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View article: Dried Blood Spot PCR for Detection of Congenital Cytomegalovirus Infection and Disease
Dried Blood Spot PCR for Detection of Congenital Cytomegalovirus Infection and Disease Open
This cohort study evaluates the performance of dried blood spot polymerase chain reaction (PCR) testing for the identification of congenital cytomegalovirus among infants in Minnesota.
View article: Positive Airway Pressure, Mortality, and Cardiovascular Risk in Older Adults With Sleep Apnea
Positive Airway Pressure, Mortality, and Cardiovascular Risk in Older Adults With Sleep Apnea Open
Importance Positive airway pressure (PAP) is the first-line treatment for obstructive sleep apnea (OSA), but evidence on its beneficial effect on major adverse cardiovascular events (MACE) and mortality prevention is limited. Objective To …
View article: Elevated care at home: An alternative to traditional levels of care
Elevated care at home: An alternative to traditional levels of care Open
Background Elevated care at home (ECH) is a novel in‐home care model supporting early hospital discharge and providing an alternative to institutional postacute care. Objectives This study compares patient characteristics, mortality, and r…
View article: Implementation of a structured oral hygiene program through nursing assistant education to address non‐ventilator hospital‐acquired pneumonia: A quasi‐experimental study
Implementation of a structured oral hygiene program through nursing assistant education to address non‐ventilator hospital‐acquired pneumonia: A quasi‐experimental study Open
Introduction Non‐ventilator hospital‐acquired pneumonia (NV HAP) is a common complication for hospitalized patients. NV HAP develops when patients aspirate oral secretions containing pathogenic bacteria. Appropriate oral hygiene can help m…
View article: Impact of a Pharmacist-Driven Penicillin Allergy De-Labeling Pilot Program in Preoperative Cardiothoracic and Spine Surgery Patients at a Quaternary Hospital
Impact of a Pharmacist-Driven Penicillin Allergy De-Labeling Pilot Program in Preoperative Cardiothoracic and Spine Surgery Patients at a Quaternary Hospital Open
Documented penicillin allergies are associated with an increased risk of surgical site infections (SSIs), and first-line antibiotics (e.g., cefazolin) are associated with a lower risk of SSIs. The goal of this study was to evaluate the eff…
View article: COVID-19 in pregnancy: prevalence, management, and outcomes in a single large health system
COVID-19 in pregnancy: prevalence, management, and outcomes in a single large health system Open
Pregnant patients testing positive for SARS-CoV-2 were mostly asymptomatic and identified during routine screening. Symptomatic patients were significantly more likely to require hospitalization and ICU admission with some increase in adve…
View article: Reach and effectiveness of a non-university cardio-obstetrics program
Reach and effectiveness of a non-university cardio-obstetrics program Open
Implementation of a CVOB program resulted in a more diverse patient population than previously referred to cardiology. The CVOB program participants also experienced a higher level of care in terms of increased cardiovascular testing, moni…
View article: 968. Universal Newborn Testing for Congenital Cytomegalovirus (cCMV) Infection Comes of Age: Clinical Sensitivity of Screening Tests and Infant Outcomes in a cCMV Screening Study in Minnesota
968. Universal Newborn Testing for Congenital Cytomegalovirus (cCMV) Infection Comes of Age: Clinical Sensitivity of Screening Tests and Infant Outcomes in a cCMV Screening Study in Minnesota Open
Background Universal congenital cytomegalovirus (cCMV) screening is controversial. In 2023, we completed a study evaluating analytical and clinical sensitivity of dried blood spots (DBS) for detection of cCMV infection and disease. Analyti…
View article: Prenatal and postpartum depression diagnosis in a large health system: prevalence and disparities
Prenatal and postpartum depression diagnosis in a large health system: prevalence and disparities Open
Depression symptoms and diagnoses differ by maternal characteristics during pregnancy with some groups at substantially higher risk. Efforts to examine disparities in screening and diagnosis are needed to identify reasons for variability i…
View article: The Use of Saliva Samples to Test for Congenital Cytomegalovirus Infection in Newborns: Examination of False-Positive Samples Associated with Donor Milk Use
The Use of Saliva Samples to Test for Congenital Cytomegalovirus Infection in Newborns: Examination of False-Positive Samples Associated with Donor Milk Use Open
A universal screening research study was conducted in six hospitals to identify the clinical sensitivity of polymerase chain reaction (PCR) testing on newborn dried blood spots (DBSs) versus saliva specimens for the diagnosis of congenital…
View article: A case study of an individual participant data meta-analysis of diagnostic accuracy showed that prediction regions represented heterogeneity well
A case study of an individual participant data meta-analysis of diagnostic accuracy showed that prediction regions represented heterogeneity well Open
View article: Outcomes in patients discharged with extended venous thromboembolism prophylaxis after hospitalization with COVID-19
Outcomes in patients discharged with extended venous thromboembolism prophylaxis after hospitalization with COVID-19 Open
Background: Venous thromboembolism (VTE) is a known complication of coronavirus disease (COVID-19) in patients requiring hospitalization and intensive care. We examined the association between extended pharmacological VTE prophylaxis and o…
View article: Estimated versus observed 10-year atherosclerotic cardiovascular event rates in a rural population-based health initiative: The Heart of New Ulm Project
Estimated versus observed 10-year atherosclerotic cardiovascular event rates in a rural population-based health initiative: The Heart of New Ulm Project Open
View article: Parent Weight, Diet, Active Living, and Food-Related Outcomes of the Family-Focused:NU-HOME Randomized Controlled Trial
Parent Weight, Diet, Active Living, and Food-Related Outcomes of the Family-Focused:NU-HOME Randomized Controlled Trial Open
View article: Leveraging Registered Dietitian Nutritionists and Registered Nurses in Medication Management to Reduce Therapeutic Inertia
