Explanipedia

Impact of donor-recipient ethnic matching on survival after lung transplantation in Italy Open

A. Palleschi, Marco Schiavon, Paola Besani, Federico Rea, Daniele Diso , et al. · 2025

Unlocking the potential of uncontrolled DCD in lung transplantation: A review of 2 decades of experience Open

Irene Bello, A. Palleschi, Marcelo Cypel, Eduard Argudo, Alberto Sandiumenge · 2025

Uncontrolled donation after circulatory death (uDCD) represents a promising yet underutilized approach to expanding the lung donor pool amid persistent organ shortages. Since the first successful lung transplantation from a uDCD donor in 2…

Pulmonary function prediction in lung cancer resection candidates: the latest insights Open

Riccardo Orlandi, Sara Degiovanni, Clarissa Uslenghi, Asia Anghinelli, Paola Besana , et al. · 2025

Surgical resection remains the most effective curative option for early-stage nonsmall cell lung cancer (NSCLC) in fit patients. However, many individuals with NSCLC have comorbidities that elevate surgical risks and complicate postoperati…

Editorial: New perspectives in robotic-assisted thoracic surgery (RATS) Open

Davide Tosi, Edoardo Bottoni, A. Palleschi · 2025

Dealing With Antibiotic Prophylaxis in Lung Transplantation in the Era of Multidrug Resistance: The Milano Algorithm Open

Andrea Lombardi, Davide Mangioni, Giulia Renisi, Jacopo Fumagalli, Letizia Corinna Morlacchi , et al. · 2025

MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity Open

Dillon P. Boulton, Connor J. Hughes, Valentina Vaira, Alessandro Del Gobbo, A. Palleschi , et al. · 2024

Metastasis to vital organs remains the leading cause of cancer-related deaths, emphasizing an urgent need for actionable targets in advanced-stage cancer. The role of mitochondrial Rho GTPase 2 (MIRO2) in prostate cancer growth was recentl…

Bilateral Lung Transplantation in Patients With Severe Chest Asymmetry: A Case Series From a Single Center Open

Paolo Mendogni, A. Palleschi, Giacomo Grisorio, Alessandra Mazzucco, Cristina Diotti , et al. · 2024

Suppurative lung diseases leading to end‐stage respiratory failure are typical indications for bilateral lung transplantation (LuTx). Some cases may present severe chest asymmetry because of recurrent infections or previous surgical proced…

Transition from Transbronchial Forceps to Cryobiopsy After Lung Transplantation: A Single-Centre Experience Open

Davide Tosi, Margherita Brivio, Sara Franzi, A. Palleschi, Gianluca Bonitta , et al. · 2024

The gold standard for histological acute cellular rejection diagnosis is transbronchial forceps biopsy (FB), but in recent years, transbronchial cryobiopsy (CB) has been increasingly used. This study aims to compare the diagnostic rate and…

Immunopathology of lung transplantation: from infection to rejection and vice versa Open

I. Righi, Ivan Barone, Lorenzo Rosso, Letizia Corinna Morlacchi, V. Rossetti , et al. · 2024

Lung transplantation offers a lifesaving option for patients with end-stage lung disease, but it is marred by a high risk of post-transplant infections, particularly involving multidrug-resistant bacteria, Cytomegalovirus, and fungal patho…

Diaphragm and Lung Transplantation Open

A. Palleschi, Giovanni Mattioni, Antonella LoMauro, Emilia Privitera, Valeria Musso , et al. · 2024

Mutual interactions between the diaphragm and lung transplantation (LTx) are known to exist. Before LTx, many factors can exert notable impact on the diaphragmatic function, such as the underlying respiratory disease, the comorbidities, an…

Ex Vivo Lung Perfusion (EVLP): An Algorithm Proposal to Identify Acceptable Organs for Transplantation Open

C. Magri, Fabiana Madotto, A. Palleschi, Lorenzo Rosso, Franco Valenza , et al. · 2024

Which extent of surgical resection thoracic surgeons would choose if they were diagnosed with an early-stage lung cancer: a European survey Open

Alessandro Brunelli, Herbert Decaluwé, Michel González, Dominique Gossot, René Horsleben Petersen , et al. · 2024

Dealing with Antibiotic Prophylaxis in Lung Transplantation in the Era of Multi-Drug Resistance: The Milano Algorithm Open

Andrea Lombardi, Davide Mangioni, Giulia Renisi, Jacopo Fumagalli, Letizia Corinna Morlacchi , et al. · 2024

Pneumonectomy for Unilateral Proximal Interruption of Pulmonary Artery: A Case Series from the Literature Open

Giovanni Mattioni, Mario Nosotti, Lorenzo Rosso, A. Palleschi, Davide Tosi , et al. · 2023

Background: Unilateral proximal interruption of the pulmonary artery (UPIPA) is a rare congenital disease, and its optimal management remains undefined in the existing literature. The occasional necessity for pneumonectomy is still support…

Pulmonary Lobectomy for Early-Stage Lung Cancer with Uniportal versus Three-Portal Video-Assisted Thoracic Surgery: Results from a Single-Centre Randomized Clinical Trial Open

Davide Tosi, Alessandra Mazzucco, Valeria Musso, Gianluca Bonitta, Lorenzo Rosso , et al. · 2023

Video-assisted thoracic surgery (VATS) is a consolidated approach; however, there is no consensus on the number of ports leading to less postoperative pain. We compared early postoperative pain after uniportal and three-portal VATS lobecto…

