Aaron Webster
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View article: Novel CSF Biomarkers for facilitating diagnosis of CNS-HLH from other Neuroinflammatory Disorders
Novel CSF Biomarkers for facilitating diagnosis of CNS-HLH from other Neuroinflammatory Disorders Open
Central nervous system (CNS) hemophagocytic lymphohistiocytosis (HLH) can mimic several other neuroinflammatory disorders (ONID) often leading to misdiagnosis. Current diagnostic studies do not reliably distinguish CNS-HLH from ONID. We hy…
View article: Proteomic analysis of pericardial effusions in hematopoietic stem cell transplant recipients
Proteomic analysis of pericardial effusions in hematopoietic stem cell transplant recipients Open
Not available.
View article: Interferon-induced cell senescence as a novel mechanism of eculizumab resistance in transplant associated thrombotic microangiopathy
Interferon-induced cell senescence as a novel mechanism of eculizumab resistance in transplant associated thrombotic microangiopathy Open
Eculizumab significantly increased survival in patients with transplant associated thrombotic microangiopathy (TA-TMA), however one third of TA-TMA patients still die despite prompt treatment with eculizumab. The mechanism of eculizumab re…
View article: BIOM-88. LEPTOMENINGEAL METASTASIS IN THE INTERNAL AUDITORY CANAL AS A PREDICTOR OF OUTCOMES FOR CHILDREN WITH CENTRAL NERVOUS SYSTEM TUMORS
BIOM-88. LEPTOMENINGEAL METASTASIS IN THE INTERNAL AUDITORY CANAL AS A PREDICTOR OF OUTCOMES FOR CHILDREN WITH CENTRAL NERVOUS SYSTEM TUMORS Open
BACKGROUND Metastatic disease is a significant factor in pediatric central nervous system (CNS) tumors that affects staging, treatment approach and overall prognosis. Enhancement of the internal auditory canal (IAC) is frequently observed,…
View article: Kinetics of DNases after hematopoietic stem cell transplant
Kinetics of DNases after hematopoietic stem cell transplant Open
The entire hematopoietic system is rapidly lysed over 8 to 10 days during hematopoietic stem cell transplant (HSCT), releasing toxic intracellular molecules such as cell-free DNA (cfDNA) and proteins such as actin into the circulation. Neu…
View article: DIPG-91. CLINICAL, RADIOGRAPHIC, HISTOPATHOLOGIC, AND MOLECULAR CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA-AN UPDATE FROM THE INTERNATIONAL AND EUROPEAN SOCIETY FOR PEDIATRIC ONCOLOGY DIPG REGISTRIES (IDIPGR/SIOPE-DIPGR)
DIPG-91. CLINICAL, RADIOGRAPHIC, HISTOPATHOLOGIC, AND MOLECULAR CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA-AN UPDATE FROM THE INTERNATIONAL AND EUROPEAN SOCIETY FOR PEDIATRIC ONCOLOGY DIPG REGISTRIES (IDIPGR/SIOPE-DIPGR) Open
BACKGROUND Diffuse intrinsic pontine glioma (DIPG) is a childhood tumor with median survival of < 1 year. Survival-associated factors for this rare disease are poorly understood. METHODS Clinical, radiological, and histo-molecular data …
View article: DIPG-67. RE-IRRADIATION PRACTICES AND OUTCOMES IN PATIENTS WITH DIPG/DMG: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY
DIPG-67. RE-IRRADIATION PRACTICES AND OUTCOMES IN PATIENTS WITH DIPG/DMG: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY Open
BACKGROUND Given that radiation therapy is the only treatment modality demonstrated to result in any clinical benefit for children with DIPG, re-irradiation therapy has been explored as a treatment option for progressive DIPG. Several stud…
View article: Review of intra‐articular local anaesthetic administration in horses: Clinical indications, cytotoxicity, and outcomes
Review of intra‐articular local anaesthetic administration in horses: Clinical indications, cytotoxicity, and outcomes Open
Equine practitioners frequently inject local anaesthetics (LA) intra‐articularly in both diagnosis of lameness and for pain management intra‐ or post‐operatively with synovial endoscopy. Recent reviews of the human and veterinary literatur…
View article: Erythrocyte removal from bone marrow aspirate concentrate improves efficacy as intra-articular cellular therapy in a rodent osteoarthritis model
Erythrocyte removal from bone marrow aspirate concentrate improves efficacy as intra-articular cellular therapy in a rodent osteoarthritis model Open
These findings indicate that RBC depletion in BMAC prior to intra-articular injection improves treatment efficacy and reduces joint inflammation compared to BMAC.