> 1–4 trials
Effect of semaglutide 2.4 mg on physical functioning and weight‐ and health‐related quality of life in adults with overweight or obesity: Patient‐reported outcomes from the <span>STEP</span> 1–4 trials Open
Aims To summarize the effects of semaglutide 2.4 mg on weight‐related quality of life (WRQOL) and health‐related quality of life (HRQOL), focusing on the confirmatory secondary endpoint of physical functioning. Materials and Methods The ST…
View article: Patterns of individual compliance with anthelmintic treatment for soil-transmitted helminth infections in southern Ethiopia over six rounds of community-wide mass drug administration
Patterns of individual compliance with anthelmintic treatment for soil-transmitted helminth infections in southern Ethiopia over six rounds of community-wide mass drug administration Open
Background The mainstay of soil-transmitted helminth (STH) control is repeated mass drug administration (MDA) of anthelmintics to endemic populations. Individual longitudinal compliance treatment patterns are important for identifying pock…
View article: Impact of a Powdered Meal Replacement on Metabolism and Gut Microbiota (PREMIUM) in individuals with excessive body weight: a study protocol for a randomised controlled trial
Impact of a Powdered Meal Replacement on Metabolism and Gut Microbiota (PREMIUM) in individuals with excessive body weight: a study protocol for a randomised controlled trial Open
Introduction Excess body weight is associated with a state of low-grade chronic inflammation and alterations of the gut microbiome. Powdered meal replacements (PMR) have been shown to be an effective strategy for weight management; however…
View article: Hyperbaric oxygen therapy a boon for complex post traumatic wounds
Hyperbaric oxygen therapy a boon for complex post traumatic wounds Open
Post-traumatic wounds especially after run over accidents are difficult to manage. The vascularity and regenerative potential of the tissues is severely compromised. Surgical intervention is of limited value. A conservative approach with c…