Antonia Shand
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View article: Identification of potential NAD-related biomarkers of recurrent miscarriage risk
Identification of potential NAD-related biomarkers of recurrent miscarriage risk Open
STUDY QUESTION Do women with a history of recurrent miscarriage have altered nicotinamide adenine dinucleotide (NAD)-related metabolites that can be detected in blood, plasma, or urine samples? SUMMARY ANSWER Women with a history of recurr…
View article: Current Breastfeeding Attitudes, Knowledge and Confidence of Obstetricians and Gynaecologists in Australia and New Zealand
Current Breastfeeding Attitudes, Knowledge and Confidence of Obstetricians and Gynaecologists in Australia and New Zealand Open
Background There are limited data on what obstetricians and gynaecologists (O&G) know and think about supporting breastfeeding women. Aims To investigate breastfeeding attitudes, knowledge and confidence of Australian and New Zealand O&G s…
View article: Maternal Circulatory <scp>NAD</scp> Precursor Levels and the Yolk Sac Determine <scp>NAD</scp> Deficiency‐Driven Congenital Malformation Risk
Maternal Circulatory <span>NAD</span> Precursor Levels and the Yolk Sac Determine <span>NAD</span> Deficiency‐Driven Congenital Malformation Risk Open
Nicotinamide adenine dinucleotide (NAD) is an essential cofactor in hundreds of cellular processes. Genetic disruption of NAD de novo synthesis causes congenital NAD deficiency disorder (CNDD), characterized by multiple congenital malforma…
View article: Analgesic opioids in pregnancy and placental malperfusion-related disorders: a population-based cohort study
Analgesic opioids in pregnancy and placental malperfusion-related disorders: a population-based cohort study Open
Background Analgesic opioid use in pregnancy could increase the risk of disorders related to placental malperfusion, but this relationship is incompletely characterized. We aimed to study the causal association between analgesic opioids in…
View article: Educating antenatal patients about cytomegalovirus infection: An e-learning package improves general practitioners’ knowledge and intention to implement clinical guidelines
Educating antenatal patients about cytomegalovirus infection: An e-learning package improves general practitioners’ knowledge and intention to implement clinical guidelines Open
Targeted e-learning can improve GP knowledge and confidence, and can support the implementation of the national congenital CMV risk-reduction guidelines.
View article: The first live term birth following uterus transplantation in Australia
The first live term birth following uterus transplantation in Australia Open
Objective To report the first live birth following uterus transplantation in Australia. Study design Case report. Setting, participant The first participant in the uterus transplantation research study program at the Royal Hospital for Wom…
View article: A 2‐Min Cytomegalovirus ( <scp>CMV</scp> ) Awareness Video Improves Pregnant Women's Knowledge and Planned Adherence to Hygiene Precautions
A 2‐Min Cytomegalovirus ( <span>CMV</span> ) Awareness Video Improves Pregnant Women's Knowledge and Planned Adherence to Hygiene Precautions Open
Introduction Congenital cytomegalovirus (cCMV) is a leading infectious cause of life‐long neurodevelopmental disabilities, but public awareness of CMV is low. This study evaluated a short educational video on cCMV for its acceptability and…
View article: Long-term health, neurodevelopmental, and educational outcomes of children born to mothers with hyperemesis gravidarum: a population-based sibling-design record linkage cohort study
Long-term health, neurodevelopmental, and educational outcomes of children born to mothers with hyperemesis gravidarum: a population-based sibling-design record linkage cohort study Open
We did not find an association between HG exposure and long-term educational, neurodevelopmental, and health outcomes for children when accounting for shared family influences using a sibling-comparison design. The lack of evidence of a di…
View article: Haematological malignancies during pregnancy: a systematic review of necessary services in the Australian context
Haematological malignancies during pregnancy: a systematic review of necessary services in the Australian context Open
Background Haematological malignancies diagnosed during pregnancy are rare, with increasing incidence, presenting unique therapeutic, social and ethical challenges for treating teams, patients and their family. There are no national guidel…
View article: Beating the Odds: A Successful Pregnancy in a Patient With ALK‐Rearranged Lung Cancer on Alectinib
Beating the Odds: A Successful Pregnancy in a Patient With ALK‐Rearranged Lung Cancer on Alectinib Open
The management of oncogene‐driven non–small cell lung cancer (NSCLC) during pregnancy presents unique challenges due to limited safety data on targeted therapies. Anaplastic lymphoma kinase (ALK)‐rearranged NSCLC is a rare but increasingly…
View article: Risk factors and recurrence of hyperemesis gravidarum: A population‐based record linkage cohort study
Risk factors and recurrence of hyperemesis gravidarum: A population‐based record linkage cohort study Open
Introduction There are limited contemporary population‐based studies on the risk factors for hyperemesis gravidarum (HG), a severe type of nausea and vomiting in pregnancy. This study aimed to determine the prevalence and trend of HG over …
View article: Protocol for the Australian Type 1 Diabetes National Screening Pilot: Assessing the feasibility and acceptability of three general population screening models in children
