A. Sirek
YOU?
Author Swipe
View article: An Ex Vivo Model of Intervertebral Disc Degeneration for Assessing Retention of Injectable Cell‐Based Grafts
An Ex Vivo Model of Intervertebral Disc Degeneration for Assessing Retention of Injectable Cell‐Based Grafts Open
Introduction Cell therapies for painful intervertebral disc (IVD) degeneration (IDD) have not yet achieved widespread clinical adoption. Understanding therapeutic cell effects in native IVD remains challenging due to the complex IVD enviro…
View article: Relationship Between Thyroid Dysfunction and Ovarian Cancer
Relationship Between Thyroid Dysfunction and Ovarian Cancer Open
This review looks at the causes of the association between thyroid dysfunction (hyperthyroidism and hypothyroidism) and ovarian cancer (OC) risk. Epidemiological data have revealed that thyroid dysfunction, particularly hyperthyroidism, is…
View article: Systematic review of the effectiveness of standalone passive countermeasures on microgravity-induced physiologic deconditioning
Systematic review of the effectiveness of standalone passive countermeasures on microgravity-induced physiologic deconditioning Open
A systematic review of literature was conducted to evaluate the effectiveness of passive countermeasures in ameliorating the cardiopulmonary and musculoskeletal effects of gravitational unloading on humans during spaceflight. This systemat…
View article: Building a One Country One Licensure Framework: Applications for the Future of Canadian Space Physicians
Building a One Country One Licensure Framework: Applications for the Future of Canadian Space Physicians Open
Space medicine provides care in the most extreme environment known to humankind. The global space economy is forecast to be a $1 trillion industry by 2040. Its increased utilization will require additional legal healthcare support framewor…
View article: Immersive Extended Reality use in Medical Education with Implications for Remote and Space Medicine Training
Immersive Extended Reality use in Medical Education with Implications for Remote and Space Medicine Training Open
Objective: Medical education continually adapts and evolves as evidence-based practice expands our knowledge. Ease of access and reduced cost of novel technology has revolutionized delivery of medical education. Immersive extended reality …
View article: Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression
Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression Open
Insulin can stimulate hepatic expression of carbohydrate-responsive element-binding protein (ChREBP). As recent studies revealed potential metabolic beneficial effects of ChREBP, we asked whether its expression can also be regulated by the…