Mohamed A. Farag
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View article: Unveiling crucifer metabolomes via UPLC-HRMS/MS and chemometric analysis of edible and non-edible varieties
Unveiling crucifer metabolomes via UPLC-HRMS/MS and chemometric analysis of edible and non-edible varieties Open
Cruciferous green vegetables are considered as one of the most important consumed vegetables world-wide owing to their rich nutritive value, characteristic taste as well as health benefits. Cruciferous vegetables are rich in a myriad of bi…
View article: NMR fingerprinting in apricot (Prunus Armeniaca L.) kernels and fruits concerning its different cultivars and soil type as analyzed using chemometrics
NMR fingerprinting in apricot (Prunus Armeniaca L.) kernels and fruits concerning its different cultivars and soil type as analyzed using chemometrics Open
View article: Pomegranate peel extract alleviates diabetic retinopathy by suppressing the PI3K/AKT/HIF-1α/VEGF pathway and gut microbiota modulation
Pomegranate peel extract alleviates diabetic retinopathy by suppressing the PI3K/AKT/HIF-1α/VEGF pathway and gut microbiota modulation Open
PPE exhibited therapeutic effects in DR by directly alleviating retinal damage via the suppression of oxidative stress and inhibition of PI3K/AKT/HIF-1α/VEGF pathway, as well as indirectly modulating gut microbiota. These findings suggeste…
View article: Nitrogenous flavonoid derivatives production by reacting with amino acids
Nitrogenous flavonoid derivatives production by reacting with amino acids Open
View article: An Efficient Approach to Detecting a Copy-Move Forgery in Videos
An Efficient Approach to Detecting a Copy-Move Forgery in Videos Open
In the past years, the advancement in editing technologies, especially multimedia, has contributed to increased image and video modification use. However, object-based video tampering, such as including or excluding objects in the video fr…
View article: Hydroxyl Groups on the B Ring of Flavonols Significantly Impact the Energy and Lipid Metabolism in Mice: A Biochemical and Gut Microbiota Approach
Hydroxyl Groups on the B Ring of Flavonols Significantly Impact the Energy and Lipid Metabolism in Mice: A Biochemical and Gut Microbiota Approach Open
In this study, quercetin, myricetin, kaempferol, and morin were compared in context to their ameliorative effects on lipid disorders in high‐fat dietary mice. In both normal and high‐fat dietary mice, flavonol intervention promoted energy …
View article: Tannin in foods: Classification, Dietary Sources, and Processing Strategies to Minimize Anti-Nutrient Effects
Tannin in foods: Classification, Dietary Sources, and Processing Strategies to Minimize Anti-Nutrient Effects Open
Anti-nutrients are naturally occurring compounds that negatively affect nutrient intake, absorption, and utilisation, ultimately impairing human and animal growth and development. These include various phytochemicals such as tannins, cyano…
View article: Gas Chromatography Mass Spectrometry Profiling of Volatiles from 5 Major Apiaceous Aerial Parts via Headspace solid phase microextraction Compared to Essential Oil, and In Context of Anti-tuberculosis Effect
Gas Chromatography Mass Spectrometry Profiling of Volatiles from 5 Major Apiaceous Aerial Parts via Headspace solid phase microextraction Compared to Essential Oil, and In Context of Anti-tuberculosis Effect Open
Objective Green leafy vegetables from the Apiaceae family are widely consumed due to their distinctive aroma, flavour, and recognized medicinal properties. While the flavour composition of dried Apiaceae fruits has been extensively studied…
View article: Gas chromatography-mass spectrometry and Fourier-transform infrared spectroscopy coupled to chemometrics for metabolome analysis of different milk types in the light of green analytical chemistry
Gas chromatography-mass spectrometry and Fourier-transform infrared spectroscopy coupled to chemometrics for metabolome analysis of different milk types in the light of green analytical chemistry Open
Background Milk is an important dietary source for a healthy and balanced diet, owing to its rich content of proteins, fats, sugars, vitamins, and minerals. Due to the importance of milk macronutrient content for consumers’ preferences, a …
View article: Glucosinolates and Their Biotransformation: Metabolism, Plant Roles, and Human Health
