Alison R. Yung
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View article: Can a digital intervention ‘Momentum’ improve social functioning and transdiagnostic symptoms for Australian youth at ultrahigh risk for psychosis? Protocol for a superiority randomised controlled trial comparing treatment as usual with and without Momentum
Can a digital intervention ‘Momentum’ improve social functioning and transdiagnostic symptoms for Australian youth at ultrahigh risk for psychosis? Protocol for a superiority randomised controlled trial comparing treatment as usual with and without Momentum Open
Introduction Existing psychological and pharmacological interventions for young people at ultra-high risk (UHR) for psychosis have shown benefit in at least delaying the transition to psychosis, but they have limited benefit for comorbid d…
View article: Silver Nanoparticles Templated by the M13 Phage Exhibit High Antibacterial Activity against Gram-Negative Pathogens and a Reduced Rate of Bacterial Resistance In Vitro
Silver Nanoparticles Templated by the M13 Phage Exhibit High Antibacterial Activity against Gram-Negative Pathogens and a Reduced Rate of Bacterial Resistance In Vitro Open
Silver and silver nanoparticles (AgNPs) are well-known for their antibacterial properties. However, their low potency and the emergence of resistance are major barriers to the use of AgNPs in systemic therapy. Biological products can be us…
View article: Exploring the interconnections between baseline symptoms in ultra-high risk youth who did and did not transition to psychosis over three years: A network analysis comparison
Exploring the interconnections between baseline symptoms in ultra-high risk youth who did and did not transition to psychosis over three years: A network analysis comparison Open
Background In the ultra-high risk for psychosis (UHR) field, it is unknown whether understanding symptom relationships, beyond symptom severity alone, may hold prognostic value and inform preventive care. In this study, network analysis wa…
View article: Health service experiences of LGBTQA+ adults in Australia with psychotic disorders, common mental disorders and physical health conditions: Findings from the <i>Private Lives 3</i> national survey
Health service experiences of LGBTQA+ adults in Australia with psychotic disorders, common mental disorders and physical health conditions: Findings from the <i>Private Lives 3</i> national survey Open
Background: Lesbian, gay, bisexual, transgender, queer or questioning, asexual or aromantic and more (LGBTQA+) populations face disparities in health outcomes, which are particularly pronounced in relation to mental health. While psychotic…
View article: Sharing and reuse of mental health research data: Introducing the HeSANDA mental health node
Sharing and reuse of mental health research data: Introducing the HeSANDA mental health node Open
Introduction Data sharing is the practice of making de-identified participant-level data available for use by other researchers. It increases the potential of a dataset to answer new questions, accelerates knowledge creation and increases …
View article: Metagenome-inspired libraries to engineer phage M13 for targeted killing of Gram-negative bacterial species
Metagenome-inspired libraries to engineer phage M13 for targeted killing of Gram-negative bacterial species Open
Given concerning trends in antibiotic resistance, phages have been increasingly explored as promising antimicrobial agents. However, a major problem with phage therapy is the overly high specificity of phages for their hosts, which is curr…
View article: Addressing the unmet needs of bipolar disorder in Australia and beyond
Addressing the unmet needs of bipolar disorder in Australia and beyond Open
People impacted by bipolar disorder are confronted by many unmet needs that contribute to the overall burden associated with the disorder. We do not have a good understanding of the underlying pathology of bipolar disorder, so we do not ha…
View article: Association between non-adherence to fish oil or placebo as a risk factor of transition to psychosis in ultra-high-risk individuals in the NEURAPRO study
Association between non-adherence to fish oil or placebo as a risk factor of transition to psychosis in ultra-high-risk individuals in the NEURAPRO study Open
Objective: Non-adherence is an important factor in clinical trials, which has not been investigated in people at ultra-high risk (UHR) of developing a first episode of psychosis. Methods: Exploratory analysis of data from NEURAPRO, a multi…
A Synthetic Phage-Peptide Conjugate as a Potent Antibacterial Agent for <i>Pseudomonas aeruginosa</i> Infections Open
Antibiotic resistance among Gram-negative organisms is a major challenge. Some molecules, including antimicrobial peptides such as polymyxin B (PMB), are antibacterial but toxic due to low specificity, causing poor clinical utility. Drug d…
View article: Clinical characteristics associated with persistent and emerging eating disorder risk in young people presenting for mental health care
Clinical characteristics associated with persistent and emerging eating disorder risk in young people presenting for mental health care Open
Eating disorders (EDs) are serious mental health conditions with peak onset during adolescence and young adulthood. While early intervention services frequently encounter young people at-risk of EDs, little is known about the trajectories …
View article: A protocol for population-level data linkage to investigate patterns of service use and health care needs of young people experiencing mental ill-health in Victoria Australia
A protocol for population-level data linkage to investigate patterns of service use and health care needs of young people experiencing mental ill-health in Victoria Australia Open
Introduction: Mental disorders are a leading cause of disease burden in 10-24-year-olds. In Australia, fragmentation within and across sectors (health, mental health and human services) results in gaps in service provision and increases th…
View article: An Effectiveness Trial of an Exercise Physiologist Service to Improve Quality of Life in Adults with Severe Mental Illness: Protocol for the MOVEMENT Study
An Effectiveness Trial of an Exercise Physiologist Service to Improve Quality of Life in Adults with Severe Mental Illness: Protocol for the MOVEMENT Study Open
The trial is registered under the Australian and New Zealand Clinical Trial Registry (ACTRN12624001148561).
