John A. Rogers
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View article: A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block
A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block Open
Conventional strategies for the management of acute pain have significant limitations. Pharmaceutical approaches carry risks for addiction and misuse. Standard implantable devices require secondary surgeries for removal and physical tether…
View article: Continuous wireless sensor monitoring with applied diagnostics: Clinical Sensor Pain Scale and Automated Sensor Pain Scale in the NICU
Continuous wireless sensor monitoring with applied diagnostics: Clinical Sensor Pain Scale and Automated Sensor Pain Scale in the NICU Open
Objectives Inappropriately treated pain can have deleterious outcomes in infants. Current tools rely on intermittent, subjective observation requiring specialised paediatric skills. This study aimed to diagnose infant pain through continuo…
View article: Analytical solutions for light propagation of LED
Analytical solutions for light propagation of LED Open
Analytical solutions of diffusion theory for light propagation in turbid media are essential for optical diagnostics and therapeutic applications, including cerebral oximetry, hemodynamic monitoring, and photostimulation. While existing so…
View article: Remote analysis and management of sweat biomarkers using a wearable microfluidic sticker in adult cystic fibrosis patients
Remote analysis and management of sweat biomarkers using a wearable microfluidic sticker in adult cystic fibrosis patients Open
Sweat parameters such as volume and chloride concentration may offer invaluable clinical insights for people with CF (PwCF). Pilocarpine-induced sweat collection for chloridometry measurement is the gold standard for a CF diagnosis, but th…
View article: 3D printing of dose-flexible crystalline solid dispersion tablets suitable for preclinical and first-in-human studies
3D printing of dose-flexible crystalline solid dispersion tablets suitable for preclinical and first-in-human studies Open
Traditional extemporaneous compounding methods of solid oral dosage forms required in early-stage studies are laborious, and the drug's solid state may affect the biopharmaceutical performance of the medicine. Maintaining the intended drug…
View article: Systematic review of potential developmental and reproductive toxicity of microplastics
Systematic review of potential developmental and reproductive toxicity of microplastics Open
Plastic microparticles, a form of microparticles commonly referred to as microplastics (MP), have been the focus of increasing interest for understanding potential human and ecological impacts, including the development of health-based ben…
View article: Shape Morphing Programmable Systems for Enhanced Control in Low‐Velocity Flow Applications
Shape Morphing Programmable Systems for Enhanced Control in Low‐Velocity Flow Applications Open
Active flow control has gained substantial interest due to the ubiquitous role of fluids in engineering systems and applications and its potential to enhance aero‐, hydro‐, and hemodynamic system performance. This study presents an active …
View article: Minimally Invasive, Bioadaptive Multimodal Sensor Probe with Safe Deployment for Real‐Time Acute Compartment Syndrome Diagnosis
Minimally Invasive, Bioadaptive Multimodal Sensor Probe with Safe Deployment for Real‐Time Acute Compartment Syndrome Diagnosis Open
Acute Compartment Syndrome (ACS) is a serious medical condition that arises from increased pressure within osteofascial compartments, leading to impaired blood flow and potential tissue damage. Early and accurate diagnosis is critical for …
View article: A skin-interfaced wireless wearable device and data analytics approach for sleep-stage and disorder detection
A skin-interfaced wireless wearable device and data analytics approach for sleep-stage and disorder detection Open
Accurate identification of sleep stages and disorders is crucial for maintaining health, preventing chronic conditions, and improving diagnosis and treatment. Direct respiratory measurements, as key biomarkers, are missing in traditional w…
View article: Bioresorbable, wireless dual stimulator for peripheral nerve regeneration
Bioresorbable, wireless dual stimulator for peripheral nerve regeneration Open
Wireless bioresorbable electrical stimulators have broad potential as therapeutic implants. Such devices operate for a clinically relevant duration and then harmlessly dissolve, eliminating the need for surgical removal. A representative a…
View article: Soft, skin-interfaced wireless electrogoniometry systems for continuous monitoring of finger and wrist joints
Soft, skin-interfaced wireless electrogoniometry systems for continuous monitoring of finger and wrist joints Open
Continuous kinematic biofeedback during exercise interventions can lead to improved therapeutic outcomes in hand and wrist rehabilitation. Conventional methods for measuring joint kinematics typically allow only static measurements perform…
View article: Optogenetic activation of the gut-brain axis in freely moving mice using a fully implantable wireless battery-free device
Optogenetic activation of the gut-brain axis in freely moving mice using a fully implantable wireless battery-free device Open
The findings demonstrate that distinct behavioral changes can be induced by wireless activation of the terminal region of the large intestine (distal colon and rectum) in freely moving rodents, using fully implantable battery-free devices.
View article: Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models
Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models Open
Spinal cord stimulation (SCS) for chronic pain management is an invasive therapy involving surgical implantation of electrodes into spinal epidural space. While the clinical value and mechanistic action of the therapy is debated considerab…
View article: Experimental demonstration of transient CHI start-up using a floating biased electrode configuration
Experimental demonstration of transient CHI start-up using a floating biased electrode configuration Open
Transient coaxial helicity injection (CHI) current start-up in a spherical tokamak (ST) has been demonstrated for the first time using a reactor-relevant floating single biased (FSB) electrode configuration on QUEST. Unlike previous applic…
View article: Remote exercise-induced sweat chloride measurements using a wearable microfluidic sticker in cystic fibrosis patients
Remote exercise-induced sweat chloride measurements using a wearable microfluidic sticker in cystic fibrosis patients Open
Sweat parameters such as volume and chloride concentration may offer invaluable clinical insights for people with CF (PwCF). Pilocarpine-induced sweat collection for chloridometry measurement is the gold-standard for sweat chloride, but th…
View article: Wearable microfluidic biosensors with haptic feedback for continuous monitoring of hydration biomarkers in workers
Wearable microfluidic biosensors with haptic feedback for continuous monitoring of hydration biomarkers in workers Open
Real-time monitoring of hydration biomarkers in tandem with biophysical markers can offer valuable physiological insights about heat stress and related thermoregulatory response. These metrics have been challenging to achieve with wearable…
View article: A soft thermal sensor for the continuous assessment of flow in vascular access
A soft thermal sensor for the continuous assessment of flow in vascular access Open
Hemodialysis for chronic kidney disease (CKD) relies on vascular access (VA) devices, such as arteriovenous fistulas (AVF), grafts (AVG), or catheters, to maintain blood flow. Nonetheless, unpredictable progressive vascular stenosis due to…
View article: DDEL-12. LOCAL DELIVERY OF CHEMOTHERAPIES VIA BIORESORBABLE IMPLANT IN MENINGIOMAS
DDEL-12. LOCAL DELIVERY OF CHEMOTHERAPIES VIA BIORESORBABLE IMPLANT IN MENINGIOMAS Open
Many meningiomas recur despite repeated surgical resections and radiation, and patients must undergo progressively morbid surgical procedures due to recurrent or progressive disease. However, unlike most gliomas, meningiomas do not diffuse…
View article: Minimally invasive flexible, wireless multimodal probe to detect compartment syndrome
Minimally invasive flexible, wireless multimodal probe to detect compartment syndrome Open
Acute Compartment Syndrome (ACS) is a serious medical condition that arises from increased pressure within muscle compartments, leading to impaired blood flow and potential tissue damage. Early and accurate diagnosis is critical for preven…