Şengül Alpay Karaoğlu
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View article: Evaluation of synthesized methoxy chalcones for therapeutic potential through in vitro and in silico methods
Evaluation of synthesized methoxy chalcones for therapeutic potential through in vitro and in silico methods Open
Chalcones are the precursors of flavonoids and have a wide range of biological activities. A series of methoxy chalcones (1-12) were synthesized using the Claisen-Schmidt method and identified by NMR analyses. Enzyme inhibition, antimicrob…
View article: Determination of tannin activity and Paenibacillus alvei (Cheshire & Cheyne) Ash et al. (Bacillii: Paenibacillaceae) on the biocontrol of tannin-tolerant Agelastica alni L., 1758 (Coleoptera: Chrysomelidae) larvae
Determination of tannin activity and Paenibacillus alvei (Cheshire & Cheyne) Ash et al. (Bacillii: Paenibacillaceae) on the biocontrol of tannin-tolerant Agelastica alni L., 1758 (Coleoptera: Chrysomelidae) larvae Open
Tannins are among the most abundant secondary metabolites synthesized by plants. Agelastica alni L., 1758 (Coleoptera: Chrysomelidae) is a critical forest pest. This study investigated the effect of Paenibacillus alvei (Cheshire & Chey…
View article: Production Starch Using the Yeast ( <i>Cryptococcus neoformans</i> HTM1 Strain) Isolated From Tea ( <i>Camellia sinensis</i> )
Production Starch Using the Yeast ( <i>Cryptococcus neoformans</i> HTM1 Strain) Isolated From Tea ( <i>Camellia sinensis</i> ) Open
Starch is a staple food in human and animal nutrition as well as a widely used raw material in industry. This study determined the capacity of producing starch of a new yeast culture, which was defined as Cryptococcus neoformans HTM1 strai…
View article: Synthesis of Novel Thiazole/Thiadiazole Conjugates of Fluoroquinolones as Potent Antibacterial and Antimycobacterial Agents
Synthesis of Novel Thiazole/Thiadiazole Conjugates of Fluoroquinolones as Potent Antibacterial and Antimycobacterial Agents Open
Twenty azole‐fluoroquinolone hybrids were designed and synthesized by conjugating thiazole and thiadiazole structures to ciprofloxacin and norfloxacin via a 2‐oxoethyl bridge. The structures and purities of the synthesized compounds were p…
View article: Comparative Chemical Composition and Antimicrobial Activities of The Essential Oils and Solvent Extracts of The Flower, Leaf, And Stem of Epilobium angustifolium Growing in Türkiye
Comparative Chemical Composition and Antimicrobial Activities of The Essential Oils and Solvent Extracts of The Flower, Leaf, And Stem of Epilobium angustifolium Growing in Türkiye Open
Volatile organic compounds (VOCs) of essential oils (EOs) and solid phase microextract (SPME) obtained from the flower, leaf, and stem of Epilobium angustifolium L. were analyzed by GC-FID/MS. The EOs and SPMEs consist mainly of monoterpen…
View article: Production of Prophylactic Nanoformulation for Dental Caries and Investigation of Its Effectiveness by In Vitro and In Silico Methods
Production of Prophylactic Nanoformulation for Dental Caries and Investigation of Its Effectiveness by In Vitro and In Silico Methods Open
Background/Objectives: This study aimed to develop cinnamon bark essential oil (CEO), orange peel essential oil(OEO) and the combination of these two essential oils (OEO-CEO) loaded PLGA nanoparticles to prevent dental caries and to invest…
View article: Determination of The Prevalence of Honey Bee Diseases and Parasites in Samples from Sivas Province
Determination of The Prevalence of Honey Bee Diseases and Parasites in Samples from Sivas Province Open
Honey bees, Apis mellifera L. (Hymenoptera: Apidae), are the most important pollinators of agricultural products and plants in the natural environment. Honeybees are an important ecosystem component due to their role in nature and agricult…
View article: Antioxidative and Antimicrobial Activity of 2-Amino Substituted Halochalcone N-Glycoside Derivative Compounds
