Abdullah Akhtar Ahmed
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View article: Correction: Multi-step organic synthesis, cytotoxicity, and molecular docking of new N-phenylpyrazolones incorporated with N-benzylthiazole or N-benzyl-4-thiazolone fragments
Correction: Multi-step organic synthesis, cytotoxicity, and molecular docking of new N-phenylpyrazolones incorporated with N-benzylthiazole or N-benzyl-4-thiazolone fragments Open
View article: Multi-step organic synthesis, cytotoxicity, and molecular docking of new N-phenylpyrazolones incorporated with N-benzylthiazole or N-benzyl-4-thiazolone fragments
Multi-step organic synthesis, cytotoxicity, and molecular docking of new N-phenylpyrazolones incorporated with N-benzylthiazole or N-benzyl-4-thiazolone fragments Open
Building on our previous research on edaravone-derived bioactive small molecules, the precursors 2-5 were synthesized by condensation reactions between 4-{[(4-acetylphenyl)amino]methylidene}-5-methyl-2-phenylpyrazol-3-one (1) and a variety…
View article: Feeding Behavior and Host Plant Preferences of Episyrphus balteatus (DeGeer) and Ischiodon scutellaris (Fabricius) in Southern Punjab, Pakistan
Feeding Behavior and Host Plant Preferences of Episyrphus balteatus (DeGeer) and Ischiodon scutellaris (Fabricius) in Southern Punjab, Pakistan Open
During the present study, 300 adults along with 30 larvae of Episyrphus balteatus and 212 adults along with 25 larvae of Ischiodon scutellaris were collected from 15 and 13 host plants, respectively from Bahawalpur, Southern Punjab, Pakist…
View article: Investigating the Anti-inflammatory Effect of Quinoline Derivative: N1-(5-methyl-5H-indolo[2,3-b]quinolin-11-yl)benzene-1,4-diamine Hydrochloride Loaded Soluble Starch Nanoparticles Against Methotrexate-induced Inflammation in Experimental Model
Investigating the Anti-inflammatory Effect of Quinoline Derivative: N1-(5-methyl-5H-indolo[2,3-b]quinolin-11-yl)benzene-1,4-diamine Hydrochloride Loaded Soluble Starch Nanoparticles Against Methotrexate-induced Inflammation in Experimental Model Open
Background It is necessary to develop advanced therapies utilizing natural ingredients with anti-inflammatory qualities in order to lessen the negative effects of chemotherapeutics. Results The bioactive N1-(5-methyl-5H-indolo[2,3-b]quinol…
View article: Nano-Magnetic Sugarcane Bagasse Cellulosic Composite as a Sustainable Photocatalyst for Textile Industrial Effluent Remediation
Nano-Magnetic Sugarcane Bagasse Cellulosic Composite as a Sustainable Photocatalyst for Textile Industrial Effluent Remediation Open
Researchers have focused on deriving environmentally benign materials from biomass waste and converting them into value-added materials. In this study, cellulosic crystals derived from sugarcane bagasse (SCB) are augmented with magnetite (…
View article: Nd(III) sorption using aminophosphonate-based sorbents – Sorption properties and application to the treatment of REE concentrate
Nd(III) sorption using aminophosphonate-based sorbents – Sorption properties and application to the treatment of REE concentrate Open
View article: Growth inhibition of Salmonella by Leuconostoc species isolated from buffalo milk curd
Growth inhibition of Salmonella by Leuconostoc species isolated from buffalo milk curd Open
Traditional fermented products are considered to be a niche for microbial diversity. Probiotics offer a unique approach for addressing the threat of antibiotic resistance. Therefore, the aim of the present study was to isolate Leuconostoc …
View article: Dengue Vaccine: Challenges and Limitations
Dengue Vaccine: Challenges and Limitations Open
Dengue is a common mosquito-transmitted viral infectious disease. Due to global warming and other climate changes, the dengue virus vector Aedes aegypti mosquito is breeding rapidly and spreading the dengue worldwide. As a result, every ye…
View article: Unveiling the Stealthy Threat: Analyzing Slow Drift GPS Spoofing Attacks for Autonomous Vehicles in Urban Environments and Enabling the Resilience
Unveiling the Stealthy Threat: Analyzing Slow Drift GPS Spoofing Attacks for Autonomous Vehicles in Urban Environments and Enabling the Resilience Open
Autonomous vehicles (AVs) rely on the Global Positioning System (GPS) or Global Navigation Satellite Systems (GNSS) for precise (Positioning, Navigation, and Timing) PNT solutions. However, the vulnerability of GPS signals to intentional a…
