Kyungwon Lee
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View article: Increasing Antimicrobial Resistance Profile Diversity of Colonizing Group B <i>Streptococcus</i> in Reproductive-aged Women in Korea
Increasing Antimicrobial Resistance Profile Diversity of Colonizing Group B <i>Streptococcus</i> in Reproductive-aged Women in Korea Open
The acquisition of diverse resistance genes has expanded AMR profiles in colonized GBS, emphasizing the need for sustained nationwide surveillance.
View article: Incidental Findings on Abdominopelvic CT in Young Korean Soldiers: Prevalence, Clinical Relevance, and Healthcare System Implications
Incidental Findings on Abdominopelvic CT in Young Korean Soldiers: Prevalence, Clinical Relevance, and Healthcare System Implications Open
Background: This retrospective case series examines incidental findings (IFs) detected on abdominopelvic CT (APCT) among young Korean soldiers presenting with acute abdominal pain. APCT is a frontline test for acute abdominal pain but freq…
View article: Characterization of Antimicrobial Resistance and Hypervirulent Traits of Klebsiella variicola Isolates Collected in South Korea
Characterization of Antimicrobial Resistance and Hypervirulent Traits of Klebsiella variicola Isolates Collected in South Korea Open
Introduction: Klebsiella variicola, a member of Klebsiella pneumoniae complex, has emerged as an opportunistic pathogen for human infection; however, antimicrobial resistance and hypervirulent characteristics of K. variicola have rarely be…
View article: Harnessing Induced Pluripotent Stem Cells for Cardiac-Related Pain: Advances, Models, and Therapeutic Prospects
Harnessing Induced Pluripotent Stem Cells for Cardiac-Related Pain: Advances, Models, and Therapeutic Prospects Open
Cardiac pain is difficult to diagnose and treat in part because existing models fail to capture human neuro-cardiac signaling. This review examines how iPSC-derived cardiomyocytes and sensory neurons in co-culture and organoid systems mode…
View article: Incidental Findings on Abdominopelvic CT in Young Korean Soldiers: Prevalence, Clinical Relevance, and Healthcare System Implications
Incidental Findings on Abdominopelvic CT in Young Korean Soldiers: Prevalence, Clinical Relevance, and Healthcare System Implications Open
Background Abdominopelvic computed tomography (APCT) is a frontline diagnostic modality for acute abdominal pain, but it often reveals incidental findings (IFs) that are unrelated to the presenting complaint. While many IFs are benign, som…
View article: Carbapenem-Resistant <i>Citrobacter koseri</i>: An Emerging Concern in Long-term Care Hospital
Carbapenem-Resistant <i>Citrobacter koseri</i>: An Emerging Concern in Long-term Care Hospital Open
View article: <i>In-vitro</i> Activities of Zoliflodacin and Solithromycin Against <i>Neisseria gonorrhoeae</i> Isolates from Korea
<i>In-vitro</i> Activities of Zoliflodacin and Solithromycin Against <i>Neisseria gonorrhoeae</i> Isolates from Korea Open
Novel antimicrobial agents are continually developed to address the global threat of multidrug-resistant Neisseria gonorrhoeae. Promising candidates include zoliflodacin and, possibly, solithromycin. We evaluated their in-vitro
View article: Awareness and Usage of Domestic Food Nutrition Information Database Platforms
Awareness and Usage of Domestic Food Nutrition Information Database Platforms Open
View article: A Survey on Awareness and Usage of the Food Nutrition Information and Food Nutrition Information Database Platform by Age Group
A Survey on Awareness and Usage of the Food Nutrition Information and Food Nutrition Information Database Platform by Age Group Open
View article: Development of a Disease Modeling Framework for Glutamatergic Neurons Derived from Neuroblastoma Cells in 3D Microarrays
