Aashley S. D. Sardjoe Mishre
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View article: Cold exposure and thermoneutrality similarly reduce supraclavicular brown adipose tissue fat fraction in fasted young lean adults
Cold exposure and thermoneutrality similarly reduce supraclavicular brown adipose tissue fat fraction in fasted young lean adults Open
Brown adipose tissue (BAT) is a metabolically highly active tissue that dissipates energy stored within its intracellular triglyceride droplets as heat. Others have previously utilized MRI to show that the fat fraction of human supraclavic…
View article: Image registration and mutual thresholding enable low interimage variability across dynamic <scp>MRI</scp> measurements of supraclavicular brown adipose tissue during mild cold exposure
Image registration and mutual thresholding enable low interimage variability across dynamic <span>MRI</span> measurements of supraclavicular brown adipose tissue during mild cold exposure Open
Purpose Activated brown adipose tissue (BAT) enhances lipid catabolism and improves cardiometabolic health. Quantitative MRI of the fat fraction (FF) of supraclavicular BAT (scBAT) is a promising noninvasive measure to assess BAT activity …
View article: The Infrared Thermography Toolbox: An Open-access Semi-automated Segmentation Tool for Extracting Skin Temperatures in the Thoracic Region including Supraclavicular Brown Adipose Tissue
The Infrared Thermography Toolbox: An Open-access Semi-automated Segmentation Tool for Extracting Skin Temperatures in the Thoracic Region including Supraclavicular Brown Adipose Tissue Open
View article: Association of shivering threshold time with body composition and brown adipose tissue in young adults
Association of shivering threshold time with body composition and brown adipose tissue in young adults Open
View article: Cold-Induced Thermogenesis Shows a Diurnal Variation That Unfolds Differently in Males and Females
Cold-Induced Thermogenesis Shows a Diurnal Variation That Unfolds Differently in Males and Females Open
Context Cold exposure mobilizes lipids to feed thermogenic processes in organs, including brown adipose tissue (BAT). In rodents, BAT metabolic activity exhibits a diurnal rhythm, which is highest at the start of the wakeful period. Object…
View article: Selection Approach to Identify the Optimal Biomarker Using Quantitative Muscle MRI and Functional Assessments in Becker Muscular Dystrophy
Selection Approach to Identify the Optimal Biomarker Using Quantitative Muscle MRI and Functional Assessments in Becker Muscular Dystrophy Open
In BMD, median FF of all muscles increased over 24 months. Whole thigh 3 center slices FF reduced the sample size by approximately 40% compared to NSAA.
View article: Preserved thenar muscles in non‐ambulant Duchenne muscular dystrophy patients
Preserved thenar muscles in non‐ambulant Duchenne muscular dystrophy patients Open
Background Clinical trials in Duchenne muscular dystrophy (DMD) focus primarily on ambulant patients. Results cannot be extrapolated to later disease stages due to a decline in targeted muscle tissue. In non‐ambulant DMD patients, hand fun…
View article: The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South <scp>Asian and Europid</scp> men
The effect of mirabegron on energy expenditure and brown adipose tissue in healthy lean South <span>Asian and Europid</span> men Open
Aim To compare the effects of cold exposure and the β3‐adrenergic receptor agonist mirabegron on plasma lipids, energy expenditure and brown adipose tissue (BAT) activity in South Asians versus Europids. Materials and Methods Ten lean Dutc…
View article: Twelve weeks of exenatide treatment increases [18F]fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males
Twelve weeks of exenatide treatment increases [18F]fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males Open
Clinicaltrials.gov NCT03002675.
View article: Human Brown Adipose Tissue Estimated With Magnetic Resonance Imaging Undergoes Changes in Composition After Cold Exposure: An in vivo MRI Study in Healthy Volunteers
Human Brown Adipose Tissue Estimated With Magnetic Resonance Imaging Undergoes Changes in Composition After Cold Exposure: An in vivo MRI Study in Healthy Volunteers Open
Aim: Magnetic resonance imaging (MRI) is increasingly being used to evaluate brown adipose tissue (BAT) function. Reports on the extent and direction of cold-induced changes in MRI fat fraction and estimated BAT volume vary between …