Abdullah AI Emran
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View article: YAP1 drives aggressive and therapy resistant state in melanoma through reprogramming the chromatin and regulating immune evasive programs
YAP1 drives aggressive and therapy resistant state in melanoma through reprogramming the chromatin and regulating immune evasive programs Open
Despite promising initial results in targeting the RAF-MEK-ERK cascade, resistance to BRAF/MEK inhibitors remains a critical challenge in nearly 50% of melanoma patients. Our study demonstrates that robust YAP1 activation in metastatic mel…
View article: 1244 Epigenetic & metabolic vulnerabilities of adaptive drug resistance to targeted therapies in melanoma
1244 Epigenetic & metabolic vulnerabilities of adaptive drug resistance to targeted therapies in melanoma Open