I. A. Yatskov
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View article: Application of dry carbon dioxide baths and magnetotherapy in the treatment of patients during the post COVID period
Application of dry carbon dioxide baths and magnetotherapy in the treatment of patients during the post COVID period Open
Aim . To study the effect of dry carbon dioxide baths (DCB) and magnetotherapy (MT) on quality-oflife indicators, dyspnoea severity, psychological status and systemic inflammation in patients who had recovered from novel coronavirus infect…
View article: Imbalance of endotoxin-binding systems in patients with type 1 diabetes
Imbalance of endotoxin-binding systems in patients with type 1 diabetes Open
Rationale . The number of patients with type 1 diabetes mellitus (DM1) in the Russian Federation is 277.1 thousand people, and this number continues to grow. Disturbance of glycemia leads to the development of oxidative stress and damage t…
View article: Influence of health resort treatment combined with grape polyphenol concentrate on lipid profile and systemic inflammation markers in patients with asthma during the post-COVID period
Influence of health resort treatment combined with grape polyphenol concentrate on lipid profile and systemic inflammation markers in patients with asthma during the post-COVID period Open
Aim. To assess the effect of health resort treatment combined with grape polyphenols on lipid metabolism and systemic inflammation markers in patients with asthma after COVID-19. Materials and methods. Patients with asthma and a history of…
View article: Effects of TGF-b Arg25Pro polymorphism on the markers of systemic inflammation, intestinal permeability, and vascular regulation in patients with bronchial asthma during post-COVID period
Effects of TGF-b Arg25Pro polymorphism on the markers of systemic inflammation, intestinal permeability, and vascular regulation in patients with bronchial asthma during post-COVID period Open
The condition of patients following new coronavirus infection (NCI) is accompanied by a number of pathophysiologic changes that aggravate the course of the patient’s existing pathology, which is especially manifesting by cardiovascular and…
View article: Overview of the prevalence and features of oncological diseases in type 2 diabetes and possible immunological mechanisms
Overview of the prevalence and features of oncological diseases in type 2 diabetes and possible immunological mechanisms Open
Worldwide, the number of patients with diabetes has quadrupled over the past three decades. Every eleventh adult is currently diagnosed with diabetes mellitus, 90% of which are type 2 diabetes mellitus (DM2). Generally recognized complicat…
View article: Effect of phytocomposition on dyslipidemia in patients with SARS-CoV-2 infection at the health resort stage of treatment
Effect of phytocomposition on dyslipidemia in patients with SARS-CoV-2 infection at the health resort stage of treatment Open
Background . Cardiovascular events are the main threat in the post-COVID period, and their risk is increased in patients who have had a new coronavirus infection (SARS-CoV-2). In this regard, the direction of studying the correction of alr…
View article: Modern approaches to the rehabilitation of patients with respiratory diseases
Modern approaches to the rehabilitation of patients with respiratory diseases Open
Breathing exercises are widely used worldwide as a non-drug therapy of respiratory diseases. Pulmonary rehabilitation is a proven and effective intervention for individuals with chronic respiratory diseases. Traditionally, pulmonary rehabi…
View article: Rehabilitation Experience in Patients with Post-COVID Syndrome
Rehabilitation Experience in Patients with Post-COVID Syndrome Open
A large number of patients with new coronavirus infection at high risk of developing post – COVID syndrome. Therefore, most patients will certainly require rehabilitation to mitigate the effect of this syndrome. Objective. The primary obje…
View article: Clinical and Laboratory Characteristics of Patients with Bronchial Asthma who Suffered from COVID-19
Clinical and Laboratory Characteristics of Patients with Bronchial Asthma who Suffered from COVID-19 Open
Aim. To identify differences in the clinical and laboratory profile of patients with bronchial asthma (BA) who suffered a clinically significant coronavirus infection caused by the SARS-Cov2 virus and patients with asthma, without anamnest…
View article: The role of Toll-like receptor 4 Asp299Gly genetic polymorphism in rehabilitation of patients with post-COVID syndrome
The role of Toll-like receptor 4 Asp299Gly genetic polymorphism in rehabilitation of patients with post-COVID syndrome Open
Introduction. The multivariability of the clinical course of post-covid syndrome (PCS) is associated with genetic heterogeneity of the population, which leads to a high interest in the study of genotypes. Aim. To evaluate the role of Toll-…
View article: Using essential oils in rehabilitation of olfactory disorders in patients who have had a new coronavirus infection
Using essential oils in rehabilitation of olfactory disorders in patients who have had a new coronavirus infection Open
Background . SARS-CoV-2 infection often results in olfactory disorder at different levels of the nervous system, which may persist as anosmia, parosmia, hyperosmia, hyposmia, cacosmia, and olfactory hallucinations after recovery. The aim .…
View article: Effect of IL-2 T-330G polymorphism on markers of systemic inflammation, intestinal permeability and vascular regulation in post-COVID patients
Effect of IL-2 T-330G polymorphism on markers of systemic inflammation, intestinal permeability and vascular regulation in post-COVID patients Open
Recent studies suggest a role of genetic factors, i.e., polymorphisms of genes controlling the main immune components of antiviral response, and the risk of COVID-19 infection, severe course and lethal outcomes of the disease, as well as d…
View article: Imbalance of lipopolysaccharide-binding systems as a potential link in pathogenesis of rheumatoid arthritis
Imbalance of lipopolysaccharide-binding systems as a potential link in pathogenesis of rheumatoid arthritis Open
