Alam Khan
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View article: Targeting Tumorigenic Coactivators in the <scp>PI3K</scp> / <scp>AKT</scp> Signaling Pathway: A Novel Approach for Cancer Treatment
Targeting Tumorigenic Coactivators in the <span>PI3K</span> / <span>AKT</span> Signaling Pathway: A Novel Approach for Cancer Treatment Open
Objective This study aims to explore the persistent activation of the PI3K/AKT signaling pathway in various cancers, with a focus on upstream coactivators that drive tumor growth and contribute to therapeutic resistance. Methods An integra…
View article: Healing beyond medicine: Effect of nurse-led body-mind-spirit interventions on well-being in women undergoing infertility treatment
Healing beyond medicine: Effect of nurse-led body-mind-spirit interventions on well-being in women undergoing infertility treatment Open
The emotional distress and diminished hope experienced by women undergoing infertility treatment is a significant challenge. Employing a true experimental design, the study involved 100 participants selected through simple random sampling.…
View article: Empowered healing: Boosting confidence and resilience through self-affirmation in post-cesarean mothers
Empowered healing: Boosting confidence and resilience through self-affirmation in post-cesarean mothers Open
The impact of self-affirmation as a therapeutic intervention for postpartum mothers who have undergone cesarean sections, aiming to enhance their self-confidence and resilience is of interest. A true experimental design with pre-test and p…
View article: Perinatal interventions and their role in enhancing maternal-fetal attachment and mental health among first-time mothers
Perinatal interventions and their role in enhancing maternal-fetal attachment and mental health among first-time mothers Open
Maternal-fetal attachment is a crucial developmental phase, where the mother痴 emotional and psychological state can significantly impact fetal development. Therefore, it is of interest to evaluate the effectiveness of Perinatal Interventio…
View article: Harnessing the power of midwifery: Transforming self-efficacy and health navigation among women with polycystic ovarian syndrome
Harnessing the power of midwifery: Transforming self-efficacy and health navigation among women with polycystic ovarian syndrome Open
The impact of a midwife-led intervention on self-efficacy and health information-seeking behavior (HISB) in women with Polycystic Ovarian Syndrome (PCOS) is of interest. Sixty women were divided into an experimental and a control group, wi…
View article: From incision to empowerment: Enhancing maternal recovery and self-care through structured post-caesarean support
From incision to empowerment: Enhancing maternal recovery and self-care through structured post-caesarean support Open
The effect of a supportive post-operative program for improving recovery and self-care in post-caesarean mothers is of interest. The program, including pain management, wound care, nutrition support and emotional counseling, was shown to s…
View article: Exploring the Phytochemicals, Antioxidant Capacity and Cytotoxicity of Abroma augustum (L.) L.f. Seed Extract, an In vitro Study
Exploring the Phytochemicals, Antioxidant Capacity and Cytotoxicity of Abroma augustum (L.) L.f. Seed Extract, an In vitro Study Open
The antioxidant activity of Abroma augustum extract was tested via an in vitro method using zebrafish embryos in a manner similar to that used for the cytotoxicity assay. Important phytochemicals like, alkaloids, carbohydrates, flavonoids,…
View article: Exploring the Relationship Between Employees Wellbeing and Organizational Performance
Exploring the Relationship Between Employees Wellbeing and Organizational Performance Open
The research area involves exploring the dynamic connection between employee well-being (high and low), employee engagement, and organisational performance, considering the moderating effect of leadership style. It also fills a significant…
View article: DIGITAL VAGINAL EXAMINATION VS TRANSABDOMINAL ULTRASOUND ASSESSMENT TO DIAGNOSE MALPOSITION BEFORE ATTEMPTING INSTRUMENTAL VAGINAL DELIVERY – WHICH IS A BETTER TOOL
DIGITAL VAGINAL EXAMINATION VS TRANSABDOMINAL ULTRASOUND ASSESSMENT TO DIAGNOSE MALPOSITION BEFORE ATTEMPTING INSTRUMENTAL VAGINAL DELIVERY – WHICH IS A BETTER TOOL Open
Background: Fetal malposition play a vital role in the progress of labor and correct identification of the fetal position may impact the mode of delivery. The main purpose of this comparative cross-sectional study is to diagnose fetal malp…
View article: Spontaneous and pharmacologically induced hypothermia protect mice against endotoxic shock
Spontaneous and pharmacologically induced hypothermia protect mice against endotoxic shock Open
Background and Purpose Despite the well‐known occurrence of hypothermia during sepsis, its underlying biological nature and adaptive value remain debated. Experimental Approach Using indirect calorimetry, telemetry, thermal gradient studie…
View article: Comparative study of the glucose and trehalose addition on the extenders for goat sperm liquid storage.