Leveraging Registered Dietitian Nutritionists and Registered Nurses in Medication Management to Reduce Therapeutic Inertia Open
Objective To conduct a systematic review of studies that used registered dietitian nutritionists (RDNs) or registered nurses (RNs) to deliver pharmacological therapy using protocols for diabetes, dyslipidemia, or hypertension. Research Des…
View article: Implementation and Outcomes of a Model of Care for Placenta Accreta Spectrum in a Community-Based Private Practice
Implementation and Outcomes of a Model of Care for Placenta Accreta Spectrum in a Community-Based Private Practice Open
Objective The aim of the study is to describe a model of care and outcomes for placenta accreta spectrum (PAS) implemented in the context of a community based non-academic health system. Study Design The program for management of PAS inclu…
View article: Weight outcomes of NU-HOME: a randomized controlled trial to prevent obesity among rural children
Weight outcomes of NU-HOME: a randomized controlled trial to prevent obesity among rural children Open
View article: The impact of a population-based prevention program on cardiovascular events: Findings from the heart of new Ulm project
The impact of a population-based prevention program on cardiovascular events: Findings from the heart of new Ulm project Open
In HONU, the proportion of residents experiencing a CVD event was not significantly lower than a match comparison community. However, there was a significant reduction in the total number of CVD events in New Ulm, driven primarily by lower…
View article: Sensitivity of Dried Blood Spot Testing for Detection of Congenital Cytomegalovirus Infection
Sensitivity of Dried Blood Spot Testing for Detection of Congenital Cytomegalovirus Infection Open
IMPORTANCE: The sensitivity of dried blood spots (DBS) to identify newborns with congenital cytomegalovirus (cCMV) infection has not been evaluated in screening studies using the current, higher-sensitivity methods for DBS processing. OBJE…
View article: Universal childhood obesity prevention in a rural community: Study design, methods and baseline participant characteristics of the NU-HOME randomized controlled trial
Universal childhood obesity prevention in a rural community: Study design, methods and baseline participant characteristics of the NU-HOME randomized controlled trial Open
View article: Maternal and Neonatal Outcomes in Hospital-Based Deliveries With Water Immersion
Maternal and Neonatal Outcomes in Hospital-Based Deliveries With Water Immersion Open
OBJECTIVE: To compare neonatal intensive care unit (NICU) or special care nursery admission for deliveries with water immersion compared with deliveries in the matched control group without water immersion. Secondary outcomes included adve…
View article: Estimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis
Estimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis Open
Researchers increasingly use meta-analysis to synthesize the results of several studies in order to estimate a common effect. When the outcome variable is continuous, standard meta-analytic approaches assume that the primary studies report…
View article: Perinatal depression screening practices in a large health system: identifying current state and assessing opportunities to provide more equitable care
Perinatal depression screening practices in a large health system: identifying current state and assessing opportunities to provide more equitable care Open
The purpose of this study was to assess the prevalence of prenatal and postpartum depression screening in a large health system and to identify covariates for screening, with a specific focus in understanding disparities in practice. A ret…
View article: Trends in prevalence of guideline‐based use of lipid‐lowering therapy in a large health system
Trends in prevalence of guideline‐based use of lipid‐lowering therapy in a large health system Open
Background The 2013 ACC/AHA (American College of Cardiology/American Heart Association) cholesterol guidelines provided an evidence‐based rationale for the allocation of lipid‐lowering therapy based on risk for atherosclerotic cardiovascul…
View article: Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis
Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis Open
PHQ-9 ≥10 substantially overestimates depression prevalence. There is too much heterogeneity to correct statistically in individual studies.
View article: Population-Level Reach of Cardiovascular Disease Prevention Interventions in a Rural Community: Findings from the Heart of New Ulm Project
Population-Level Reach of Cardiovascular Disease Prevention Interventions in a Rural Community: Findings from the Heart of New Ulm Project Open
This study examines participation by residents of a rural community in programs implemented as part of The Heart of New Ulm (HONU) Project, a population-based cardiovascular disease (CVD) prevention initiative. The study compares participa…
View article: Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: A systematic review and individual participant data meta-analysis
Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: A systematic review and individual participant data meta-analysis Open
Item 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, most positive responses are not associated with suicidality. The…
View article: The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis
The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis Open
Background: Screening for major depression with the Patient Health Questionnaire-9 (PHQ-9) can be done using a cutoff or the PHQ-9 diagnostic algorithm. Many primary studies publish results for only one approach, and previous meta-analyses…
View article: The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis
The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis Open
Background: Screening for major depression with the Patient Health Questionnaire-9 (PHQ-9) can be done using a cutoff or the PHQ-9 diagnostic algorithm. Many primary studies publish results for only one approach, and previous…
View article: Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis – ERRATUM
Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis – ERRATUM Open
This article was published in Psychological Medicine with incorrect author information. MD Inagaki should be Masatoshi Inagaki and MD Stafford should be Lesley Stafford. This has since been updated as per the above.