Glucosinolates and Their Biotransformation: Metabolism, Plant Roles, and Human Health Open
View article: Integrated metabolomic profiling of olive oil, olive mill wastewater, and pomace from Egyptian cultivars based on UHPLC-MS/MS and NMR coupled with chemometrics
Integrated metabolomic profiling of olive oil, olive mill wastewater, and pomace from Egyptian cultivars based on UHPLC-MS/MS and NMR coupled with chemometrics Open
Valuable bioactive metabolites were identified in olive oil by-products, supporting their potential use in sustainable, health-promoting applications. "Chemlali black" and "Chemlali green" cvs. are recognized as promising sources for nutra…
View article: Mapping Aroma Distribution of <i>Torreya grandis</i> Tissues: A Multisensory Analytical Approach via GC–E–Nose, HS–SPME–GC–MS, and Olfactometry–MS Techniques
Mapping Aroma Distribution of <i>Torreya grandis</i> Tissues: A Multisensory Analytical Approach via GC–E–Nose, HS–SPME–GC–MS, and Olfactometry–MS Techniques Open
Torreya grandis , an economically important nut tree, exhibits significant tissue‐specific aroma profiles, yet the distribution and sensory contributions of its key aroma‐active components remain unclear. This study employed a multimodal a…
View article: VEGETATIVE PROPAGATION OF INDIAN JUJUBE (Ziziphus mauritiana, LAMK) GROWN IN ISMAILIA REGION
VEGETATIVE PROPAGATION OF INDIAN JUJUBE (Ziziphus mauritiana, LAMK) GROWN IN ISMAILIA REGION Open
View article: INFLUENCE OF DIETARY TURMERIC AND CURCUMIN SUPPLEMENTATION ON THE PRODUCTIVE AND REPRODUCTIVE PERFORMANCE OF GIMMIZAH LAYING HENS
INFLUENCE OF DIETARY TURMERIC AND CURCUMIN SUPPLEMENTATION ON THE PRODUCTIVE AND REPRODUCTIVE PERFORMANCE OF GIMMIZAH LAYING HENS Open
View article: Metabolomics in guava: a comprehensive review of quality, agricultural traits, composition, and nutraceutical applications of Psidium guajava fruits and byproducts
Metabolomics in guava: a comprehensive review of quality, agricultural traits, composition, and nutraceutical applications of Psidium guajava fruits and byproducts Open
Psidium guajava , commonly known as guava, is a vital tree in the Myrtaceae family, valued for its nutrient-rich fruit and diverse medicinal uses. Known as the "Queen of Fruits," guava is recognized for its high vitamin C content and other…
View article: Berry Wax‐Related Research and Biomimetic Technology
Berry Wax‐Related Research and Biomimetic Technology Open
View article: A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects
A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects Open
Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo‐hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering…
View article: Comparative Mass Spectroscopy Profiling of Masala Spices: Unveiling Direct and Remote Antimicrobial Effects of Nonvolatile and Aroma Metabolites via Biochemometric Tools and Molecular Networking
Comparative Mass Spectroscopy Profiling of Masala Spices: Unveiling Direct and Remote Antimicrobial Effects of Nonvolatile and Aroma Metabolites via Biochemometric Tools and Molecular Networking Open
Herbal spices are widely used as food additives not only for their distinct aroma and flavor but rather for their health‐promoting properties. In this study, the chemical profiles of four major masala spices—chaat (CMP), pav‐bhaji (PMP), s…
View article: Mean gestational sac diameter, Embryonic heart rate and CA-125 as prognostic factors for first trimesteric outcome
Mean gestational sac diameter, Embryonic heart rate and CA-125 as prognostic factors for first trimesteric outcome Open
View article: GC-MS based nutritional and aroma profiling of date palm seeds collected from different Egyptian cultivars for valorization purposes
GC-MS based nutritional and aroma profiling of date palm seeds collected from different Egyptian cultivars for valorization purposes Open
Date palm ( Phoenix dactylifera L.) is a globally edible fruit and a traditional dietary component in various cultures. The fruit’s fleshy part is consumed for its nutritional value, while the seeds are discarded or valorized for oil produ…
View article: Microplastics and nanoplastics: fate, transport, and governance from agricultural soil to food webs and humans
Microplastics and nanoplastics: fate, transport, and governance from agricultural soil to food webs and humans Open
