Aarif O. Eifan
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View article: Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy
Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy Open
View article: Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy
Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy Open
View article: Altered chromatin landscape in circulating T follicular helper and regulatory cells following grass pollen subcutaneous and sublingual immunotherapy
Altered chromatin landscape in circulating T follicular helper and regulatory cells following grass pollen subcutaneous and sublingual immunotherapy Open
View article: Allergen Immunotherapy in Children User’s Guide
Allergen Immunotherapy in Children User’s Guide Open
Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and downplaying the immune response induced by allergens. Cl…
View article: Nasal allergen-neutralizing IgG4 antibodies block IgE-mediated responses: Novel biomarker of subcutaneous grass pollen immunotherapy
Nasal allergen-neutralizing IgG4 antibodies block IgE-mediated responses: Novel biomarker of subcutaneous grass pollen immunotherapy Open
View article: Duration of Allergen Immunotherapy for Long-Term Efficacy in Allergic Rhinoconjunctivitis
Duration of Allergen Immunotherapy for Long-Term Efficacy in Allergic Rhinoconjunctivitis Open
The data presented here support recommendations in international guidelines that both routes of administration should be continued for a minimum of 3 years. Gaps in the evidence remain regarding the long-term efficacy of immunotherapy for …
View article: Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis
Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis Open
clinicaltrials.gov Identifier: NCT01335139; EudraCT Number: 2010-023536-16.
View article: Response to Nasal Challenge Correlates with Seasonal Outcomes during Grass Pollen Immunotherapy with Either Subcutaneous or Sublingual Immunotherapy
Response to Nasal Challenge Correlates with Seasonal Outcomes during Grass Pollen Immunotherapy with Either Subcutaneous or Sublingual Immunotherapy Open
View article: Altered TGF-Î2 Signalling in Inflammatory Nasal Polyps Drive Remodelling in Crswnp
Altered TGF-Î2 Signalling in Inflammatory Nasal Polyps Drive Remodelling in Crswnp Open
View article: Randomised Placebo-Controlled Trial of Grass Pollen Allergen Tablet Immunotherapy for Seasonal Rhinitis: Clinical and Surrogate Outcomes and Early Time Course of Immunologic Changes
Randomised Placebo-Controlled Trial of Grass Pollen Allergen Tablet Immunotherapy for Seasonal Rhinitis: Clinical and Surrogate Outcomes and Early Time Course of Immunologic Changes Open
View article: Effect of grass pollen immunotherapy on clinical and local immune response to nasal allergen challenge
Effect of grass pollen immunotherapy on clinical and local immune response to nasal allergen challenge Open
Nasal allergen challenge is sensitive in the detection of clinical and biological effects of allergen immunotherapy and may be a useful surrogate marker of treatment efficacy in future studies.
View article: Protocol for a randomised, double‐blind, placebo‐controlled study of grass allergen immunotherapy tablet for seasonal allergic rhinitis: time course of nasal, cutaneous and immunological outcomes
Protocol for a randomised, double‐blind, placebo‐controlled study of grass allergen immunotherapy tablet for seasonal allergic rhinitis: time course of nasal, cutaneous and immunological outcomes Open
Background Seasonal Allergic Rhinitis is characterised by inflammation of the nasal mucosa upon exposure to common aeroallergens, affecting up to 20–25 % of the population. For those patients whose symptoms are not controlled by standard m…