View article: Cytotoxic Potential of Novel Quinoline Derivative: 11-(1,4-Bisaminopropylpiperazinyl)5-methyl-5H-indolo[2,3-b]quinoline against Different Cancer Cell Lines via Activation and Deactivation of the Expression of Some Proteins
Cytotoxic Potential of Novel Quinoline Derivative: 11-(1,4-Bisaminopropylpiperazinyl)5-methyl-5H-indolo[2,3-b]quinoline against Different Cancer Cell Lines via Activation and Deactivation of the Expression of Some Proteins Open
The current study evaluated the cytotoxic activity of 11-(1,4-bisaminopropylpiperazinyl)5-methyl-5H-indolo[2,3-b]quinoline (BAPPN), a novel derivative of 5-methyl-5H-indolo[2,3-b]quinoline, against hepatocellular carcinoma (HepG2), colon c…
View article: Biochemical properties and antimicrobial susceptibility pattern of Rothia mucilaginosa isolated from patients with respiratory tract infections
Biochemical properties and antimicrobial susceptibility pattern of Rothia mucilaginosa isolated from patients with respiratory tract infections Open
Background: Rothia mucilaginosa is appearing as an alarming pathogen for respiratory tract infection, infection of prosthetic devices and endocarditis. Over the past few years, Rothia sp. are frequently identified in a tertiary hospital of…
View article: Vibrio fluvialis: An Emerging Pathogen for Intestinal and Extraintestinal Infections
Vibrio fluvialis: An Emerging Pathogen for Intestinal and Extraintestinal Infections Open
The genus Vibrio is a ubiquitous group of bacteria belonging in the family Vibrionaceae. More than 100 species have been discovered in the genus Vibrio and about 14 of them have been reported to cause several human infections. Vibrio fluvi…
View article: Molluscicidal and Larvicidal Potency of N-Heterocylic Analogs against Biomophalaria alexandrina Snails and Schistosoma mansoni Larval Stages
Molluscicidal and Larvicidal Potency of N-Heterocylic Analogs against Biomophalaria alexandrina Snails and Schistosoma mansoni Larval Stages Open
This work describes the synthesis of quinoline-based N--heterocyclic arenes and their biological evaluation as molluscicides against adult Biomophalaria alexandrina snails as well as larvicides against Schistosoma mansoni larvae (miracidia…
View article: Impact of Synthesized Indoloquinoline Analog to Isolates from Cryptolepis sanguinolenta on Tumor Growth Inhibition and Hepatotoxicity in Ehrlich Solid Tumor-Bearing Female Mice
Impact of Synthesized Indoloquinoline Analog to Isolates from Cryptolepis sanguinolenta on Tumor Growth Inhibition and Hepatotoxicity in Ehrlich Solid Tumor-Bearing Female Mice Open
The study evaluated the antitumor efficacy of APAN, “synthesized indoloquinoline analog derived from the parent neocryptolepine isolated from the roots of Cryptolepis sanguinolenta”, versus the chemotherapeutic drug etoposide (ETO) in Ehrl…
View article: A Rare Case of Burkholderia Cepacia Complex Septicemia in a Newborn
A Rare Case of Burkholderia Cepacia Complex Septicemia in a Newborn Open
Burkholderia cepacia complex (Bcc) has rarely been reported to cause sepsis in newborns. A case in a newborn male was reported in a tertiary hospital in northern part of Bangladesh Khwaja Yunus Ali Medical College and Hospital, Sirajganj. …
View article: Synthesis, Biocidal and Antibiofilm Activities of New Isatin–Quinoline Conjugates against Multidrug-Resistant Bacterial Pathogens along with Their In Silico Screening
Synthesis, Biocidal and Antibiofilm Activities of New Isatin–Quinoline Conjugates against Multidrug-Resistant Bacterial Pathogens along with Their In Silico Screening Open
Isatin–quinoline conjugates 10a–f and 11a–f were assembled by the reaction of N-(bromobutyl) isatin derivatives 3a, b with aminoquinolines 6a–c and their corresponding hydrazinyl 9a–c in good yields. The structures of the resulting conjuga…
View article: The histologic effects of high doses of botulinum toxin a on the rabbit's salivary gland
The histologic effects of high doses of botulinum toxin a on the rabbit's salivary gland Open
The exact mechanism of botulinum toxin A (BTX-A) on submandibular salivary gland (SMG) regarding its function and histology remains unclear. The goal of this work is to clarify the histological effects of BTX-A (at high doses) in SMG in ra…
View article: Expression of Ki67 in submandibular salivary glands of rabbits after BTX injection: Histological and immunohistochemical study