Comparative study of the glucose and trehalose addition on the extenders for goat sperm liquid storage. Open
Objectives: The objective of this study was to assess the effects of varying glucose and trehalose concentrations on tris-citric acid-egg yolk-fructose (TCEF) diluents for the short-term cold storage of goat semen. Materials and Methods: T…
View article: An Analysis of Antibiotic Resistance in Raw Milk of Organic and Conventional Cows in District Sialkot Pakistan
An Analysis of Antibiotic Resistance in Raw Milk of Organic and Conventional Cows in District Sialkot Pakistan Open
Over the last few decades, antimicrobial resistance (AMR) has been recognized as one of the principal threats to public health. Even though the emerging crisis of AMR was formerly considered a problem to human health, it entails a “One Hea…
View article: The influence of terminal high temperature stress on membrane stability, chlorophyll content, canopy temperature and yield of wheat (Triticum aestivum L) genotypes
The influence of terminal high temperature stress on membrane stability, chlorophyll content, canopy temperature and yield of wheat (Triticum aestivum L) genotypes Open
Wheat genotypes Halna, HD2967, K911, K9006, NW 1014 and HD 2733 were grown in field condition in differential date of sowing for detection genetic variability for high temperature tolerance traits in wheat during Rabi season 2021-22. The h…
View article: Are the discoveries directed to applications? Translating the status of translational research in Peshawar, Pakistan
Are the discoveries directed to applications? Translating the status of translational research in Peshawar, Pakistan Open
Background: Translational research plays a pivotal role in transforming basic scientific discoveries into practical applications, such as drugs and treatments, to address community health needs. This study aims to assess the awareness and …
View article: Exploring the phytochemicals, antioxidancy and cytotoxicity of Abroma augustum (L.) seed extract
Exploring the phytochemicals, antioxidancy and cytotoxicity of Abroma augustum (L.) seed extract Open
Abroma augustum is an important medicinal plant that is conventionally used in the pharmaceutical industry to treat different diseases. The key objectives of this research were to assess the phytochemical, antioxidant and cytotoxic activit…
View article: The Impact of Various Organic Manures on the Germination, Development, and Growth of Okra (Abelmoschus esculentus L.)
The Impact of Various Organic Manures on the Germination, Development, and Growth of Okra (Abelmoschus esculentus L.) Open
The Department of Horticulture at Sindh Agriculture University, Tandojam conducted the pots experiment during the 2018-19 growing season to evaluate the germination, growth, and development of okra using different organic manures. The stud…
View article: Detection of heavy metals from Harpadon nehereus, Channa punctata and Pampus chinensis dried fishes and toxicity study of Channa punctata on embryonic zebrafish
Detection of heavy metals from Harpadon nehereus, Channa punctata and Pampus chinensis dried fishes and toxicity study of Channa punctata on embryonic zebrafish Open
Objectives: Globally, heavy metal pollution is one of the major serious environmental issues. The present investigations were carried out to determine the heavy metals concentrations from three dried fish along with the toxicity effects of…
View article: Aqueous plant extracts: A strategic approach to mitigate bacterial soft rot disease in onions
Aqueous plant extracts: A strategic approach to mitigate bacterial soft rot disease in onions Open
The bacterial soft rot of onion caused by Burkholderia cepacia is a major issue in subtropical storage. At BSMRAU, Bangladesh, examined plant extracts for antibacterial impact on this disease in both lab and storage contexts. Studied 11 aq…
View article: Phytochemical Analysis and Understanding the Antioxidant and Anticancer Properties of Methanol Extract from Litsea glutinosa: In Vitro and In Vivo Studies
Phytochemical Analysis and Understanding the Antioxidant and Anticancer Properties of Methanol Extract from Litsea glutinosa: In Vitro and In Vivo Studies Open
