Ahreum Kwon
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View article: Exploring the Relationship between Parental Stress and Child Behavioral Problems in Precocious Puberty: The Role of Parenting and Coping Strategies
Exploring the Relationship between Parental Stress and Child Behavioral Problems in Precocious Puberty: The Role of Parenting and Coping Strategies Open
Interventions should be developed and applied to help mothers of children with precocious puberty use task-focused coping strategies in stressful situations to positively impact their children's behavioral problems.
View article: Long-term tracking of glycosylated hemoglobin levels across the lifespan in type 1 diabetes: from infants to young adults
Long-term tracking of glycosylated hemoglobin levels across the lifespan in type 1 diabetes: from infants to young adults Open
Purpose: Glycosylated hemoglobin (HbA1c) is commonly used as a monitoring tool in diabetes. Due to the potential influence of insulin resistance (IR), HbA1c level may fluctuate over a person's lifetime. This study explores the long-term tr…
View article: Effectiveness and safety of pamidronate treatment in nonambulatory children with low bone mineral density
Effectiveness and safety of pamidronate treatment in nonambulatory children with low bone mineral density Open
Purpose: Nonambulatory pediatric patients may have low bone mineral density (BMD) and increased risk of pathologic fractures. Though bisphosphonate therapy is the mainstream medical intervention in these children, clinical data regarding t…
View article: Associations between Urinary Mercury/Cadmium Concentrations and Anthropometric Features in Korean Children
Associations between Urinary Mercury/Cadmium Concentrations and Anthropometric Features in Korean Children Open
Investigating the impact of urinary mercury and cadmium on anthropometric parameters in Korean children is crucial amid growing concerns about heavy metal exposure and childhood growth. Using data from the Korean National Environmental Hea…
View article: Interpretation of the <i>TRAPPC2</i> Mutation Found in a Child with Short Stature Using a Functional Study: A Case Report
Interpretation of the <i>TRAPPC2</i> Mutation Found in a Child with Short Stature Using a Functional Study: A Case Report Open
SoJin Lee, M.D., Sujin Kim, M.D., Dongju Won, M.D., Saeam Shin, M.D., Ahreum Kwon, M.D., Seung-Tae Lee, M.D., Jong Rak Choi, M.D.. Lab Med Online 2024;14:52-5. https://doi.org/10.47429/lmo.2024.14.1.52
View article: Maturity-onset diabetes of the young due to NR0B2 gene mutation
Maturity-onset diabetes of the young due to NR0B2 gene mutation Open
Highlights• This is case of a 9-year-old Korean boy with diabetes caused by a known heterozygous mutation in NR0B2.He had a positive family history of diabetes, tested negative for autoantibodies, and showed normal pancreatic function at d…
View article: Genetic and epigenetic aspects of the KISS1 and KISS1R genes in pubertal development and central precocious puberty: A review
Genetic and epigenetic aspects of the KISS1 and KISS1R genes in pubertal development and central precocious puberty: A review Open
The onset of puberty is a pivotal developmental milestone, and the release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone is a key factor in the initiation of puberty. Both kisspeptin and its receptor (KISS1) and KISS1 re…
View article: Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing
Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing Open
The intestinal mucosa is a key anatomical site for HIV-1 replication and CD4+ T cell depletion. Accordingly, in vivo treatment with an antibody to the gut-homing integrin 47 was shown to reduce viral transmission, delay disease progression…
View article: The influence of pituitary volume on the growth response in growth hormone-treated children with growth hormone deficiency or idiopathic short stature
The influence of pituitary volume on the growth response in growth hormone-treated children with growth hormone deficiency or idiopathic short stature Open
Purpose: Magnetic resonance imaging (MRI) can be used for assessing the morphology of the pituitary gland in children with short stature. The purposes of this study were: (1) to determine if pituitary volume (PV) can distinguish patients w…
View article: Parental metabolic syndrome and elevated liver transaminases are risk factors for offspring, even in children and adolescents with a normal body mass index
Parental metabolic syndrome and elevated liver transaminases are risk factors for offspring, even in children and adolescents with a normal body mass index Open
Introduction The parent–child correlation in metabolic syndrome (MetS) and elevated transaminases is sparsely researched. We assessed the correlation of parental MetS and elevated transaminase status with these conditions in their children…
View article: THU130 Long Term Tracking Of HbA1c Levels Across The Life Span In Type 1 Diabetes: From Infants To Young Adults
THU130 Long Term Tracking Of HbA1c Levels Across The Life Span In Type 1 Diabetes: From Infants To Young Adults Open
Disclosure: S. Kim: None. K. Song: None. M. Lee: None. J. Seo: None. H. Chae: None. H. Kim: None. A. Kwon: None. Objectives HbA1c is the most important monitoring value and generally used in diabetes. However, HbA1c may change across the l…
View article: THU183 The Genotype-phenotype Correlation In Human 5α-reductase Type 2 Deficiency: Classified And Analysed From A SRD5A2 Structural Perspective
THU183 The Genotype-phenotype Correlation In Human 5α-reductase Type 2 Deficiency: Classified And Analysed From A SRD5A2 Structural Perspective Open
Disclosure: A. Kwon: None. S. Kim: None. Y. Choi: None. H. Choi: None. H. Kim: None. The phenotype of 5α-Reductase type 2 deficiency (5αRD2) by SRD5A2 gene mutation varies, and even though there have been many attempts, the genotype-phenot…
View article: Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy
Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy Open
This corrects the article "Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy" on page 144.
