Aaron M. Rosado
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View article: Digital neuropathology of neurodegenerative disorders: Foundations, research advances, and future directions
Digital neuropathology of neurodegenerative disorders: Foundations, research advances, and future directions Open
A neuropathology examination after death remains the gold standard for differentiating between Alzheimer disease (AD) and AD and related dementias (ADRD). Increasing interest and familiarity with digital imaging highlights recent shifts to…
View article: Long‐Term Postoperative Donor Site Musculoskeletal Morbidity after Osseous Free Flap Harvest
Long‐Term Postoperative Donor Site Musculoskeletal Morbidity after Osseous Free Flap Harvest Open
Objective Complex ablative maxillary and mandibular defects often require osseous free flap reconstruction. Workhorse options include the fibula, scapula, and osteocutaneous radial forearm flap (OCRFF). The choice of donor site for harvest…
View article: Memory in repetitive protein–protein interaction series
Memory in repetitive protein–protein interaction series Open
Interactions between proteins coordinate biological processes in an organism and may impact its responses to changing environments and diseases through feedback systems. Feedback systems function by using changes in the past to influence b…
View article: Memory in Repetitive Protein–Protein Interaction Series – in Memory of the Late Professor Robert M. Nerem
Memory in Repetitive Protein–Protein Interaction Series – in Memory of the Late Professor Robert M. Nerem Open
Over the past three decades, the senior author had interacted with and been mentored by the late Professor Robert M. Nerem. In his memory, the authors summarized several observations made, ideas conceptualized, and mathematical models deve…
View article: Localized hydrogel delivery of dendritic cells for attenuation of multiple sclerosis in a murine model
Localized hydrogel delivery of dendritic cells for attenuation of multiple sclerosis in a murine model Open
In multiple sclerosis (MS), abnormally activated immune cells responsive to myelin proteins result in widespread damage throughout the central nervous system (CNS) and ultimately irreversible disability. Immunomodulation by delivering dend…
View article: Machine learning algorithm for early mortality prediction in patients with advanced penile cancer
Machine learning algorithm for early mortality prediction in patients with advanced penile cancer Open
Penile cancer remains a rare cancer with an annual incidence of 1 in 100,000 men in the United States, accounting for 0.4-0.6% of all malignancies. Furthermore, to date there are no predictive models of early mortality in penile cancer. Me…