Expression of Ki67 in submandibular salivary glands of rabbits after BTX injection: Histological and immunohistochemical study Open
This study aimed to examine the possible histological effects of local injections of BTX in rabbits submandibular SGs and to find the dose-dependent and time relationship between injections and study immunohistochemistry expression of Ki67…
View article: Synthesis, Nanoformulations, and In Vitro Anticancer Activity of N-Substituted Side Chain Neocryptolepine Scaffolds
Synthesis, Nanoformulations, and In Vitro Anticancer Activity of N-Substituted Side Chain Neocryptolepine Scaffolds Open
The naturally occurring neocryptolepine (5-Methylindolo [2,3-b]quinoline) and its analogs exhibited prominent anticancer and antimalarial activity. However, the main problem of this class of compounds is their poor aqueous solubility, hamp…
View article: Experimental and Molecular Docking Studies of Cyclic Diphenyl Phosphonates as DNA Gyrase Inhibitors for Fluoroquinolone-Resistant Pathogens
Experimental and Molecular Docking Studies of Cyclic Diphenyl Phosphonates as DNA Gyrase Inhibitors for Fluoroquinolone-Resistant Pathogens Open
DNA gyrase and topoisomerase IV are proven to be validated targets in the design of novel antibacterial drugs. In this study, we report the antibacterial evaluation and molecular docking studies of previously synthesized two series of cycl…
View article: Bacteriological profile and antimicrobial susceptibility patterns of symptomatic bloodstream infection in Dhaka City
Bacteriological profile and antimicrobial susceptibility patterns of symptomatic bloodstream infection in Dhaka City Open
INTRODUCTION: Bacteremia, is regarded as a significant reason in all over the world for morbidity and mortality in mainly sick patients. Invasion by microorganisms in blood constitutes the critical issues in infectious disease. The aims an…
View article: Call to Start Antimicrobial Stewardship Program
Call to Start Antimicrobial Stewardship Program Open
not available
KYAMC Journal.2021;12(01): 01-02
View article: Emergence of Colistin Resistant Gram-Negative Bacteria in a Tertiary Care Rural Hospital in 2019
Emergence of Colistin Resistant Gram-Negative Bacteria in a Tertiary Care Rural Hospital in 2019 Open
Background: Colistin-resistant Gram-negative bacteria is a rapidly emerging global threatgenerated a sense of public alarm.
Objective: To combat this challenge a study was designedto evaluate the fast spreading infections by colistin-resi…
View article: PRP in recurrent implantation failure, hope or hype? A Prospective randomized controlled study
PRP in recurrent implantation failure, hope or hype? A Prospective randomized controlled study Open
Introduction: The endometrial function and endometrial receptivity have been accepted to be major limiting factors in the establishment of pregnancy. In spite of improved almost all aspects of IVF: ovarian stimulation, embryo culture and t…
View article: Detection of Metallo β- Lactamase producing Pseudomonas aeruginosa isolated from patients in Saudi Arabia
Detection of Metallo β- Lactamase producing Pseudomonas aeruginosa isolated from patients in Saudi Arabia Open
View article: Know and Care Life Friends -Microbiota
Know and Care Life Friends -Microbiota Open
not available KYAMC Journal Vol. 9, No.-3, October 2018, Page 101-103
View article: FURTHER STUDIES ON MULBERRY SILK WORM, BOMBYX MORI L.
FURTHER STUDIES ON MULBERRY SILK WORM, BOMBYX MORI L. Open
View article: Trends in antibiotic resistance patterns of methicillin resistant and methicillin sensitive Staphylococcus aureus in Khwaja Yunus Ali Medical College Hospital
Trends in antibiotic resistance patterns of methicillin resistant and methicillin sensitive Staphylococcus aureus in Khwaja Yunus Ali Medical College Hospital Open
Background: Antimicrobial resistance in pathogens is a growing concern for health. It is a great concern around the globe about the threat of increasing antimicrobial resistance. In response to this concerns, medical experts have proposed …
View article: Web Assessment of Libyan Government e-Government Services
Web Assessment of Libyan Government e-Government Services Open
Libya has started transferring traditional govern-ment services into e-government services. The e-government initiative involves the use of websites to offer various services such as civil registration, financial transaction and private in…