Aletta E. Schutte
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Physical activity and inflammation among young adults in the African-PREDICT study: Comparison of three self-report and objective physical activity measures Open
We examined cross-sectional associations between physical activity and inflammatory markers among 1202 ethnically diverse South African young adults. Global Physical Activity Questionnaire (GPAQ), Godin Leisure-Time Exercise Questionnaire …
View article: Bridging the gap between hypertension guidelines and real-life practice: strategies and technological tools for improving long-term population blood pressure control
Bridging the gap between hypertension guidelines and real-life practice: strategies and technological tools for improving long-term population blood pressure control Open
Hypertension is the leading cardiovascular risk factor. However, despite the availability of safe and effective antihypertensive drugs, blood pressure (BP) control rates remain low worldwide. In this context, the recent European hypertensi…
How and why do Australians obtain blood pressure devices for use at home? A mixed-methods study revealing health literacy responsive ways to support this self-management behaviour Open
Background Adequate health literacy is integral to support self-management behaviours, including home blood pressure (BP) monitoring, which is recommended for hypertension management. Using a validated device that has been tested for accur…
Delivery models to improve adherence to medicines for chronic diseases in primary care Open
Global efforts to improve medication adherence have increasingly recognised that suboptimal control of chronic diseases is shaped not only by patient behaviour but also by the design and performance of health-care delivery systems. Althoug…
Acute blood pressure responses to plank and wall sit isometric exercise in adults Open
Objectives: Isometric exercise is an accessible, time efficient intervention for reducing blood pressure (BP). However, guideline recommendations for its use remain sparse due to safety concerns. This study aimed to determine the proportio…
View article: Potassium-enriched salt for patients with hypertension: a Hypertension Australia and National Hypertension Taskforce of Australia Position Statement
Potassium-enriched salt for patients with hypertension: a Hypertension Australia and National Hypertension Taskforce of Australia Position Statement Open
Introduction: High blood pressure remains the leading risk factor for cardiovascular and all-cause deaths in Australia. Higher sodium and lower potassium intake are well established risk factors for elevated blood pressure and increased ca…
Therapeutic Adherence in Cardiovascular Diseases: Insights from the Patient and Physician—A Narrative Review Open
Therapeutic adherence is defined as the extent to which patients' medication-taking behaviour corresponds with agreed recommendations from a clinician. Adherence to cardiovascular therapies significantly improves outcomes and improves pati…
View article: Long-Term Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination for the Treatment of Hypertension
Long-Term Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination for the Treatment of Hypertension Open
Background: A novel low-dose triple single-pill combination of antihypertensive drugs (GMRx2) has demonstrated superior blood pressure (BP)-lowering efficacy compared to placebo and dual combinations in short-term randomized double-blind t…
View article: Heart Stress and Blood Pressure Management in Older Adults: Post Hoc Analysis of the ASPREE Trial
Heart Stress and Blood Pressure Management in Older Adults: Post Hoc Analysis of the ASPREE Trial Open
BACKGROUND: Blood pressure (BP) management in older adults is complex because of age-related physiological changes and uncertainty around ideal systolic BP (SBP) targets. Heart stress (HS), defined by age-adjusted elevation in NT-proBNP (N…
View article: Magnesium Supplementation and Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Magnesium Supplementation and Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
BACKGROUND: There are inconsistent reports regarding the effect of magnesium intake on blood pressure (BP) across hypertensive and normotensive populations. METHODS: We performed a meta-analysis and dose-response analysis to explore the re…
View article: Bridging Hypertension Care Shortfalls Between Provider Capacity and Patient Needs: A Pooled Analysis of Data From 199 Countries and Territories
Bridging Hypertension Care Shortfalls Between Provider Capacity and Patient Needs: A Pooled Analysis of Data From 199 Countries and Territories Open
BACKGROUND: This study estimates the overall gaps between health system capacity of physician and nonphysician providers (nurses, pharmacists, and community health workers) and patients’ needs for hypertension management across country inc…
Community Practices and Perceptions Regarding Blood Pressure Measurement Techniques Open