Antioxidative and Antimicrobial Activity of 2-Amino Substituted Halochalcone N-Glycoside Derivative Compounds Open
Introduction: The aim of this study was to specify the antioxidant and antimicrobial activity synthesized 2-amino substituted halochalcone N-glycoside derivative compounds. Methods: The antioxidant capacity of synthesized compounds (1-4) w…
View article: Parentucellia viscosa (growing in Türkiye): Essential oil, phenolic composition, antimicrobial and lipase inhibition
Parentucellia viscosa (growing in Türkiye): Essential oil, phenolic composition, antimicrobial and lipase inhibition Open
The essential oil (EO) and phenolic constituents of Parentucellia viscosa L. were analyzed by GC-FID-MS and HPLC, respectively. A total of 20 volatile compounds were identified accounting for 99.97% in hydrodistillation. Monoterpenes (50.5…
View article: ISOLATION AND CHARACTERIZATION OF WATER SOLUBLE FRACTION OF PROPOLIS AND ITS ANTIBACTERIAL POTENTIAL ON BACTERIA CAUSING CONJUNCTIVITIS
ISOLATION AND CHARACTERIZATION OF WATER SOLUBLE FRACTION OF PROPOLIS AND ITS ANTIBACTERIAL POTENTIAL ON BACTERIA CAUSING CONJUNCTIVITIS Open
Propolis is a bee product with a variety of biological activities. Although chemical composition of propolis differs by the location but all propolis types possesses antimicrobial activity. The usage of propolis for apitherapeutic purposes…
View article: ANALYSIS OF VOLATILE COMPOUNDS OF ALCEA CALVERTII BOISS. AND ITS ANTIMICROBIAL, ANTICHOLINESTERASE, AND ANTITYROSINASE POTENCY
ANALYSIS OF VOLATILE COMPOUNDS OF ALCEA CALVERTII BOISS. AND ITS ANTIMICROBIAL, ANTICHOLINESTERASE, AND ANTITYROSINASE POTENCY Open
The research aimed to analyze the volatile compounds by using SPME-GC-MS and to detect anticholinesterase, antityrosinase, and antimicrobial potential of metanol extract of Alceacalvertii Boiss., an endemic species for Türkiye. The inhibit…
View article: Characterization of chitin and description of its antimicrobial properties obtained from Cydalima perspectalis adults
Characterization of chitin and description of its antimicrobial properties obtained from Cydalima perspectalis adults Open
Chitin is the most abundant biopolymer group after cellulose and forms the exoskeleton of arthropods, the largest animal group. The morphology of chitin differs between and within species. In this study, we determined the physicochemical a…
View article: Antioxidative, Antimicrobial Activity and HPLC Analysis of Ornithogalum pyrenaicum
Antioxidative, Antimicrobial Activity and HPLC Analysis of Ornithogalum pyrenaicum Open
Introduction: The aim of this study was to specify the antioxidant, antimicrobial activity and phenolic contents of Ornithogalum pyrenaicum. Methods: The antioxidant capacity of O. pyrenaicum was determined by 2,2-diphenylpicrylhydrazyl (D…
View article: Determination of plant growth promoting properties and bioremediation potentials of Bacillus mycoides Flügge and B. thuringiensis Berliner
Determination of plant growth promoting properties and bioremediation potentials of Bacillus mycoides Flügge and B. thuringiensis Berliner Open
Industrial activities destroying natural resources for decades have been one of the most significant factors in environmental destruction. As a result of industrialization, environmental pollutants became one of the biggest threats for the…
View article: Determination of Bioremediation Potentials and Plant Growth-Promoting Properties of Bacillus Species Isolated from The Rhizosphere of Dactylorhiza urvilleana
Determination of Bioremediation Potentials and Plant Growth-Promoting Properties of Bacillus Species Isolated from The Rhizosphere of Dactylorhiza urvilleana Open
Industrial activities have been one of the biggest factors of environmental destruction by affecting natural resources for decades. Heavy metals, which are one of the greatest dangers especially for the biosphere, can be found in industria…
View article: Investigation of wound healing potentials of Lysimachia verticillaris and Lysimachia vulgaris: In vivo and in vitro studies