View article: An Effectiveness Trial of an Exercise Physiologist Service to Improve Quality of Life in Adults with Severe Mental Illness: Protocol for the MOVEMENT Study [Corrigendum]
An Effectiveness Trial of an Exercise Physiologist Service to Improve Quality of Life in Adults with Severe Mental Illness: Protocol for the MOVEMENT Study [Corrigendum] Open
[This corrects the article DOI: 10.2147/NDT.S530837.].
View article: Healthy Smiles: Promoting Good Oral Health for Youth With Serious Mental Illness
Healthy Smiles: Promoting Good Oral Health for Youth With Serious Mental Illness Open
Background Individuals with serious mental illness (SMI) are disproportionally affected by oral diseases, contributing to already poor physical health outcomes. Young adults are particularly vulnerable, with high psychological distress and…
View article: Using data linkage for mental health research in Australia
Using data linkage for mental health research in Australia Open
Data linkage is a powerful tool for understanding the multifaceted needs and priorities of mental health care from the perspective of users and providers. Its potential remains underutilised in Australian settings – the Productivity Commis…
View article: Multidimensional outcomes associated with chronic fatigue over 12 months in youth with emerging mood disorders
Multidimensional outcomes associated with chronic fatigue over 12 months in youth with emerging mood disorders Open
Chronic fatigue was common and associated with poorer mental health and functioning longitudinally. While there were no sex differences in the rates of chronic fatigue, there were some sex differences in the factors associated with it. Sys…
Sol-gel synthesized V2O5/TiO2 catalysts for NH3-SCR: Effect of calcination temperature on performance Open
Ammonia-based selective catalytic reduction (SCR) is essential for removing nitrogen oxides (NOX) emitted from industrial furnaces and automobiles. Although commercial V2O5/TiO2 catalysts are economically viable for NH3-SCR, their poor cat…
Substance use patterns among youth seeking help for mental illness: A latent class analysis Open
Findings identify clinically-significant substance use patterns among youth accessing mental health care, with implications for development of early interventions to address substance use in this risk-enriched population.
View article: Sample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program
Sample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program Open
Clinical ascertainment and clinical outcome are key features of any large multisite study. In the ProNET and PRESCIENT research networks, the Accelerating Medicines Partnership® Schizophrenia (AMP®SCZ) Clinical Ascertainment and Outcome Me…
View article: A protocol for population-level data linkage to investigate patterns of service use and health care needs of young people experiencing mental ill-health in Victoria Australia
A protocol for population-level data linkage to investigate patterns of service use and health care needs of young people experiencing mental ill-health in Victoria Australia Open
Introduction: Mental disorders are a leading cause of disease burden in 10-24-year-olds. In Australia, fragmentation within and across sectors (health, mental health and human services) results in gaps in service provision and increases th…
View article: Activation differentiates illness trajectories among youth seeking mental health care
Activation differentiates illness trajectories among youth seeking mental health care Open
These findings suggest that activation is a marker of poorer clinical and functional outcomes in youth presenting for mental health care.
View article: A protocol for population-level data linkage to investigate patterns of service use and health care needs of young people from Victoria Australia experiencing mental ill-health
A protocol for population-level data linkage to investigate patterns of service use and health care needs of young people from Victoria Australia experiencing mental ill-health Open
Introduction: Mental disorders are diverse, complex, multifaceted, and co-morbidity is common. They are a leading cause of disease burden in 10–24-year-olds. In Australia, fragmentation within and across sectors (health, mental health and …
View article: Clinical prediction model for transition to psychosis in individuals meeting At Risk Mental State criteria
Clinical prediction model for transition to psychosis in individuals meeting At Risk Mental State criteria Open
Background The At Risk Mental State (ARMS) (also known as the Ultra or Clinical High Risk) criteria identify individuals at high risk for psychotic disorder. However, there is a need to improve prediction as only about 18% of individuals m…