Ahmed Z. Alanazi
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View article: Sex-stratified analysis of complete blood count parameters in Helicobacter pylori infection: A retrospective cohort study revealing distinct hematological mechanisms
Sex-stratified analysis of complete blood count parameters in Helicobacter pylori infection: A retrospective cohort study revealing distinct hematological mechanisms Open
Background Helicobacter pylori infection affects approximately 50% of the global population and is associated with hematological manifestations. Despite established associations with anemia, sex-specific effects remain unexplored, limiting…
View article: Prevalence and experiences of sexual harassment among Saudi female nursing students: a cross-sectional study
Prevalence and experiences of sexual harassment among Saudi female nursing students: a cross-sectional study Open
More than half of nursing students reported experiencing sexual harassment during clinical training, highlighting a serious concern. Academic institutions and health policymakers must ensure a safe clinical environment through awareness se…
View article: Comprehensive Care Approaches in Psychiatric Nursing: Evidence-Based Strategies for Optimal Patient Outcomes
Comprehensive Care Approaches in Psychiatric Nursing: Evidence-Based Strategies for Optimal Patient Outcomes Open
Psychiatric patient care demands specialized nursing approaches that integrate biological, psychological, and social dimensions of mental health within evidence-based frameworks. This comprehensive literature review examined peer-reviewed …
View article: Comparative safety and efficacy of Rituximab biosimilar (Truxima) and the reference rituximab product (MabThera) in the treatment of different types of adult glomerulonephritis
Comparative safety and efficacy of Rituximab biosimilar (Truxima) and the reference rituximab product (MabThera) in the treatment of different types of adult glomerulonephritis Open
Background: The most important advancement in the treatment of glomerulonephritis is the application of rituximab (MabThera®), for several decades. Rituximab biosimilar (Truxima®) was approved for the same indications offering significant …
View article: Investigation of The Hepatoprotective Potential of Liposomal Resveratrol as Polyphenols Against Liver Damage in Streptozotocin Diabetic Rat Model
Investigation of The Hepatoprotective Potential of Liposomal Resveratrol as Polyphenols Against Liver Damage in Streptozotocin Diabetic Rat Model Open
Diabetes Mellitus is a prominent contributor to degenerative diseases globally and is often associated with hepatic injury. The dysfunction of the liver is characterized by cirrhosis, inflammation, apoptosis, and impaired antioxidant defen…
View article: Subtractive proteomics and molecular docking identify therapeutic targets and drug candidates in drug resistant Klebsiella Michiganensis THO-011
Subtractive proteomics and molecular docking identify therapeutic targets and drug candidates in drug resistant Klebsiella Michiganensis THO-011 Open
Klebsiella michiganensis, an emerging multidrug-resistant pathogen, poses a significant public health threat. This study employed subtractive genomics to identify potential therapeutic targets in K. michiganensis THO-011. From 4,024 predic…
View article: Efficacy and Safety of Adenotonsillectomy for Pediatric Obstructive Sleep Apnea Across Various Age Groups: A Systematic Review
Efficacy and Safety of Adenotonsillectomy for Pediatric Obstructive Sleep Apnea Across Various Age Groups: A Systematic Review Open
Objectives: To assess the safety and efficacy of adenotonsillectomy (AT) for treating uncomplicated pediatric obstructive sleep apnea (OSA) in children of different ages. Methods: A systematic search was conducted in four electronic databa…
View article: A comparative analysis of student perceptions on the effectiveness of academic advising at king saud university: a focus on experiences, satisfaction, and outcomes
A comparative analysis of student perceptions on the effectiveness of academic advising at king saud university: a focus on experiences, satisfaction, and outcomes Open
The current study investigated how students at King Saud University's College of Pharmacy perceive the effectiveness of the Academic Advising Unit and their experiences with academic advisors. Our study examined responses gathered from 164…
View article: Diabetes Self-Care of People with Type 2 Diabetes Mellitus among Outpatients in Riyadh Hospitals: A Cross-Sectional Study
Diabetes Self-Care of People with Type 2 Diabetes Mellitus among Outpatients in Riyadh Hospitals: A Cross-Sectional Study Open
Background The purpose of this research was to explore the self-care behaviors of Type 2 Diabetes Mellitus (DMT2) patients visiting outpatient departments in Riyadh hospitals and to analyze the correlation between demographic profiles and …
View article: Modulation of Chemotherapy Sensitivity of Breast Cancer Cells through Transforming Growth Factor-beta Pathway-mediated Alterations in DNA Damage Response
Modulation of Chemotherapy Sensitivity of Breast Cancer Cells through Transforming Growth Factor-beta Pathway-mediated Alterations in DNA Damage Response Open
Chemotherapeutic drugs, like cisplatin, function by damaging genomic DNA, thus inducing cell apoptosis. Cancer cells can enhance their DNA repair capacity, leading to chemotherapeutic resistance. Nucleotide excision repair (NER) involves r…
View article: Risk assessment and management strategies for peri-implantitis in high-risk populations
Risk assessment and management strategies for peri-implantitis in high-risk populations Open
Peri-implantitis is a multifactorial condition characterized by inflammation and progressive bone loss surrounding dental implants, often leading to implant failure. High-risk populations, including patients with systemic conditions such a…
View article: Dual-emission ratiometric fluorescent sensor based on tannic acid carbon dots and eosin for selective detection of paraquat in water and food samples
Dual-emission ratiometric fluorescent sensor based on tannic acid carbon dots and eosin for selective detection of paraquat in water and food samples Open
Detection mechanism of paraquat.
