Jonatan Snir
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View article: Diagnostic CT-Enabled Planning (DART): Results of a Randomized Trial in Palliative Radiation Therapy
Diagnostic CT-Enabled Planning (DART): Results of a Randomized Trial in Palliative Radiation Therapy Open
dCT-based radiation planning substantially reduced TIC without detriment in plan deliverability or quality and had a tangible impact on patient experience with reduced patient-reported time burden.
View article: A power Doppler ultrasound method for improving intraoperative tip localization for visually obstructed needles in interstitial prostate brachytherapy
A power Doppler ultrasound method for improving intraoperative tip localization for visually obstructed needles in interstitial prostate brachytherapy Open
Purpose High‐dose‐rate (HDR) interstitial brachytherapy (BT) is a common treatment technique for localized intermediate to high‐risk prostate cancer. Transrectal ultrasound (US) imaging is typically used for guiding needle insertion, inclu…
View article: Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer’s Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [<sup>68</sup>Ga]Ga-TC3-OGDOTA
Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer’s Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [<sup>68</sup>Ga]Ga-TC3-OGDOTA Open
Apoptosis is a feature of stroke and Alzheimer’s disease (AD), yet there is no accepted method to detect or follow apoptosis in the brain in vivo. We developed a bifunctional tracer [ 68 Ga]Ga-TC3-OGDOTA containing a cell-penetrating pepti…
View article: P3‐239: Asymmetrically Low White Matter Integrity in Seniors with Mci and POOR GAIT
P3‐239: Asymmetrically Low White Matter Integrity in Seniors with Mci and POOR GAIT Open
Magnetic resonance diffusion tensor imaging (DTI) allows brain asymmetry to be studied at microscopic scale by examining differences in fiber characteristics across hemispheres. Recent studies demonstrated white matter (WM) asymmetry in he…
View article: O1‐02‐05: A novel positron emission tomography contrast agent targeting cathepsin d shows preferential <i>in vivo</i> retention in an Alzheimer's disease mouse model
O1‐02‐05: A novel positron emission tomography contrast agent targeting cathepsin d shows preferential <i>in vivo</i> retention in an Alzheimer's disease mouse model Open
Early detection of Alzheimer's disease (AD) pathology remains a serious challenge for both diagnosis and development of treatment. Cathepsin D (CatD), a lysosomal aspartyl protease, is over-expressed in AD and therefore is a potential biom…
View article: The Development and Validation of a Molecular Imaging Probe Targeted to Cathepsin D for the In-vivo Detection of Alzheimer Disease
The Development and Validation of a Molecular Imaging Probe Targeted to Cathepsin D for the In-vivo Detection of Alzheimer Disease Open
Background: Currently there is no widely accepted test to diagnose AD. The involvement of the lysosomal system in Alzheimer’s disease (AD) progression provides an opportunity to develop associated biomarkers. The lysosomal enzyme Cathepsin…