Aleksander Talerman
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View article: Malignant granulosa cell tumor of the testis associated with gynecomastia and long survival
Malignant granulosa cell tumor of the testis associated with gynecomastia and long survival Open
A case is reported of classic granulosa cell tumor of the testis with metastases to the retroperitoneal lymph nodes occurring in a 26-year-old man. The patient had left-sided testicular enlargement and bilateral gynecomastia. He was treate…
View article: True hermaphrodite with bilateral ovotestes, bilateral gonadoblastomas and dysgerminomas, 46, XX/46, XY karyotype, and a successful pregnancy
True hermaphrodite with bilateral ovotestes, bilateral gonadoblastomas and dysgerminomas, 46, XX/46, XY karyotype, and a successful pregnancy Open
The first case (to the authors' knowledge) is reported of a true hermaphrodite with bilateral ovotestes, bilateral gonadoblastomas and dysgerminomas, a 46, XX/46,XY karyotype, and a successful pregnancy. The true hermaphroditism was diagno…
View article: Mixed germ cell–sex cord stroma tumor of the testis. A report with ultrastructural findings
Mixed germ cell–sex cord stroma tumor of the testis. A report with ultrastructural findings Open
The case of a 41-year-old man with testicular mixed germ cell-sex cord stroma tumor is reported. The patient noticed a gradual, painless, right-sided testicular enlargement 4 years before being treated by radical orchiectomy. The testis co…
View article: Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide in the treatment of small cell carcinoma of the ovary
Vinblastine, cisplatin, cyclophosphamide, bleomycin, doxorubicin, and etoposide in the treatment of small cell carcinoma of the ovary Open
This report presents five adolescent girls and adult women with small cell carcinoma of the ovary (SCCO) who were treated with a polychemotherapy regimen consisting of vinblastine, cisplatin, cyclophosphamide, bleomycin, Adriamycin (doxoru…
View article: Adenocarcinoma of the rete testis with a spindle cell component. A possible metaplastic carcinoma
Adenocarcinoma of the rete testis with a spindle cell component. A possible metaplastic carcinoma Open
A case of adenocarcinoma of the rete testis was encountered in a 36-year-old white man. The tumor fulfilled established criteria for determining origin in the rete and showed an unusual biphasic morphology with papillary adenocarcinoma mix…
View article: Endodermal sinus tumor and mucinous cystadenofibroma of the ovary: Occurrence in an 82-year-old woman
Endodermal sinus tumor and mucinous cystadenofibroma of the ovary: Occurrence in an 82-year-old woman Open
We encountered an unusual ovarian tumor consisting of a mixture of typical endodermal sinus tumor (EST) and mucinous cystadenofibroma that occurred in the ovary of an 82-year-old female patient. The EST component showed the classic histolo…
View article: Ovarian Sertoli–Leydig cell tumor (androblastoma) with retiform pattern. A clinicopathologic study
Ovarian Sertoli–Leydig cell tumor (androblastoma) with retiform pattern. A clinicopathologic study Open
The clinicopathologic findings in nine patients with ovarian Sertoli-Leydig cell tumor with retiform pattern are described. The patients ranged in age from 11 months to 23 years; and seven patients were 12 years of age or younger. The most…
View article: A stromal leydig cell tumor of the ovary occurring in a pregnant 15-year-old girl. Ultrastructural findings
A stromal leydig cell tumor of the ovary occurring in a pregnant 15-year-old girl. Ultrastructural findings Open
The first case of stromal Leydig cell tumor of the ovary occurring during pregnancy is reported. A 15-year-old girl presented in labor at 36.5 weeks of gestation. The tumor mass was obstructing labor and the patient had to be delivered by …
View article: Serum alphafetoprotein (AFP) in diagnosis and management of endodermal sinus (yolk sac) tumor and mixed germ cell tumor of the ovary
Serum alphafetoprotein (AFP) in diagnosis and management of endodermal sinus (yolk sac) tumor and mixed germ cell tumor of the ovary Open
Serum AFP was determined serially by radioimmunoassay in 13 patients with ovarian germ cell tumors and in one patient with bilateral pure gonadoblastoma. There were 4 patients with pure dysgerminoma, one with pure endodermal sinus tumor (E…
View article: A mixed germ cell-sex cord stroma tumor of the ovary associated with isosexual precocious puberty in a normal girl
A mixed germ cell-sex cord stroma tumor of the ovary associated with isosexual precocious puberty in a normal girl Open
A case of mixed germ cell-sex cord stroma tumor occurring in a normal 8-year-old girl with 46XX karyotype is reported. The child presented with evidence of isosexual precocious puberty 3 years prior to the excision of the tumor. Although t…
View article: The incidence of yolk sac tumor (endodermal sinus tumor) elements in germ cell tumors of the testis in adults
The incidence of yolk sac tumor (endodermal sinus tumor) elements in germ cell tumors of the testis in adults Open
The incidence of yolk sac tumor (endodermal sinus tumor) elements was studied in 147 germ cell neoplasms of the testis in adults observed over a 4 1/2-year period. Excluding 79 cases of pure seminoma, yolk sac tumor elements were found in …
View article: Alpha-fetoprotein and germ cell tumors: A possible role of yolk sac tumor in production of alpha-fetoprotein
Alpha-fetoprotein and germ cell tumors: A possible role of yolk sac tumor in production of alpha-fetoprotein Open
Serum alpha-fetoprotein (αFP) was determined in 48 patients with germ cell tumors of the testis, ovary, and extragonadal sites. Thirty-four patients had evidence of active disease, while 14 patients were in remission. None of the latter ha…
View article: Yolk SAC tumor associated with seminoma of the testis in adults
Yolk SAC tumor associated with seminoma of the testis in adults Open
Three cases of yolk sac tumor of the testis combined with seminoma in adults are described. One patient died with widespread metastatic disease 4 months after orchidectomy. There was no response to chemotherapy. The other two patients, who…
View article: A distinctive gonadal neoplasm related to gonadoblastoma
A distinctive gonadal neoplasm related to gonadoblastoma Open
A distinctive gonadal neoplasm composed of germ cells and sex cord stroma derivatives (primitive Sertoli and granulosa cells) intimately mixed together throughout, forming a cord-like, or trabecular pattern is described. In addition to the…
View article: Congenital mitral atresia.
Congenital mitral atresia. Open
Mitral atresia is a rare congenital anomaly, but its true incidence is difficult to assess.In 1962, Fontana and Edwards reported 8 cases of isolated mitral atresia and found 24 others in published reports.They also described 5 cases of com…