Lipopolysaccharide (LPS, endotoxin) of Gram-negative bacteria is a strong activator of innate immune system and inducer of systemic and local inflammation. Due to increasing number of factors contributing to the translocation of LPS into t…
View article: Low-grade systemic inflammation in patients with long COVID: The role of imbalance of endotoxin-releasing systems and vasoconstrictor markers
Low-grade systemic inflammation in patients with long COVID: The role of imbalance of endotoxin-releasing systems and vasoconstrictor markers Open
Background. Currently, the pathophysiological mechanisms of acute damage to organs and systems caused by coronavirus infection have been studied quite fully, but the mechanisms underlying the clinical manifestations of long COVID have not …
View article: CD14 gene polymorphism in COVID-19 convalescents: analysis of (C-159)T
CD14 gene polymorphism in COVID-19 convalescents: analysis of (C-159)T Open
Cluster of differentiation 14 (CD14) is a pattern recognition receptor for lipopolysaccharide of gram-negative flora and has a close relationship with toll-like receptor 4 (TLR4). The interaction between CD14 and TLR 4 leads to the synthes…
View article: Frequency of polymorphism of the <i>C-589T IL4</i> and <i>G-1082A IL10</i> genes in children with new coronavirus infection
Frequency of polymorphism of the <i>C-589T IL4</i> and <i>G-1082A IL10</i> genes in children with new coronavirus infection Open
Immune responses are involved in the initiation and development of COVID-19. Compared with mild COVID-19 cases, serum interleukins levels were significantly increased in severe and critical COVID-19 patients. Increases in IL-4 and IL-10 ar…
View article: Syndrome of increased intestinal permeability in type 1 and type 2 diabetes mellitus
Syndrome of increased intestinal permeability in type 1 and type 2 diabetes mellitus Open
Diabetes mellitus is a chronic disease that requires lifelong medical supervision. Hundreds of millions of people around the world and the rapidly increasing incidence of diabetes are a heavy burden on the health system. Over the past deca…
View article: Prospects for the use of polyphenols in patients with bronchial asthma and obesity
Prospects for the use of polyphenols in patients with bronchial asthma and obesity Open
Asthma and obesity are diseases characterized by variability in the course and possible complications, the frequency of which is steadily increasing from year to year. The correlation between obesity and asthma is still an acute problem of…
View article: Low-grade inflammation in the post-COVID period as a strategic goal of treatment and rehabilitation
Low-grade inflammation in the post-COVID period as a strategic goal of treatment and rehabilitation Open
As of the beginning of 2023, there are more than 660 million convalescents of a new coronavirus infection in the world, however, even despite successful treatment of the acute period of the disease, such patients have a high risk of develo…
View article: Difficulties in the Diagnosis and Management of Patients with Takayasu’s Arteritis: A Description of a 5-Year Clinical Follow-Up
Difficulties in the Diagnosis and Management of Patients with Takayasu’s Arteritis: A Description of a 5-Year Clinical Follow-Up Open
Takayasu’s disease (nonspecific aortoarteritis) is a granulomatous inflammation of the aorta and its main branches with a progressive course and development of severe ischemic disorders. The difficulty of diagnosis and the possibility of a…
View article: Role of Toll-like receptor gene polymorphism in pathogenesis of new coronavirus infection
Role of Toll-like receptor gene polymorphism in pathogenesis of new coronavirus infection Open
The review article contains data from literature which concern the role of Toll-like receptors (TLRs), immune sensors that play a key role in the systemic response to both bacterial and viral infections, e.g., in pathogenesis of a new coro…
View article: Role of lipopolysaccharide in genesis of microvascular complications in type 1 diabetes mellitus
Role of lipopolysaccharide in genesis of microvascular complications in type 1 diabetes mellitus Open
Despite significant advances in pathogenetic treatments for patients with diabetes mellitus type 1 (DM1) and reduction of mortality in this cohort of patients, as compared with general population, the difference in life expectancy in DM1 p…
View article: Influence of health resort treatment on the level of systemic inflammation in patients after new coronavirus infection
Influence of health resort treatment on the level of systemic inflammation in patients after new coronavirus infection Open
Background. Low-grade inflammation is currently one of the main risk factors for the development of adverse events in the cardiovascular system, including death from cardiovascular diseases or their complications that cause mortality in th…
View article: Some Features of Laboratory Parameters in Patients with SARS-CoV-2 with Underlying Overweight and Obesity
Some Features of Laboratory Parameters in Patients with SARS-CoV-2 with Underlying Overweight and Obesity Open
INTRODUCTION: The data of SARS-CoV-2 pandemic studies indicate a pronounced influence of overweight and obesity on the course of the new coronavirus infection and the risk of lethal complications. In this regard, of particular interest are…
View article: Features of the frequency of occurrence of T-330G <i>IL2</i> gene polymorphism in patients with COVID-19
Features of the frequency of occurrence of T-330G <i>IL2</i> gene polymorphism in patients with COVID-19 Open
SARS-CoV-2 infection is the etiopathogenetic factor of the new coronavirus infection. Susceptibility to the virus and, accordingly, the incidence differs in children and adults. On the one hand, this reflects the age-related features of th…
View article: Post-vaccination and post-infectious immune response against new coronavirus infection on the background of obesity and overweight
Post-vaccination and post-infectious immune response against new coronavirus infection on the background of obesity and overweight Open
In the fall of 2019, global health was confronted with a new RNA virus — severe acute respiratory syndrome coronavirus 2 SARS-CoV-2. Against the background of the rapid spread of infection, research centers around the world began to develo…