Haidar Abdul Amir Najim Abood
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View article: Total and Specific Immunoglobulin E in Different Phenotypes of Childhood Asthma
Total and Specific Immunoglobulin E in Different Phenotypes of Childhood Asthma Open
BACKGROUND: Asthma is a heterogeneous disease with varying immunological profiles in children. Understanding differences in total and specific immunoglobulin E (IgE) levels across asthma phenotypes is critical for precise diagnosis and man…
View article: Correlation Of IL-5 And IL-17 With Specific Allergens in Pediatric Asthmatic Patients
Correlation Of IL-5 And IL-17 With Specific Allergens in Pediatric Asthmatic Patients Open
Background: This study aimed to investigate the correlation between interleukin-5 (IL-5) and interleukin-17 (IL-17) with specific aeroallergens in pediatric asthmatic patients. Patients and Methods: A cross-sectional study included (100) p…
View article: The age and residence impact on IgE serum level in patients with allergic asthma
The age and residence impact on IgE serum level in patients with allergic asthma Open
Background: Immunoglobulin E (IgE) has a role in mediating allergic reactions and their powerful effector functions, but numerous factors influence its value. Objective: To find any difference in total and specific IgE serum levels at the …
View article: Study the Association between Interleukin-4 Polymorphism and Specific Chlamydia Pneumoniae Immunoglobulin E in Asthmatic Children
Study the Association between Interleukin-4 Polymorphism and Specific Chlamydia Pneumoniae Immunoglobulin E in Asthmatic Children Open
Background: Asthma is a chronic disorder caused by complex interactions between genetic and environmental influences. Objective: Investigate the possible correlation between interleukin-4 (IL-4) gene polymorphisms and development of specif…
View article: Association of Interleukin-4 in Immunoglobulin-E Mediated Asthma: A Cross Sectional Study
Association of Interleukin-4 in Immunoglobulin-E Mediated Asthma: A Cross Sectional Study Open
Backgrounds: Interleukin 4 (IL 4) is a cytokine associated with the cause of several allergic diseases such as asthma due to their function in the differentiation of T helper type 2 lymphocytes and induction of the IgE isotype switch. Obje…
View article: Positive Associations of Chlamydia pneumoniae Immunoglobulin G and Immunoglobulin E Antibodies and Asthma in Iraqi Children
Positive Associations of Chlamydia pneumoniae Immunoglobulin G and Immunoglobulin E Antibodies and Asthma in Iraqi Children Open
BACKGROUND: Chlamydia pneumoniae is an intracellular bacterium that causes respiratory tract infection. AIM AND OBJECTIVE: The objective of the study was to evaluate the association between past C. pneumoniae infection and asthma. MATERIAL…
View article: Interleukin-5 and Interleukin-5 Receptor Polymorphism in Asthma
Interleukin-5 and Interleukin-5 Receptor Polymorphism in Asthma Open
Asthma is a common chronic inflammatory disease of the airways of the lungs, in the world. It’s associated with type 2 cytokines interleukin-4, IL-5, and IL-13, which promote airway eosinophilia, bronchial hyperresponsiveness, mucus overpr…
View article: Elevated serum levels of interleukin -22 and interleukin-23 in pediatric asthma
Elevated serum levels of interleukin -22 and interleukin-23 in pediatric asthma Open
Background: There are few studies had addressed the association between serum levels of Interleukin -22 and Interleukin-23 with severity of asthma, this study aims to evaluate whether elevated IL-22 and IL-23 serum levels is related to the…
View article: The Association Between Vitamin D Deficiency and Childhood Asthma
The Association Between Vitamin D Deficiency and Childhood Asthma Open
BACKGROUND: Asthma, a major public health issue, is one of the most common diseases affecting millions of population globally. It is a chronic respiratory disease characterized by increased airway inflammation and hyper-responsiveness. Vit…
View article: Impact of 27Gln\Glu Polymorphisms of β2-Adrenergic Receptor Gene on Pulmonary Function in Asthmatic Children Treated with Nebulized Salbutamol
Impact of 27Gln\Glu Polymorphisms of β2-Adrenergic Receptor Gene on Pulmonary Function in Asthmatic Children Treated with Nebulized Salbutamol Open
Background: The β 2 -adrenergic receptor gene is a typical candidate for the study of genetic polymorphism. Many patients with asthma do not respond to β2-agonist; in addition, a wide interindividual variability in pharmacological response…
View article: The Effect of 16 Arg/Gly β2–Adrenergic Receptors Gene Polymorphism on Pulmonary Function in Asthmatic Children Treated with Nebulized Salbutamol
The Effect of 16 Arg/Gly β2–Adrenergic Receptors Gene Polymorphism on Pulmonary Function in Asthmatic Children Treated with Nebulized Salbutamol Open
