Sunil A. Sheth
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View article: Sex Differences in the Protective Effect of Brain Volume: Age Attenuates Protection in Females
Sex Differences in the Protective Effect of Brain Volume: Age Attenuates Protection in Females Open
Background Sex differences in outcomes after acute ischemic stroke (AIS) are well recognized, but mechanisms remain unclear. This study evaluates whether parenchymal brain volume (PBV), age, and final infarct volume (DWI-FIV) explain sex-s…
View article: Abstract 407: Key Predictors Of 90‐Day Functional Outcome For Patients With Large Infarct Core Undergoing Endovascular Therapy In Real‐World Practice
Abstract 407: Key Predictors Of 90‐Day Functional Outcome For Patients With Large Infarct Core Undergoing Endovascular Therapy In Real‐World Practice Open
Background Recent randomized trials have shown a benefit for patients with large infarct core undergoing endovascular therapy (EVT), however the key factors to predict long‐term functional outcome remain unclear. Here in this real‐world re…
View article: Abstract 519: A Scoring System for Pre‐Thrombectomy Diagnosis of Intracranial Atherosclerotic Disease in Posterior Circulation (Score‐ICAD‐PC)
Abstract 519: A Scoring System for Pre‐Thrombectomy Diagnosis of Intracranial Atherosclerotic Disease in Posterior Circulation (Score‐ICAD‐PC) Open
INTRODUCTION Early identification of intracranial atherosclerotic disease(ICAD) may influence management strategies in patients undergoing mechanical thrombectomy(MT). We have previously developed a scoring system for pre‐thrombectomy diag…
View article: Thrombi from stroke due to cardioembolic etiology have higher CD11b-positive cells compared to large artery atherosclerosis
Thrombi from stroke due to cardioembolic etiology have higher CD11b-positive cells compared to large artery atherosclerosis Open
Identifying the underlying etiology of ischemic stroke is crucial for implementing effective stroke prevention measures. In the era of thrombectomy, ischemic stroke thrombus composition has gained considerable interest in the recent years.…
View article: Anatomical Correlation between Ulnar Neuropathy and Triceps in Electrodiagnostic Studies
Anatomical Correlation between Ulnar Neuropathy and Triceps in Electrodiagnostic Studies Open
Introduction: Nerve conduction studies (NCV) and electromyography (EMG) are key diagnostic tools for identifying mononeuropathy and radiculopathy. Triceps denervation has traditionally been attributed to C7 radiculopathy or radial neuropat…
View article: A novel automated CT biomarker to predict outcomes in acute ischemic stroke: net water uptake
A novel automated CT biomarker to predict outcomes in acute ischemic stroke: net water uptake Open
Background Recent trials of large core thrombectomy have shown that our traditional understanding of infarct characteristics and reperfusion benefit may be incomplete for patients with acute ischemic stroke (AIS). The Alberta Stroke Progra…
View article: A Multi-Modal Pelvic MRI Dataset for Deep Learning-Based Pelvic Organ Segmentation in Endometriosis
A Multi-Modal Pelvic MRI Dataset for Deep Learning-Based Pelvic Organ Segmentation in Endometriosis Open
Endometriosis affects approximately 190 million females of reproductive age worldwide. Magnetic Resonance Imaging (MRI) has been recommended as the primary non-invasive diagnostic method for endometriosis. This study presents new female pe…
View article: PRALINE: study protocol for a phase IIb inpatient stroke rehabilitation randomized controlled trial investigating longitudinal outcomes after progressive abduction loading therapy
PRALINE: study protocol for a phase IIb inpatient stroke rehabilitation randomized controlled trial investigating longitudinal outcomes after progressive abduction loading therapy Open
Clinicaltrials.gov, NCT04118998. Registered on 8 October 2019.
