Antonio Rivero
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View article: Intensification with a CCR5 inhibitor at ART initiation Modulates IL-18 and Inflammation-Driven Immune Pathways in People with HIV
Intensification with a CCR5 inhibitor at ART initiation Modulates IL-18 and Inflammation-Driven Immune Pathways in People with HIV Open
Our results suggest that MVC intensification at ART initiation might contribute to reducing IL-18 levels and inflammation-driven immune pathways, providing insights for strategies to mitigate persistent inflammation in PWH.
View article: Hepatitis E virus screening in solid organ transplant recipients: prevalence and implications for implementation, Spain, 2021 to 2023
Hepatitis E virus screening in solid organ transplant recipients: prevalence and implications for implementation, Spain, 2021 to 2023 Open
INTRODUCTION: In solid organ transplant (SOT) recipients, hepatitis E virus (HEV) poses a complex clinical challenge, because there is a risk of developing persistent infection. Current European guidelines recommend the screening of HEV in…
View article: Trends in Hepatitis C Virus Infection Prevalence Among People With HIV in Spain Over 2 Decades (2002–2023)
Trends in Hepatitis C Virus Infection Prevalence Among People With HIV in Spain Over 2 Decades (2002–2023) Open
Background Hepatitis C virus (HCV) has significantly impacted people with human immunodeficiency virus (HIV). Harm reduction programs, changing transmission patterns, and direct-acting antivirals (DAAs) have profoundly altered HIV/HCV coin…
View article: Zoonotic rat hepatitis E virus infection in pigs: farm prevalence and public health relevance
Zoonotic rat hepatitis E virus infection in pigs: farm prevalence and public health relevance Open
Rat hepatitis E virus (ratHEV) is an emerging zoonotic pathogen causing acute and chronic hepatitis, with zoonotic transmission pathways that remain unclear. While rats are its primary reservoir, recent experimental studies revealed that p…
View article: Afamin and Apolipoprotein F Associated With Liver Steatosis From People Living With <scp>HIV</scp>: A Discovery Study
Afamin and Apolipoprotein F Associated With Liver Steatosis From People Living With <span>HIV</span>: A Discovery Study Open
Introduction Liver steatosis (LS) is a condition that is characterised by hepatic fat accumulation unrelated to significant alcohol consumption. This study explored the serum proteomic profile associated with LS in people living with HIV (…
View article: FibroScan-AST Score vs Liver Stiffness for the Prediction of Liver Events After HCV Cure
FibroScan-AST Score vs Liver Stiffness for the Prediction of Liver Events After HCV Cure Open
Background Liver stiffness (LS) predicts liver complication occurrence in patients with hepatitis C virus (HCV) infection after sustained virological response (SVR). The FibroScan-AST (FAST) score, which includes aspartate aminotransferase…
View article: National survey of the rat hepatitis E virus in rodents in Spain, 2022 to 2023
National survey of the rat hepatitis E virus in rodents in Spain, 2022 to 2023 Open
Background Rat hepatitis E virus (ratHEV) is an emerging virus causing acute and chronic hepatitis in humans. Rats are the main natural reservoir of this pathogen. Large-scale studies assessing ratHEV circulation in rodents in Spain are la…
View article: Real-world Effectiveness and Safety of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Comparison With Other Regimens in People With HIV Starting Therapy With AIDS-Defining Conditions: Results From the CoRIS Cohort—The ACTUAS II Study
Real-world Effectiveness and Safety of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Comparison With Other Regimens in People With HIV Starting Therapy With AIDS-Defining Conditions: Results From the CoRIS Cohort—The ACTUAS II Study Open
Background The comparative effectiveness and tolerability of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) has not been sufficiently evaluated in people with AIDS who initiate therapy. Methods The aim of the current study w…
View article: Ambulatory inguinal hernia repair in Portugal - a multicenter prospective cohort study
Ambulatory inguinal hernia repair in Portugal - a multicenter prospective cohort study Open
Ambulatory surgery is the recommended approach for elective inguinal hernia repair for most people. However, the relative use of this procedure in Portugal and its related outcomes are unknown. We aimed to assess complication rates in pati…
View article: Impact of Nonalcoholic Fatty Liver Disease on the Survival of People Living With <scp>HIV</scp>
Impact of Nonalcoholic Fatty Liver Disease on the Survival of People Living With <span>HIV</span> Open
Background Nonalcoholic fatty liver disease (NAFLD) is an increasing concern for people living with HIV (PLWH). However, information on the impact of NAFLD on the prognosis of PLWH is very scarce. Aims To investigate the influence of NAFLD…
View article: Impact of Human Leukocyte Antigen Allele–Killer Cell Immunoglobulin-like Receptor Partners on Sexually Transmitted Human Immunodeficiency Virus Type 1 Infection
Impact of Human Leukocyte Antigen Allele–Killer Cell Immunoglobulin-like Receptor Partners on Sexually Transmitted Human Immunodeficiency Virus Type 1 Infection Open
Human leukocyte antigen (HLA) class I/killer cell immunoglobulin-like receptor (KIR) genotypes influence human immunodeficiency virus type 1 (HIV-1) disease progression and viral load, but their role in primary infection is uncertain. Inco…
View article: Serological and molecular survey of rat hepatitis E virus ( <i>Rocahepevirus ratti</i> ) in drug users
Serological and molecular survey of rat hepatitis E virus ( <i>Rocahepevirus ratti</i> ) in drug users Open
