Anne‐Laure Perraud
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View article: Bcl-2 Suppresses Sarcoplasmic/Endoplasmic Reticulum Ca 2+ -ATPase Expression in Cystic Fibrosis Airways: Role in Oxidant-mediated Cell Death
Bcl-2 Suppresses Sarcoplasmic/Endoplasmic Reticulum Ca 2+ -ATPase Expression in Cystic Fibrosis Airways: Role in Oxidant-mediated Cell Death Open
Rationale: Modulation of the activity of sarcoendoplasmic reticulum calcium ATPase (SERCA) can profoundly affect Ca2+ homeostasis. Although altered calcium homeostasis is a characteristic of cystic fibrosis (CF), the role of SERCA is unkno…
View article: Supplementary Material for: Mice Lacking Fatty Acid-Binding Protein 5 Are Resistant to <b><i>Listeria monocytogenes</i></b>
Supplementary Material for: Mice Lacking Fatty Acid-Binding Protein 5 Are Resistant to <b><i>Listeria monocytogenes</i></b> Open
To investigate the role of fatty acid-binding protein 5 (FABP5) in infectious diseases, FABP5-deficient mice were challenged with Listeria monocytogenes, a facultative intracellular bacterial pathogen. Interestingly, FABP5-deficient animal…
View article: Mice Lacking Fatty Acid-Binding Protein 5 Are Resistant to <b><i>Listeria monocytogenes</i></b>
Mice Lacking Fatty Acid-Binding Protein 5 Are Resistant to <b><i>Listeria monocytogenes</i></b> Open
To investigate the role of fatty acid-binding protein 5 (FABP5) in infectious diseases, FABP5-deficient mice were challenged with Listeria monocytogenes, a facultative intracellular bacterial pathogen. Interestingly, FABP5-deficient animal…
View article: TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice
TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice Open
Objective— TRPM7 (transient receptor potential cation channel, subfamily M, member 7) is a ubiquitously expressed bifunctional protein comprising a transient receptor potential channel segment linked to a cytosolic α-type serine/threonine …
View article: Cigarette smoke inhibits LPS-induced FABP5 expression by preventing c-Jun binding to the FABP5 promoter
Cigarette smoke inhibits LPS-induced FABP5 expression by preventing c-Jun binding to the FABP5 promoter Open
Cigarette smoking is the primary cause of chronic obstructive pulmonary disease (COPD) with repeated and sustained infections linked to disease pathogenesis and exacerbations. The airway epithelium constitutes the first line of host defens…
View article: Signature Channels of Excitability no More: L-Type Channels in Immune Cells
Signature Channels of Excitability no More: L-Type Channels in Immune Cells Open
Although the concept of Ca(2+) as a universal messenger is well established, it was assumed that the regulatory mechanisms of Ca(2+)-signaling were divided along the line of electric excitability. Recent advances in molecular biology and g…