Protocol for the Australian Type 1 Diabetes National Screening Pilot: Assessing the feasibility and acceptability of three general population screening models in children Open
Aim One third of Australian children diagnosed with type 1 diabetes present with life‐threatening diabetic ketoacidosis (DKA) at diagnosis. Screening for early‐stage, presymptomatic type 1 diabetes, with ongoing follow‐up, can substantiall…
View article: Opioid analgesic exposure during the first trimester of pregnancy and the risk of major congenital malformations in infants: a systematic review and meta‐analysis <sup>†</sup>
Opioid analgesic exposure during the first trimester of pregnancy and the risk of major congenital malformations in infants: a systematic review and meta‐analysis <sup>†</sup> Open
Summary Background Prescribed opioid analgesics are frequently used to manage pain in pregnancy. However, the available literature regarding the teratogenic potential of opioid use during pregnancy has not been systematically summarised. T…
View article: Association between cumulative maternal exposures related to inflammation and child attention‐deficit/hyperactivity disorder: A cohort study
Association between cumulative maternal exposures related to inflammation and child attention‐deficit/hyperactivity disorder: A cohort study Open
Background Preclinical studies suggest synergistic effects of maternal inflammatory exposures on offspring neurodevelopment, but human studies have been limited. Objectives To examine the cumulative association and potential interactions b…
View article: EP21.05: Clinical and molecular findings in a rare case of orofaciodigital syndrome type 14
EP21.05: Clinical and molecular findings in a rare case of orofaciodigital syndrome type 14 Open
Orofaciodigital syndrome (OFD) belongs to a group of disorders affecting primary cilia genes important in early development. OFD is associated with neuronal, orofacial and digital anomalies. Recently, bi-allelic variants in the C2CD3 gene …
View article: Intrahepatic cholestasis of pregnancy – Diagnosis and management: A consensus statement of the Society of Obstetric Medicine of Australia and New Zealand (<scp>SOMANZ</scp>): Executive summary
Intrahepatic cholestasis of pregnancy – Diagnosis and management: A consensus statement of the Society of Obstetric Medicine of Australia and New Zealand (<span>SOMANZ</span>): Executive summary Open
KEY POINTS Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy liver disease, characterised by pruritus and increased total serum bile acids (TSBA), Australian incidence 0.6–0.7%. ICP is diagnosed by non‐fasting TSBA ≥ 19 μmol/L in …
View article: Acne
Acne Open
Aims: Oral retinoids are teratogenic in pregnancy, and contraception is recommended to prevent pregnancy.This study assessed the demographic characteristics and trends in use of prescription retinoids and contraception among reproductive-a…
View article: Association of maternal autoimmune disease and early childhood infections with offspring autism spectrum disorder: A population‐based cohort study
Association of maternal autoimmune disease and early childhood infections with offspring autism spectrum disorder: A population‐based cohort study Open
The aim of this study was to examine potential synergistic effects between maternal autoimmune disease and early childhood infections and their association with autism spectrum disorder (ASD) in offspring. Both exposures have been associat…
View article: The National <scp>COVID</scp> ‐19 Clinical Evidence Taskforce: pregnancy and perinatal guidelines
The National <span>COVID</span> ‐19 Clinical Evidence Taskforce: pregnancy and perinatal guidelines Open
The National COVID-19 Clinical Evidence Taskforce has been a critical component of the infrastructure to support Australian maternity care providers during the COVID-19 pandemic. The Taskforce has shown that a rapid living guidelines appro…
View article: Birth outcomes by type of attendance at antenatal education: An observational study
Birth outcomes by type of attendance at antenatal education: An observational study Open
Background Antenatal education aims to prepare expectant parents for pregnancy, birth, and parenthood. Studies have reported antenatal education teaching breathing and relaxation methods for pain relief, termed psychoprophylaxis, is associ…
View article: Clinician views and experiences of non‐invasive prenatal genetic screening tests in Australia
Clinician views and experiences of non‐invasive prenatal genetic screening tests in Australia Open
Background Non‐invasive prenatal screening (NIPS) is being increasingly used by expectant parents. Much provision of this test in Australia is occurring in clinical settings where specialised genetic counselling is unavailable, such as gen…
View article: eLearning significantly improves maternity professionals’ knowledge of the congenital cytomegalovirus prevention guidelines
eLearning significantly improves maternity professionals’ knowledge of the congenital cytomegalovirus prevention guidelines Open
Aims Cytomegalovirus (CMV) is a preventable cause of neurodevelopmental disability. Australian guidelines recommend that pregnant women are informed about CMV to reduce their risk of infection; however, less than 10% of maternity health pr…
View article: 319Congenital cytomegalovirus education, translation and prevention
319Congenital cytomegalovirus education, translation and prevention Open
Focus of Presentation Congenital cytomegalovirus (CMV) is a known cause of sensorineural hearing loss, cerebral palsy and other disabilities. International consensus guidelines (2017) and the Australasian Society of Infectious Diseases (20…