Background: The β 2 -adrenergic receptor gene is a typical candidate for the study of genetic polymorphism, the biological relevance, and clinical consequences of polymorphisms. Many patients with asthma do not respond to β2-agonist; in ad…
View article: Letter from Iraq
Letter from Iraq Open
Asthma is the most common chronic childhood illness with many hospital visits and school absences. Many parents do not allow their children with asthma to engage in sports with their peers, often leading to great psychological impact on th…
View article: Effects of montelukast versus inhaled beclomethasone on asthma control and immunoglobulin-E levels in asthmatic children
Effects of montelukast versus inhaled beclomethasone on asthma control and immunoglobulin-E levels in asthmatic children Open
Background: Beclomethasone dipropionate inhaler is a corticosteroid medication used as the controller of persistent asthma. Montelukast is a leukotriene receptor antagonist used as the second-line in controlling the symptoms of the asthmat…
View article: Association between the interleukin-5 receptor alpha-subunit G-80A polymorphism and immunological parameters in asthmatic children
Association between the interleukin-5 receptor alpha-subunit G-80A polymorphism and immunological parameters in asthmatic children Open
Introduction: The expression of human interleukin-5 (IL-5) receptor alpha (Rα)-subunit presented on eosinophils, mast cells, and basophils. Hence, a polymorphism in IL-5 Rα may be implicated in the development of asthma and effect on immun…
View article: Systematic review and meta-analysis of the association between C-746T and C-703T polymorphisms of the interleukin-5 gene and asthma
Systematic review and meta-analysis of the association between C-746T and C-703T polymorphisms of the interleukin-5 gene and asthma Open
Background: Asthma is a common disease with a complex risk architecture including both genetic and environmental factors. A number of studies have identified the association between interleukin (IL)-5 C-746T and C-703T polymorphisms and as…
View article: The correlation between total immunoglobulin-E levels and interleukin-13 gene polymorphism in asthmatic children treated with inhaled corticosteroids or montelukast
The correlation between total immunoglobulin-E levels and interleukin-13 gene polymorphism in asthmatic children treated with inhaled corticosteroids or montelukast Open
Background: The aim of this research was to study the possible correlation between single-nucleotide polymorphism of interleukin (IL)-13-1112 C/T with specific parameters in asthmatic children (total serum immunoglobulin-E [TSIgE] levels a…
View article: To evaluate total serum immunoglobulin E level and factors that effect on this level in Iraqi asthmatic children
To evaluate total serum immunoglobulin E level and factors that effect on this level in Iraqi asthmatic children Open
Background: Immunoglobulin E (IgE) has an important role in allergic disease, especially in asthma because it is highly responsive to the allergens; hence, the measure of IgE levels helps in the diagnosis of asthma and monitoring the patie…
View article: Study of serum interleukin 5 level and factors that impact on this level in Iraqi asthmatic children
Study of serum interleukin 5 level and factors that impact on this level in Iraqi asthmatic children Open
Background: Interleukin-5 (IL-5) is a cytokine associated with the cause of several allergic diseases such as asthma due to their function in growth, activation, and maturation of eosinophils and stimulates B-cell growth and increases immu…
View article: Specific IL-5 snp is associated with high serum IL-5 levels and higher eosinophil counts among iraqi asthmatic children
Specific IL-5 snp is associated with high serum IL-5 levels and higher eosinophil counts among iraqi asthmatic children Open
Objective: Interleukin-5 (IL-5) is a cytokine known to play major role in the regulation of eosinophil formation, maturation, recruitment, and survival. Hence, an increased production of IL-5 may be contributed to the pathogenesis of eosin…
View article: Study of the correlation between total immunoglobulin-E levels and Inter-leukin-4 polymorphism in asthmatic children
Study of the correlation between total immunoglobulin-E levels and Inter-leukin-4 polymorphism in asthmatic children Open
The aim of this study is to analyze the possible correlation between the single nucleotide polymorphisms (SNP) IL-4-590C/T with specific parameters in asthmatic children (blood eosinophils, total serum immunoglobulin-E (TSIgE) levels, and …
View article: TECHNICAL ERRORS IN USING INHALERS AMONG PATIENTS WITH ASTHMA OR COPD IN IRAQ
TECHNICAL ERRORS IN USING INHALERS AMONG PATIENTS WITH ASTHMA OR COPD IN IRAQ Open
Background Inhaler is a device holding a medicine taking by breathing (inhalation).It is estimated that about 25 billion dollars spent for inhalers annually, 5-7 billion dollars are wasted because of inhaler misuse. ObjectiveTo evaluate in…