Development of a Disease Modeling Framework for Glutamatergic Neurons Derived from Neuroblastoma Cells in 3D Microarrays Open
Neurodegenerative diseases (NDDs) present significant challenges due to limited treatment options, ethical concerns surrounding traditional animal models, and the time-consuming and costly process of using human-induced pluripotent stem ce…
View article: Acceleration of Modeling Capability for GDI Spray by Machine-Learning Algorithms
Acceleration of Modeling Capability for GDI Spray by Machine-Learning Algorithms Open
Cold start causes a high amount of unburned hydrocarbon and particulate matter emissions in gasoline direct injection (GDI) engines. Therefore, it is necessary to understand the dynamics of spray during a cold start and develop a predictiv…
View article: Biochemical, structural, and single-molecule characterization of LIG1 active site mutants demonstrate role of F635 and F872 residues for faithful ligation
Biochemical, structural, and single-molecule characterization of LIG1 active site mutants demonstrate role of F635 and F872 residues for faithful ligation Open
Human DNA ligase 1 (LIG1) finalizes DNA repair pathways by an ultimate ligation step and discriminates against nicks containing unusual ends, yet the contribution of the conserved active site residues for faithful end joining remains unkno…
View article: Biosensor for integrin inhibition of mammalian cell adhesion and migration using micropatterned cell culture substrate and retroreflective optical signaling
Biosensor for integrin inhibition of mammalian cell adhesion and migration using micropatterned cell culture substrate and retroreflective optical signaling Open
Integrins are a family of transmembrane receptors that play a crucial role in cell adhesion and migration. Integrins can uniquely transduce biochemical signals bidirectionally across the membrane and physically link the cell-cell and cell-…
View article: Preclinical evaluation of NG101, a potential AAV gene therapy for wet age-related macular degeneration
Preclinical evaluation of NG101, a potential AAV gene therapy for wet age-related macular degeneration Open
View article: Clinically Probable Multiple System Atrophy Presenting Ptosis as an Early Manifestation
Clinically Probable Multiple System Atrophy Presenting Ptosis as an Early Manifestation Open
Many ocular features were found in patients with multiple system atrophy (MSA), which include dry eye, blepharospasm, eye movement problems, and blink reflex dysfunction. Some of these symptoms are associated with autonomic dysfunctions se…
View article: Clinical Outcomes and Molecular Characteristics of <i>Bacteroides fragilis</i> Infections
Clinical Outcomes and Molecular Characteristics of <i>Bacteroides fragilis</i> Infections Open
Bacteroides fragilis is the most common opportunistic anaerobic pathogen. In the absence of appropriate antimicrobial therapy, mortality rates associated with B. fragilis group infections can reach as high as 50%. Therefore, …
View article: Mutagenic ligation of polβ mismatch insertion products during 8-oxoG bypass by LIG1 and LIG3α at the downstream steps of base excision repair pathway
Mutagenic ligation of polβ mismatch insertion products during 8-oxoG bypass by LIG1 and LIG3α at the downstream steps of base excision repair pathway Open
Base excision repair (BER) maintains genome integrity by fixing oxidized bases that could be formed when reactive oxygen species attack directly on the DNA. We previously reported the importance of a proper coordination at the downstream s…
View article: Evaluation of the Disk Diffusion Test for <i>Bacteroides fragilis</i> Group Clinical Isolates
Evaluation of the Disk Diffusion Test for <i>Bacteroides fragilis</i> Group Clinical Isolates Open
The DDT can be a useful alternative antimicrobial susceptibility test for BFG isolates when using the ATU zone to reduce errors.