Microplastics (MPs) and nanoplastics (NPs) are pervasive contaminants in agricultural soils, raising concerns over their environmental fate, food chain infiltration, and potential human health impacts. This review critically examines their…
View article: In vivo anti-ulceration effect of Pancratium maritimum extract against ethanol-induced rats via NLRP3 inflammasome and HMGB1/TLR4/MYD88/NF-κβ signaling pathways and its extract metabolite profile
In vivo anti-ulceration effect of Pancratium maritimum extract against ethanol-induced rats via NLRP3 inflammasome and HMGB1/TLR4/MYD88/NF-κβ signaling pathways and its extract metabolite profile Open
Background Gastric ulcer is a multifaceted ailment of multiple causes and is chronic warranting the discovery of remedies to alleviate its symptoms and severity. Pancratium maritimum L. is recognized for its several health benefits, althou…
View article: Assessment of Metabolome Variation in Field‐Grown Lettuce in Context to Its Different Types and Soil Types as Analyzed via GC‐MS Analysis and Using of Chemometric Tools
Assessment of Metabolome Variation in Field‐Grown Lettuce in Context to Its Different Types and Soil Types as Analyzed via GC‐MS Analysis and Using of Chemometric Tools Open
Lettuce ( Lactuca sativa L.) is one of the most important ready‐to‐eat vegetables widely consumed worldwide owing to its nutritional and health benefits. A total of 111 peaks were identified via gas chromatography‐mass spectrometry (GC‐MS)…
View article: Anticryptosporidial action mechanisms of Launaea spinosa extracts in Cryptosporidium parvum experimentally infected mice in relation to its UHPLC-MS metabolite profile and biochemometric tools
Anticryptosporidial action mechanisms of Launaea spinosa extracts in Cryptosporidium parvum experimentally infected mice in relation to its UHPLC-MS metabolite profile and biochemometric tools Open
Background Cryptosporidium parvum , a leading cause of diarrhea, is responsible for millions of food and waterborne illnesses in humans and animals worldwide. Launaea spinosa (Asteraceae family) is a common herb found in the desert of the …
View article: Ammoniation of Dietary Flavonoids Containing a Pyrogallol Group With Amino Acids at 37°C
Ammoniation of Dietary Flavonoids Containing a Pyrogallol Group With Amino Acids at 37°C Open
New research shows that flavonoids containing a pyrogallol group in ring B react with amino acids at 37°C, forming ammoniated derivatives and aldehydes. Despite this, studies on these reactions and the activity of the resulting ammoniated …
View article: Amination of Flavonoids Possessing a Pyrogallol Group in Cell Culture Medium at 37°C
Amination of Flavonoids Possessing a Pyrogallol Group in Cell Culture Medium at 37°C Open
A class of flavonoid aminated derivatives that had been consistently overlooked in literature was shown to be formed as artefacts in cell culture medium. In this study, 34 flavonoids from different subclasses were incubated in Dulbecco's m…
View article: Author Correction: Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites
Author Correction: Bifidobacterium animalis Probio-M8 improves sarcopenia physical performance by mitigating creatine restrictions imposed by microbial metabolites Open
View article: A Multiplexed Biosensor Integrated with Controller Board for Standard Addition Voltammetric Signal Analysis of Cardiac Troponin-I
A Multiplexed Biosensor Integrated with Controller Board for Standard Addition Voltammetric Signal Analysis of Cardiac Troponin-I Open
View article: Egcg Alleviates Premature Aging Caused by Excessive Methionine Intake Via the Formation of N-Egcg and Activation of Daf-16/Foxo
Egcg Alleviates Premature Aging Caused by Excessive Methionine Intake Via the Formation of N-Egcg and Activation of Daf-16/Foxo Open
View article: A multifaceted review on extraction optimization, nanoformulation, and chemical modification approaches to enhance the yield, bioavailability, and health effects of xanthones
A multifaceted review on extraction optimization, nanoformulation, and chemical modification approaches to enhance the yield, bioavailability, and health effects of xanthones Open
This review explores optimized extraction, nanoformulation, and chemical modification strategies of natural xanthones to enhance their yield, solubility, bioavailability, and therapeutic potential, particularly in cancer therapy.