Aaron Sciore
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View article: Front Cover: Symmetry‐Directed Self‐Assembly of a Tetrahedral Protein Cage Mediated by de Novo‐Designed Coiled Coils (ChemBioChem 19/2017)
Front Cover: Symmetry‐Directed Self‐Assembly of a Tetrahedral Protein Cage Mediated by de Novo‐Designed Coiled Coils (ChemBioChem 19/2017) Open
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View article: Symmetry‐Directed Self‐Assembly of a Tetrahedral Protein Cage Mediated by de Novo‐Designed Coiled Coils
Symmetry‐Directed Self‐Assembly of a Tetrahedral Protein Cage Mediated by de Novo‐Designed Coiled Coils Open
The organization of proteins into new hierarchical forms is an important challenge in synthetic biology. However, engineering new interactions between protein subunits is technically challenging and typically requires extensive redesign of…
View article: Flexible, symmetry-directed approach to assembling protein cages
Flexible, symmetry-directed approach to assembling protein cages Open
Significance The ability to organize biological molecules into new hierarchical forms represents an important goal in synthetic biology. However, designing new quaternary interactions between protein subunits has proved technically challen…
A General, Symmetry-Based Approach for the Assembly of Proteins into Nanoscale Polyhedra. Open
The assembly of individual protein subunits into large-scale symmetrical structures is widespread in Nature and confers unique biological properties which have potential applications in nano-technology and medicine. While efforts to functi…