View article: Effect of catch-up sleep on obesity in Korean adolescents: a nationwide cross-sectional study
Effect of catch-up sleep on obesity in Korean adolescents: a nationwide cross-sectional study Open
Background Adolescents have weekday/weekend sleep discrepancies and may compensate for weekday sleep debt through sleep extension on weekends. Objective We investigated the effects of total sleep duration on weekdays/weekends on obesity an…
View article: Trends in HOMA-IR values among South Korean adolescents from 2007–2010 to 2019–2020: a sex-, age-, and weight status-specific analysis
Trends in HOMA-IR values among South Korean adolescents from 2007–2010 to 2019–2020: a sex-, age-, and weight status-specific analysis Open
Background/Objectives An increase in obesity prevalence may lead to an increase in the HOMA-IR value. This study aimed to investigate changes in age- and sex-specific homeostasis model assessment of insulin resistance (HOMA-IR) values amon…
View article: Effects of Androgen Treatment on Growth in Patients with 5-α-Reductase Type 2 Deficiency
Effects of Androgen Treatment on Growth in Patients with 5-α-Reductase Type 2 Deficiency Open
Background: Patients with 5-α-reductase type 2 deficiency (5αRD2) require androgen treatment for the growth of normal male external genitalia. Since limited research has been conducted on the effects of androgen treatment on height in indi…
View article: Supplementary Figures and Legends from SPIN90 Depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression
Supplementary Figures and Legends from SPIN90 Depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression Open
Figure S1 (Related to Fig. 1). Low expression of SPIN90 in cancer stroma and CAFs. Figure S2 (Related to Fig. 2). CAFs derived from Spin90-/- mice show increased activation. Figure S3 (Related to Fig. 3). Loss of SPIN90 induces CAF differe…
View article: Data from SPIN90 Depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression
Data from SPIN90 Depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression Open
Biomechanical remodeling of stroma by cancer-associated fibroblasts (CAF) in early stages of cancer is critical for cancer progression, and mechanical cues such as extracellular matrix stiffness control cell differentiation and malignant p…
View article: Commentary on &quot;Effect of gonadotropin-releasing hormone agonist treatment on near final height in girls with central precocious puberty and early puberty&quot;
Commentary on "Effect of gonadotropin-releasing hormone agonist treatment on near final height in girls with central precocious puberty and early puberty" Open
See the article "Effect of gonadotropin-releasing hormone agonist treatment on near final height in girls with central precocious puberty and early puberty" on page 49.
View article: Supplementary Figures and Legends from SPIN90 Depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression
Supplementary Figures and Legends from SPIN90 Depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression Open
Figure S1 (Related to Fig. 1). Low expression of SPIN90 in cancer stroma and CAFs. Figure S2 (Related to Fig. 2). CAFs derived from Spin90-/- mice show increased activation. Figure S3 (Related to Fig. 3). Loss of SPIN90 induces CAF differe…
View article: The Genotype-Phenotype Correlation in Human 5α-Reductase Type 2 Deficiency: Classified and Analyzed from a SRD5A2 Structural Perspective
The Genotype-Phenotype Correlation in Human 5α-Reductase Type 2 Deficiency: Classified and Analyzed from a SRD5A2 Structural Perspective Open
The phenotype of the 5α-reductase type 2 deficiency (5αRD2) by the SRD5A2 gene mutation varies, and although there have been many attempts, the genotype-phenotype correlation still has not yet been adequately evaluated. Recently, the cryst…
View article: Neurocognitive and psychosocial profiles of children with Turner syndrome
Neurocognitive and psychosocial profiles of children with Turner syndrome Open
Purpose: Patients with Turner syndrome (TS) have distinct neurocognitive and psychosocial characteristics. However, few clinical studies have reported neuropsychological findings in Korean patients. This study investigated the neurocogniti…
View article: Comparison of the effect of gonadotropin-releasing hormone agonist dosage in girls with central precocious puberty
Comparison of the effect of gonadotropin-releasing hormone agonist dosage in girls with central precocious puberty Open
Purpose: There are no definite guidelines on the optimal dosage of gonadotropin-releasing hormone (GnRH) agonist for treatment of central precocious puberty (CPP). We compared growth outcomes of GnRH agonist at different dosages in girls w…
View article: Bone Age Estimation and Prediction of Final Adult Height Using Deep Learning
Bone Age Estimation and Prediction of Final Adult Height Using Deep Learning Open
We developed a bone age estimation program based on a deep learning algorithm. The AI-derived program demonstrated high accuracy in estimating bone age and predicting the final adult height of Korean children and adolescents.
View article: Changes in the Prevalences of Obesity, Abdominal Obesity, and Non-Alcoholic Fatty Liver Disease among Korean Children during the COVID-19 Outbreak
Changes in the Prevalences of Obesity, Abdominal Obesity, and Non-Alcoholic Fatty Liver Disease among Korean Children during the COVID-19 Outbreak Open
Our results demonstrated that the prevalences of abdominal obesity and NAFLD increased among obese Korean children and adolescents and in rural areas during the COVID-19 outbreak. Additionally, the prevalence of abdominal obesity increased…