Background Despite various blood pressure (BP) measurement methods being available, many people report never or infrequently having their BP measured. There is a gap between clinical guidelines and the implementation of BP monitoring. To b…
View article: Poor Accuracy of Blood Pressure Measurement Images Online: Implications for Public Health Education
Poor Accuracy of Blood Pressure Measurement Images Online: Implications for Public Health Education Open
BACKGROUND: Blood pressure (BP) is a common clinical measurement, now increasingly done at home. Media websites often display images of BP measurement to represent clinical medicine, but many images deviate from guidelines, potentially cre…
View article: Does Ideal Blood Pressure Vary by Cognitive Domain? A UK Biobank Study
Does Ideal Blood Pressure Vary by Cognitive Domain? A UK Biobank Study Open
High blood pressure (BP) is a risk factor for cognitive decline. Increasingly, studies have found the relationship to be nonlinear, with low BP also indicating higher risk. This UK Biobank study examines the nonlinear relationships between…
View article: Evaluation of race-free eGFR equations in individuals of different ethnicity
Evaluation of race-free eGFR equations in individuals of different ethnicity Open
The NHANES mortality outcomes support the use of eGFRcys and eGFRcr-cys. However, large intraindividual variability between eGFR estimates may lead to KDIGO eGFR stage misclassification and calls for caution in the opportunistic or systema…
View article: Interventions for the management of concomitant COPD and hypertension: A systematic review
Interventions for the management of concomitant COPD and hypertension: A systematic review Open
Background: Chronic obstructive pulmonary disease (COPD) and hypertension are prevalent public health burdens, with hypertension often co-existing in up to 65% of COPD patients and complicating patient management. While numerous clinical g…
Low-Dose Combinations With 3 or 4 Blood Pressure–Lowering Medications for the Treatment of Hypertension Open
Single pill LDCs are effective and safe as an initial treatment option for hypertension. The degree of BP reduction depends strongly on pretreatment BP level.
View article: Automated office blood pressure measurement: a Hypertension Australia and National Hypertension Taskforce of Australia position statement
Automated office blood pressure measurement: a Hypertension Australia and National Hypertension Taskforce of Australia position statement Open
Hypertension is the most common problem managed in Australian general practice, yet most adults with hypertension do not have their blood pressure (BP) treated to target. Hypertension diagnosis and management rely upon accurate BP measurem…
Treating hypertension with single pill combinations: a simple strategy to save costs for the patients and payers Open
Objectives: Our aim was to compare direct costs for single pill combinations (SPCs) and free-drug combinations for hypertension treatment. Methods: We focused on Australia as a case study and reviewed total costs, and for the patient and g…
View article: Nocturnal blood pressure: pathophysiology, measurement and clinical implications. Position paper of the European Society of Hypertension
Nocturnal blood pressure: pathophysiology, measurement and clinical implications. Position paper of the European Society of Hypertension Open
Interest in the pathophysiology, measurement, and clinical implications of nocturnal blood pressure (BP) has significantly increased due to its strong association with cardiovascular risk, and its importance was recognized by the 2023 Euro…
View article: Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 Open
Background: HEARTS in the Americas is the regional adaptation of the WHO Global HEARTS Initiative, aimed at helping countries enhance hypertension and cardiovascular disease (CVD) risk management in primary care settings. Its core implemen…
High Burden and Trend in Nonadherence to Blood Pressure‐Lowering Medications: Meta‐Analysis of Data From Over 34 000 Adults With Hypertension in Sub‐Saharan Africa Open
Background Nonadherence to blood pressure (BP)‐lowering medication is a strong predictor of poor BP control. Sub‐Saharan Africa has extremely low BP control rates (~10%), but it is unclear what the burden of medication nonadherence among A…
View article: EVALUATION OF RACE-FREE EGFR EQUATIONS IN INDIVIDUALS OF DIFFERENT ETHNICITY
EVALUATION OF RACE-FREE EGFR EQUATIONS IN INDIVIDUALS OF DIFFERENT ETHNICITY Open
Objective: This study aimed to evaluate the impact of CKD age-defined definition on all-cause mortality and cardiovascular (CV) outcomes in a rural population over 136 months long-term follow-up (2005-2022). Design and method: A total of 1…
How and why do Australians obtain blood pressure devices for use at home? A mixed-methods study Open
Background Only 10-20% of blood pressure (BP) devices available are validated. Little is known about how and why patients choose BP devices for home BP measurement (HBPM), which was the aim of this study. Methods Mixed-methods study (onlin…