View article: Repurposing disposable medical syringes into valuable fluorescent carbon dots: application to the fluorometric determination of nintedanib
Repurposing disposable medical syringes into valuable fluorescent carbon dots: application to the fluorometric determination of nintedanib Open
Monitoring nintedanib (NTB) using reliable analytical methods is essential for ensuring safe dosing, minimizing toxicity, assessing drug–drug interactions, and supporting quality control in personalized cancer therapy.
View article: Diabetic retinopathy: knowledge, attitudes, and practices among diabetic patients
Diabetic retinopathy: knowledge, attitudes, and practices among diabetic patients Open
View article: Zirconia Crowns as an Advanced Solution for Pediatric Dental Caries: A Comprehensive Review of Biochemical Considerations and Management Approaches
Zirconia Crowns as an Advanced Solution for Pediatric Dental Caries: A Comprehensive Review of Biochemical Considerations and Management Approaches Open
Background: Pediatric dental caries is a prevalent issue, necessitating effective restorative solutions. Zirconia crowns have emerged as a promising option due to their superior mechanical properties and aesthetics compared to traditional …
View article: Exploring Awareness Levels of Diabetic Ketoacidosis Risk Among Patients with Diabetes: A Cross-Sectional Study
Exploring Awareness Levels of Diabetic Ketoacidosis Risk Among Patients with Diabetes: A Cross-Sectional Study Open
Background/Objectives: Diabetic ketoacidosis (DKA) is a critical complication of diabetes mellitus, posing significant health. While global studies have indicated a concerning lack of awareness regarding DKA among patients with diabetes, r…
View article: Naringenin Mitigates Dasatinib-Induced Kidney Damage by Modulating Antioxidant Defense, Inflammation, and Apoptosis Pathways
Naringenin Mitigates Dasatinib-Induced Kidney Damage by Modulating Antioxidant Defense, Inflammation, and Apoptosis Pathways Open
Nephrotoxicity remains a significant concern associated with tyrosine kinase inhibitors, such as dasatinib (DASA). Previous studies have shown that DASA can induce renal tubular cell death, contributing to its nephrotoxic effects. In contr…
View article: Integrating Metabolomics, Histopathology, and Cardiac Marker Analysis to Assess Valsartan’s Efficacy in Mitigating Dasatinib-Induced Cardiac Toxicity in Sprague-Dawley Rats
Integrating Metabolomics, Histopathology, and Cardiac Marker Analysis to Assess Valsartan’s Efficacy in Mitigating Dasatinib-Induced Cardiac Toxicity in Sprague-Dawley Rats Open
The study suggesting VAL's potential therapeutic role in managing DASA-induced cardiac toxicity. The combination of VAL with DASA not only improved survival rates and reduced cardiac biomarker levels but also preserved myocardial architect…
View article: Cardioprotective effects of liposomal resveratrol in diabetic rats: unveiling antioxidant and anti-inflammatory benefits
Cardioprotective effects of liposomal resveratrol in diabetic rats: unveiling antioxidant and anti-inflammatory benefits Open
As a consequence of chronic hyperglycemia, diabetes complications and tissue damage are exacerbated. There is evidence that natural phytochemicals, including resveratrol, a bioactive polyphenol, may be able to reduce oxidative stress and i…
View article: Impact of Hyperuricemia on Clinical Outcomes in Sepsis Patients: A Retrospective Cohort Study
Impact of Hyperuricemia on Clinical Outcomes in Sepsis Patients: A Retrospective Cohort Study Open
Background: Hyperuricemia has been linked to various adverse clinical outcomes. Data on the clinical outcomes and the relationship between hyperuricemia and sepsis remain limited. The aim of this study was to evaluate the impact of hyperur…
View article: Closing the loop: Strengthening course quality of Pharm.D. program via applying a comprehensive four-step review approach
Closing the loop: Strengthening course quality of Pharm.D. program via applying a comprehensive four-step review approach Open