View article: Baseline predictors of poor clinical outcome despite recanalization of distal middle cerebral artery occlusions
Baseline predictors of poor clinical outcome despite recanalization of distal middle cerebral artery occlusions Open
Objective Mechanical thrombectomy (MT) is well-established for the treatment of acute ischemic stroke (AIS) from large vessel occlusion (LVO), with growing data supporting the expansion to distal and medium vessel occlusions (DMVO). Despit…
View article: Endovascular Thrombectomy Technique Optimization: A SVIN Registry Analysis
Endovascular Thrombectomy Technique Optimization: A SVIN Registry Analysis Open
Background Achieving excellent recanalization (Modified Thrombolysis in Cerebral Infarction 2c/3) in fewer attempts improves clinical outcomes. Previous studies suggest that switching techniques after a failed first pass may enhance reperf…
View article: Examining the Impact of Area Deprivation on Endovascular Stroke Therapy Access
Examining the Impact of Area Deprivation on Endovascular Stroke Therapy Access Open
Background Equitable access to health care is heavily affected by socioeconomic factors. However, the effects of such disparities in accessing life‐saving treatments remain incompletely characterized. Here we explore the impact of disparit…
View article: A multicenter, propensity score-matched analysis of functional outcomes and recanalization success with or without Trevo for Medium and distal vessel occlusion
A multicenter, propensity score-matched analysis of functional outcomes and recanalization success with or without Trevo for Medium and distal vessel occlusion Open
Background Endovascular therapy (EVT) for stroke due to distal or medium vessel occlusion (DMVO) is safe. Due to the distinct anatomical characteristics of DMVOs, further evaluation of EVT is crucial to determine which devices may yield be…
View article: 1293 Prevalence of Stroke and TIA in Insomniacs and Sleep Evaluation Differences: A Tertiary Center Perspective
1293 Prevalence of Stroke and TIA in Insomniacs and Sleep Evaluation Differences: A Tertiary Center Perspective Open
Introduction Sleep is essential for neuronal, metabolic and vascular health. Insomnia increases stroke risk through development of hypertension, diabetes mellitus and hyperlipidemia. Stroke causes insomnia by altering sleep architecture. I…
View article: Patients Residing in Rural Areas Transferred for Mechanical Thrombectomy Undergo Decreased Catheter‐Based Treatment
Patients Residing in Rural Areas Transferred for Mechanical Thrombectomy Undergo Decreased Catheter‐Based Treatment Open
Background Nearly one fifth of the US population resides in rural areas. Although endovascular therapy can substantially improve clinical outcomes in patients treated with large vessel occlusion acute ischemic stroke, the penetration and o…
View article: Efficacy and safety of mechanical thrombectomy in distal medium middle cerebral artery occlusion ischemic stroke patients on low-dose aspirin
Efficacy and safety of mechanical thrombectomy in distal medium middle cerebral artery occlusion ischemic stroke patients on low-dose aspirin Open
Background: Acute ischemic stroke (AIS) from distal medium vessel occlusion (DMVO) presents unique treatment challenges. Mechanical thrombectomy (MT) is emerging as a viable option for these patients, yet the role of pre-stroke aspirin tre…
View article: Clinical outcomes of patients with unsuccessful mechanical thrombectomy versus best medical management of medium vessel occlusion stroke in the middle cerebral artery territory
Clinical outcomes of patients with unsuccessful mechanical thrombectomy versus best medical management of medium vessel occlusion stroke in the middle cerebral artery territory Open
Background Current randomized controlled trials are investigating the efficacy and safety of mechanical thrombectomy (MT) in patients with medium vessel occlusion (MeVO) stroke. Whether best medical management (MM) is more efficient than u…
View article: Middle Meningeal Artery Embolization Does Not Confer Protection against Symptomatic Recurrence in Patients with Early Antithrombotic Therapy Following Surgery for Chronic Subdural Hematomas
Middle Meningeal Artery Embolization Does Not Confer Protection against Symptomatic Recurrence in Patients with Early Antithrombotic Therapy Following Surgery for Chronic Subdural Hematomas Open
In this single-center cohort study, we found no clear benefit in reduced rates of reoperation or recurrence for adjunctive MMAE in patients with cSDH treated with surgical evaluation. Despite this, encouraging trends were observed in the M…
View article: Association of Age, Sex and Education With Access to the Intravenous Thrombolysis for Acute Ischemic Stroke
Association of Age, Sex and Education With Access to the Intravenous Thrombolysis for Acute Ischemic Stroke Open
Most patients with AIS present outside IVT eligibility in South Korea, and only 60% of eligible patients were ultimately treated. We identified increased age, female sex and lower education as key features on which to focus interventions f…
View article: Endovascular Treatment of Patients With Acute Ischemic Stroke With Tandem Lesions Presenting With Low Alberta Stroke Program Early Computed Tomography Score
Endovascular Treatment of Patients With Acute Ischemic Stroke With Tandem Lesions Presenting With Low Alberta Stroke Program Early Computed Tomography Score Open
Background Recent trials confirmed the efficacy and safety of endovascular thrombectomy in patients with low Alberta Stroke Program Early Computed Tomography Score (ASPECTS); however, evidence in tandem lesions is limited. This study evalu…
View article: Abstract 332: Multi‐Center Comparison of Safety and Efficacy of Intravenous Thrombolytics in Patients Undergoing Endovascular Therapy: Regression Discontinuity Analysis
Abstract 332: Multi‐Center Comparison of Safety and Efficacy of Intravenous Thrombolytics in Patients Undergoing Endovascular Therapy: Regression Discontinuity Analysis Open
Introduction Many clinical practices have switched from alteplase (tPA) to tenecteplase (TNK) given recent clinical trial results. The safety and efficacy of TNK in endovascular treated cohorts, compared to tPA and no thrombolytic remain i…