Litsea glutinosa (L. glutinosa) is considered an evidence-based medicinal plant for the treatment of cancer, the leading cause of death worldwide. In our study, the in vitro antioxidant and in vivo anticancer properties of an essential eth…
View article: Long-term effects of caesarean delivery on health and behavioural outcomes of the mother and child in Bangladesh
Long-term effects of caesarean delivery on health and behavioural outcomes of the mother and child in Bangladesh Open
Background Medically unnecessary caesarean section (CS) is now an ongoing concern worldwide including in Bangladesh. This intensifies the occurrence of adverse maternal and child health outcomes. We investigated the associations of CS with…
View article: Prevalence and Identification of Ticks in Cattle Of Rajshahi, Bangladesh
Prevalence and Identification of Ticks in Cattle Of Rajshahi, Bangladesh Open
Ticks, the notorious ectoparasite, are frequently infest cattle and cause various disease conditions and acts as vector of pathogenic organism. To determine the tick infestation in cattle of four Districts of Rajshahi Division, Bangladesh,…
View article: In Vitro Antioxidant, Cytotoxic, Thrombolytic Activities and Phytochemical Evaluation of Methanol Extract of the Ampelocissus Barbata (Wall.) Leaves
In Vitro Antioxidant, Cytotoxic, Thrombolytic Activities and Phytochemical Evaluation of Methanol Extract of the Ampelocissus Barbata (Wall.) Leaves Open
Context: Oxidative stress and pertaining counterbalance mechanism are actively working in the living organisms. The overproduction of reactive oxygen species (ROS) in the ongoing equipoising process requires to be compensated by strong ant…
View article: EVALUATION OF WATERBORNE ZINC OXIDE NANOPARTICLES INDUCED TOXICITY IN BIGHEAD CARP, HYPOPHTHALMICHTHYS NOBILIS
EVALUATION OF WATERBORNE ZINC OXIDE NANOPARTICLES INDUCED TOXICITY IN BIGHEAD CARP, HYPOPHTHALMICHTHYS NOBILIS Open
Zinc oxide nanoparticles (ZnO-NPs) have widespread applications in various industries and cosmetics that raise concerns about their hazards to the environment. Eco-toxicological data show that nanoscale zinc oxide has harmful impacts on bo…
View article: Carbofuran affects cellular autophagy and developmental senescence through the impairment of Nrf2 signalling
Carbofuran affects cellular autophagy and developmental senescence through the impairment of Nrf2 signalling Open
Carbofuran is a broad‐spectrum synthetic pesticide. Its exposure to non‐target mammals affects the biological system through the induction of oxidative stress. Since oxidative stress is a major contributing factor to cellular autophagy and…
View article: Survey on common trends for non-prescribed medication use among the young generation in Dhaka, Bangladesh: A cross sectional study
Survey on common trends for non-prescribed medication use among the young generation in Dhaka, Bangladesh: A cross sectional study Open
Background: Use of drugs without prescription is a worldwide phenomenon especially among the general people in the developing countries. Alarmingly the use of medication without prescriptions among the young generations for longer duration…
View article: IMPACT OF VAPOUR HEAT QUARANTINE TREATMENTS ON ‘SAMAR BAHISHT CHAUNSA’ AND ‘SUFAID CHAUNSA’ MANGO FRUITS DURING SIMULATED AIR SHIPMENT TO JAPAN
IMPACT OF VAPOUR HEAT QUARANTINE TREATMENTS ON ‘SAMAR BAHISHT CHAUNSA’ AND ‘SUFAID CHAUNSA’ MANGO FRUITS DURING SIMULATED AIR SHIPMENT TO JAPAN Open
Samar Bahisht Chaunsa’ and ‘Sufaid Chaunsa’ are highly admired commercial mango cultivars of Pakistan in domestic and international markets. Fruit fly being a quarantine pest has become a significant barrier in mango export trade and needs…
View article: Carbofuran accelerates the cellular senescence and declines the life span of <i>spns1</i> mutant zebrafish
Carbofuran accelerates the cellular senescence and declines the life span of <i>spns1</i> mutant zebrafish Open
Carbofuran is a carbamate pesticide, widely used in agricultural practices to increase crop productivity. In mammals, carbofuran is known to cause several untoward effects, such as apoptosis in the hippocampal neuron, oxidative stress, los…