Investigation of wound healing potentials of Lysimachia verticillaris and Lysimachia vulgaris: In vivo and in vitro studies Open
In this study, the wound healing potential of L. verticillaris and L. vulgaris were investigated in vivo with the "Circular Excision Wound Model". Changes in wound healing have been observed with biological activity and histopathological s…
View article: Inhibitive and prophylactic efficacy of lactic acid bacteria from <i>Apis mellifera</i> (Hymenoptera: Apidae) in combating <i>Paenibacillus</i> infections
Inhibitive and prophylactic efficacy of lactic acid bacteria from <i>Apis mellifera</i> (Hymenoptera: Apidae) in combating <i>Paenibacillus</i> infections Open
Given the increasing interest in alternative methods of prevention and biological control of bacterial diseases in honey bees, the development of new approaches based on probiotic bacteria for honey bee growth, immune function and defense …
View article: Nosemosis in Türkiye: Increasing prevalence and distribution on two decades, and phylogenetic network analysis based on SSU rRNA gene
Nosemosis in Türkiye: Increasing prevalence and distribution on two decades, and phylogenetic network analysis based on SSU rRNA gene Open
Nosemosis, one of the most important honeybee diseases, causes colony losses and low productivity worldwide. A national study were carried out to presence of nosemosis throughout Türkiye, determine the prevalence of Nosema cereane and Nose…
View article: The Effect of Disinfection Methods on C. Albicans in Three Types of Denture Base Materials
The Effect of Disinfection Methods on C. Albicans in Three Types of Denture Base Materials Open
This study aimed to evaluate the efficacy of disinfectant solutions on Candida albicans (C. albicans) for different types of denture materials. A total of 144 specimens (10x10x2 mm) were obtained from three different materials: autopolymer…
View article: PCR-Based Detection of the Honeybee Tracheal Mite (Acarapis woodi) in Türkiye
PCR-Based Detection of the Honeybee Tracheal Mite (Acarapis woodi) in Türkiye Open
Acarapis woodi (Rennie, 1921) (Acari: Tarsonemidae) is one of the mites that settles in the respiratory system of honeybees ( Apis mellifera L. (Hymenoptera, Apidae)) and distributed throughout the world. It causes significant economic los…
View article: Synthesis of Some New 4-methylpiperazin-1-yl-methyl-4H-1,2,4-triazole-3- thiol Derivatives of Expected Anticancer and Antimicrobial Activity
Synthesis of Some New 4-methylpiperazin-1-yl-methyl-4H-1,2,4-triazole-3- thiol Derivatives of Expected Anticancer and Antimicrobial Activity Open
Different series of annulated methylpiperazine derivatives were designed, synthesized traditional methods, ana structurally characterized. 1,2,4-Triazole-fluoroquinolone and 1,2,4-triazole–conazole hybrids are designed, synthesized, and in…
View article: Do Different Substrates Affect Antioxidant Properties and Antimicrobial Activity of Pleurotus ostreatus?
Do Different Substrates Affect Antioxidant Properties and Antimicrobial Activity of Pleurotus ostreatus? Open
The aim of this study is to determine the effect of growing media on antioxidant properties and antimicrobial activities of Pleurotus ostreatus(Jacq. ex Fr.) P. Kumm. In the study, growing substrates were prepared with five tree sawdust (8…
View article: Identification of Bacteria Obtained From Dactylorhiza urvilleana Rizoid Region, Metal Tolerances, Bioremidant Characteristics and Effects on Zea mays Germination in Copper Presence
Identification of Bacteria Obtained From Dactylorhiza urvilleana Rizoid Region, Metal Tolerances, Bioremidant Characteristics and Effects on Zea mays Germination in Copper Presence Open
Rapidly increasing industrialization and technological developments cause hazardous wastes to spread to the environment at a high rate. When heavy metal accumulation in water and soil reaches undesirable levels, it causes universal health …