View article: <i>Pasteurella</i> Infections in South Korea and Systematic Review and Meta-analysis of <i>Pasteurella</i> Bacteremia
<i>Pasteurella</i> Infections in South Korea and Systematic Review and Meta-analysis of <i>Pasteurella</i> Bacteremia Open
Pasteurella spp. can cause fatal zoonotic infections in humans. We performed a multicenter study to investigate the prevalence and clinical features of Pasteurella infections in South Korea during 2018‒2022. We also conducted a collaborati…
View article: Reversible Lesion in the Splenium of the Corpus Callosum due to Thermogenic Dietary Supplements
Reversible Lesion in the Splenium of the Corpus Callosum due to Thermogenic Dietary Supplements Open
The use of thermogenic dietary supplements has led to growing concerns about potential adverse health effects. A 19-year-old female patient experienced recurrent blurred vision after consuming thermogenic dietary supplements for 5 weeks an…
View article: Prevalence and Molecular Characterization of Pharyngeal Gonorrhea in Korean Men With Urethritis
Prevalence and Molecular Characterization of Pharyngeal Gonorrhea in Korean Men With Urethritis Open
The prevalence of pharyngeal gonorrhea in Korean men with gonococcal urethritis is as high as 30.5%, highlighting the need for pharyngeal screening in high-risk groups. Ceftriaxone is the recommended treatment for pharyngeal gonorrhea.
View article: Anisotropic regularization for sparsely sampled and noise-robust Fourier ptychography
Anisotropic regularization for sparsely sampled and noise-robust Fourier ptychography Open
Fourier ptychography (FP) is a powerful computational imaging technique that provides super-resolution and quantitative phase imaging capabilities by scanning samples in Fourier space with angle-varying illuminations. However, the image re…
View article: Anti-Ma2 Paraneoplastic Cerebellar Degeneration Responding to Immunotherapy
Anti-Ma2 Paraneoplastic Cerebellar Degeneration Responding to Immunotherapy Open
View article: Quantitative Analysis of Integrin Inhibition of Mammalian Cells Utilizing Micropatterned Culture Substrate and Retroreflective Optical Sensing
Quantitative Analysis of Integrin Inhibition of Mammalian Cells Utilizing Micropatterned Culture Substrate and Retroreflective Optical Sensing Open
View article: Antihypertensive Effect of Milk Fermented by Lactiplantibacillus plantarum K79 on Spontaneously Hypertensive Rats
Antihypertensive Effect of Milk Fermented by Lactiplantibacillus plantarum K79 on Spontaneously Hypertensive Rats Open
The aim of this study is to investigate whether milk fermented by Lactiplantibacillus plantarum K79, which exhibits angiotensin-converting enzyme inhibitory activity, has an effect on lowering the blood pressure of hypertensive rats…
View article: Fuel temperature and injection pressure influence on the cold start GDI sprays
Fuel temperature and injection pressure influence on the cold start GDI sprays Open
Cold start in gasoline direct injection engines (GDI) is a critical issue that significantly impacts fuel consumption and emissions. Therefore, it is essential to investigate and improve the spray and air-fuel mixing processes during cold …
View article: Association of main meal frequency and skipping with metabolic syndrome in Korean adults: a cross-sectional study
Association of main meal frequency and skipping with metabolic syndrome in Korean adults: a cross-sectional study Open
Background Reduced meal frequency can increase the risk of metabolic syndrome (MetS). However, limited studies have examined the association between meal frequency and skipping meals with MetS. This study aims to analyze the association be…
View article: Deep computational microscopy via physics-informed end-to-end learning with a learned forward model
Deep computational microscopy via physics-informed end-to-end learning with a learned forward model Open
Computational microscopy, which merges cutting-edge optical methods with intricate algorithms, offers significant potential for applications such as resolution improvement and quantitative phase retrieval. However, it faces challenges due …
View article: Fusobacterium nucleatum induces a tumor microenvironment with diminished adaptive immunity against colorectal cancers
Fusobacterium nucleatum induces a tumor microenvironment with diminished adaptive immunity against colorectal cancers Open
Background & Aims Fusobacterium nucleatum (FN) plays a pivotal role in the development and progression of colorectal cancer by modulating antitumor immune responses. However, the impact of FN on immune regulation in the tumor microenvi…
View article: Risk factors and microbiological features of recurrent Escherichia coli bloodstream infections
Risk factors and microbiological features of recurrent Escherichia coli bloodstream infections Open
Understanding the risk factors and microbiological features in recurrent Escherichia coli BSI is helpful for clinicians. Data of patients with E . coil BSI from 2017 to 2018 were collected. Antimicrobial resistance rates of E . coli were d…