ABSTRACTRat hepatitis E virus (ratHEV) is an emerging cause of acute hepatitis of zoonotic origin. Since seroprevalence studies are scarce, at-risk groups are almost unknown. Because blood-borne infections frequently occur in people with d…
View article: Early Detection of Cancer and Precancerous Lesions in Persons With HIV Through a Comprehensive Cancer Screening Protocol
Early Detection of Cancer and Precancerous Lesions in Persons With HIV Through a Comprehensive Cancer Screening Protocol Open
Background Non-AIDS defining malignancies present a growing challenge for persons with human immunodeficiency virus (HIV, PWH), yet tailored interventions for timely cancer diagnosis are lacking. The Spanish IMPAC-Neo protocol was designed…
View article: Incidence of Diabetes Mellitus and Associated Factors in the Era of Antiretroviral Drugs With a Low Metabolic Toxicity Profile
Incidence of Diabetes Mellitus and Associated Factors in the Era of Antiretroviral Drugs With a Low Metabolic Toxicity Profile Open
Objective The incidence of type 2 diabetes mellitus (T2DM) has risen dramatically. Among people living with HIV (PLHIV), chronic disease (now >15 cases/1000 in the general population worldwide) and long-term exposure to antiretroviral t…
View article: The HIV-1 reservoir landscape in persistent elite controllers and transient elite controllers
The HIV-1 reservoir landscape in persistent elite controllers and transient elite controllers Open
BACKGROUNDPersistent controllers (PCs) maintain antiretroviral-free HIV-1 control indefinitely over time, while transient controllers (TCs) eventually lose virological control. It is essential to characterize the quality of the HIV reservo…
View article: Comparison of hepatitis B and SARS-CoV2 vaccination rates in people who attended Drugs and Addiction Centres
Comparison of hepatitis B and SARS-CoV2 vaccination rates in people who attended Drugs and Addiction Centres Open
Background and aims Persons with substance use disorder are at increased risk for hepatitis B virus (HBV) infection. Although most of them are attached to social health centers, the vaccination rate in this group is low. In this context, w…
View article: Rat hepatitis E virus ( <i>Rocahepevirus ratti</i> ) in people living with HIV
Rat hepatitis E virus ( <i>Rocahepevirus ratti</i> ) in people living with HIV Open
Rat hepatitis E virus (ratHEV; species Rocahepevirus ratti) is considered a newly emerging cause of acute hepatitis of zoonotic origin. ratHEV infection of people living with HIV (PLWH) might portend a worse, as with hepatitis E virus (HEV…
View article: Correlation of hepatitis E and rat hepatitis E viruses urban wastewater monitoring and clinical cases
Correlation of hepatitis E and rat hepatitis E viruses urban wastewater monitoring and clinical cases Open
Our study shows that there is no correlation between clinical cases and wastewater detection of HEV or RHEV.
View article: Effectiveness and safety of bictegravir/emtricitabine/tenofovir alafenamide in HIV late presenters
Effectiveness and safety of bictegravir/emtricitabine/tenofovir alafenamide in HIV late presenters Open
Our results suggest that BIC/FTC/TAF could be a preferred regimen as initial therapy in HIV late presenters because of its high effectiveness and good tolerability.
View article: Correction: Impact of an enhanced screening program on the detection of non-AIDS neoplasias in patients with human immunodeficiency virus infection
Correction: Impact of an enhanced screening program on the detection of non-AIDS neoplasias in patients with human immunodeficiency virus infection Open
Background: The incidence of non-AIDS defining cancer (NADC) is higher in people living with HIV (PLWH) than in the general population, and it is already one of the leading causes of death in the HIV-infected population.It is estimated tha…
View article: Butchering activity is the main risk factor for hepatitis E virus (Paslahepevirus balayani) infection in southwestern Nigeria: a prospective cohort study
Butchering activity is the main risk factor for hepatitis E virus (Paslahepevirus balayani) infection in southwestern Nigeria: a prospective cohort study Open
Introduction Paslahepevirus balayani (Hepatitis E virus; HEV) is an emerging virus that poses as a public health threat. The virus is now reported to be the leading cause of acute viral hepatitis, with a unique impact on African settings. …
View article: Lack of associations of microRNAs with severe NAFLD in people living with HIV: discovery case-control study
Lack of associations of microRNAs with severe NAFLD in people living with HIV: discovery case-control study Open
Background & objective Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in people living with HIV (PLWH) and the expression of some microRNAs could be useful as biomarkers for the diagnosis of NAFLD. The aim of this study w…
View article: Switching to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) plus darunavir/cobicistat in heavily antiretroviral-experienced, virologically suppressed HIV-infected adults receiving complex regimens
Switching to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) plus darunavir/cobicistat in heavily antiretroviral-experienced, virologically suppressed HIV-infected adults receiving complex regimens Open
Objectives To evaluate the efficacy and safety of the two-pill regimen bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) plus darunavir/cobicistat as a switching strategy in heavily treatment-experienced people living with HIV …
View article: Response to glecaprevir/pibrentasvir in HIV/HCV-coinfected patients in clinical practice
Response to glecaprevir/pibrentasvir in HIV/HCV-coinfected patients in clinical practice Open
Objectives HIV infection has been associated with lower rates of sustained viral response (SVR) with direct-acting antivirals (DAAs). There are few data on glecaprevir/pibrentasvir (G/P) in HIV/HCV coinfection outside clinical trials. Meth…