Telemonitoring: An opportunity in cystic fibrosis lung transplant recipients Open

Letizia Corinna Morlacchi, Emilia Privitera, V. Rossetti, Martina Santambrogio, Angela Bellofiore , et al. · 2023

Quantitative CT imaging to predict postoperative pulmonary function in patients undergoing lung resection surgery: pilot study Open

Alessandro Molani, Francesca Pennati, R. Carrinola, A. Palleschi, Andréa Aliverti · 2023

Anatomical segment-counting is the common approach to estimate postoperative lung function in patients candidates for pulmonary lobectomy. However, this method provides a global and theoretical evaluation only. We hypothesize that quantita…

(109) Insights Into the Lung Microenvironment During Chronic Allograft Rejection: The Role of Bal-Evs in Rewiring Respiratory Cells Inflammatory Response Open

V. Vaira, A. Storaci, S. Franzi, M. Pitasi, F. Gentile , et al. · 2023

(907) Lung Transplantation from Uncontrolled Donation after Circulatory Death Donors with Prolonged Ischemic Times. Favourable Outcomes with a Simple Ventilation-Based Preservation Strategy Open

A. Palleschi, V. Musso, D. Tosi, A. Zanella, L. Morlacchi , et al. · 2023

Advances in Lung Transplantation Open

Davide Tosi, A. Palleschi · 2023

Nowadays, lung transplantation is a clinical reality for the treatment of benign end-stage respiratory diseases [...]

A real-world experience of transition to robotic-assisted thoracic surgery (RATS) for lung resections Open

A. Palleschi, Giovanni Mattioni, Paolo Mendogni, Davide Tosi · 2023

Objective We report our experience of transition to robotic-assisted thoracic surgery (RATS) for lung resections with the da Vinci Xi surgical system, exposing short-term results. Materials and methods This is a single-center, retrospectiv…

Lung Transplantation From Controlled and Uncontrolled Donation After Circulatory Death (DCD) Donors With Long Ischemic Times Managed by Simple Normothermic Ventilation and Ex-Vivo Lung Perfusion Assessment Open

A. Palleschi, Alberto Zanella, Giuseppe Citerio, Valeria Musso, Lorenzo Rosso , et al. · 2023

Donation after cardiac death (DCD) donors are still subject of studies. In this prospective cohort trial, we compared outcomes after lung transplantation (LT) of subjects receiving lungs from DCD donors with those of subjects receiving lun…

Approaches and outcomes of Robotic-Assisted Thoracic Surgery (RATS) for lung cancer: a narrative review Open

Giovanni Mattioni, A. Palleschi, Paolo Mendogni, Davide Tosi · 2022

Identification of a new potential plasmatic biomarker panel for the diagnosis of malignant pleural mesothelioma Open

Luca Ferrari, Simona Iodice, Laura Cantone, Barbara Dallari, Laura Dioni , et al. · 2022

Background: Malignant pleural mesothelioma (MPM) is a rare highly aggressive tumor strongly associated with asbestos exposure and characterized by poor prognosis. Currently, diagnosis is based on invasive techniques, thus there is a need o…

Lung Transplant for ARDS after COVID-19: Long-Term Outcomes and Considerations about Detrimental Issues Open

A. Palleschi, Stefania Crotti, Anna Mara Scandroglio, Alfredo Lissoni, Evgeny Fominskiy , et al. · 2022

During the first outbreak of COVID-19 in Italy, based on the only few cases reported from a Chinese centre at the time, we performed lung transplantation in two patients with irreversible acute respiratory distress syndrome (ARDS) after CO…

Correction: Uniportal and three-portal video-assisted thoracic surgery pulmonary lobectomy for early-stage lung cancer (UNIT trial): study protocol of a single-center randomized trial Open

Paolo Mendogni, Alessandra Mazzucco, A. Palleschi, Lorenzo Rosso, I. Righi , et al. · 2022

Lung Transplantation From Donation After Brain Death Donors on Extracorporeal Support Open

A. Palleschi, İlhan İnci, Dirk Van Raemdonck, Jonas Peter Ehrsam, Laurens J. Ceulemans , et al. · 2022

Shortage of lung donors has led transplantation programs to work on new approaches to getting potential donors. In contrast, lung transplant surgeons face the advances in treatments for critically ill patients, including the increased use …

Lung Biomolecular Profile and Function of Grafts from Donors after Cardiocirculatory Death with Prolonged Donor Warm Ischemia Time Open

F. Gori, Jacopo Fumagalli, Caterina Lonati, Andrea Carlin, Patrizia Leonardi , et al. · 2022

The acceptable duration of donor warm ischemia time (DWIT) after cardiocirculatory death (DCD) is still debated. We analyzed the biomolecular profile and function during ex vivo lung perfusion (EVLP) of DCD lungs and their correlation with…

Bilateral Lung Transplantation in Severe Chest Asymmetry: Case Series from a Single Center Open

Lorenzo Rosso, Paolo Mendogni, A. Palleschi, Davide Tosi, I. Righi , et al. · 2022

Telemonitoring: An Opportunity to Improve Multidisciplinary Care in Lung Transplanted Patients Open

V. Rossetti, Martina Santambrogio, Letizia Corinna Morlacchi, Roberto Orlandi, Serena Tammaro , et al. · 2022

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