This study explores the course review process implemented by the College of Pharmacy at King Saud University for its Pharm.D. program. Through a qualitative research design, a dedicated course review committee was established to oversee th…
View article: Collaboration Between Nursing, Health Assistance, and Emergency Medical Services During Cardiac Arrest Management
Collaboration Between Nursing, Health Assistance, and Emergency Medical Services During Cardiac Arrest Management Open
Collaboration among nursing staff, health assistance personnel, and emergency medical services (EMS) is crucial in the effective management of cardiac arrest situations. When a cardiac arrest occurs, the immediate response from all healthc…
View article: Genetic variants associated with dengue hemorrhagic fever. A systematic review and meta-analysis
Genetic variants associated with dengue hemorrhagic fever. A systematic review and meta-analysis Open
Dengue hemorrhagic fever (DHF) is a severe condition resulting from the dengue virus, with four serotypes known as DEN-1, DEN-2, DEN-3, and DEN-4. Genetic variations play a crucial role in influencing susceptibility to DHF. Therefore, this…
View article: Advancements in pre-hospital emergency care: Challenges and innovations
Advancements in pre-hospital emergency care: Challenges and innovations Open
Background: The development of newer communication and monitoring technologies using mobile devices in pre-hospital aspects of care is changing the focus and practice of emergency medical services (EMS). Aim: This study focuses on the role…
View article: The effect of inhibiting hindbrain A2 noradrenergic neurons by 6-Hydroxydopamine on lipopolysaccharide-treated male rats autistic animal model
The effect of inhibiting hindbrain A2 noradrenergic neurons by 6-Hydroxydopamine on lipopolysaccharide-treated male rats autistic animal model Open
View article: Cobalt-modulated dual emission carbon dots for ratiometric fluorescent vancomycin detection
Cobalt-modulated dual emission carbon dots for ratiometric fluorescent vancomycin detection Open
Selective fluorometric protocol for the quantification of vancomycin.
View article: Sol–gel derived ceramic nanocomposite CNFs anchored with a nanostructured CeO <sub>2</sub> modified graphite electrode for monitoring the interaction of a selective tyrosine kinase inhibitor capmatinib with dsDNA
Sol–gel derived ceramic nanocomposite CNFs anchored with a nanostructured CeO <sub>2</sub> modified graphite electrode for monitoring the interaction of a selective tyrosine kinase inhibitor capmatinib with dsDNA Open
In the current study, the potential interaction mechanisms between capmatinib (CAP), a selective tyrosine kinase inhibitor, and calf thymus double-stranded DNA (ds-DNA) were evaluated.
View article: Selective fluorescence turn-on detection of combination cisplatin–etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe
Selective fluorescence turn-on detection of combination cisplatin–etoposide chemotherapy based on N-CDs/GSH-CuNCs nanoprobe Open
Cisplatin (CIS) and etoposide (ETP) simultaneous determination using N-CDs/GSH-CuNCs nanoprobe.
View article: Examining the Effects of Dasatinib, Sorafenib, and Nilotinib on Vascular Smooth Muscle Cells: Insights into Proliferation, Migration, and Gene Expression Dynamics
Examining the Effects of Dasatinib, Sorafenib, and Nilotinib on Vascular Smooth Muscle Cells: Insights into Proliferation, Migration, and Gene Expression Dynamics Open
Background: Dasatinib, nilotinib, and sorafenib are clinically proven tyrosine kinase inhibitors (TKIs) used for the treatment of leukemia and hepatocellular carcinoma. However, there is a growing concern regarding cardiotoxicity associate…
View article: Augmented antitumor effects of erlotinib and cabozantinib on A549 non-small cell lung cancer: In vitro and in vivo studies
Augmented antitumor effects of erlotinib and cabozantinib on A549 non-small cell lung cancer: In vitro and in vivo studies Open