Abdurrahman El-Fulaty Ahmad
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View article: Nasal carriage rate and multiple antimicrobial resistance indices of Staphylococcus aureus among healthcare students at the Ahmadu Bello University, Nigeria
Nasal carriage rate and multiple antimicrobial resistance indices of Staphylococcus aureus among healthcare students at the Ahmadu Bello University, Nigeria Open
Background: Healthcare students could harbour multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus (MRSA). There is a need to understand the extent and factors associated with nasal carriage of these strains.Objective:…
View article: Comparison of pentazocine and pethidine for the treatment of shivering following subarachnoid block
Comparison of pentazocine and pethidine for the treatment of shivering following subarachnoid block Open
Pethidine is one of the known drugs for treating post-spinal shivering; however, it is a controlled drug. Pentazocine, a specific kappa agonist, is widely available in West Africa and is not yet a controlled drug. A randomized, double-blin…
View article: Comparison of motor block in continuous epidural infusion <i>vs</i> intermittent epidural bolus using bupivacaine with fentanyl for labour analgesia
Comparison of motor block in continuous epidural infusion <i>vs</i> intermittent epidural bolus using bupivacaine with fentanyl for labour analgesia Open
This study aimed to compare the motor blocking effect of Continuous Epidural Infusion (CEI) vs Intermittent Epidural Bolus (IEB) for labour analgesia using bupivacaine 0.0625% and fentanyl 4 μg/ml. Sixty primigravida patients were divided …
View article: B-Mode Ultrasound Grading of Cryptogenic Steatotic Liver Disease and Association with the Level of Sun Exposure in Zaria, Nigeria: A Case-Control Study.
B-Mode Ultrasound Grading of Cryptogenic Steatotic Liver Disease and Association with the Level of Sun Exposure in Zaria, Nigeria: A Case-Control Study. Open
The study shows that limited sun exposure is significantly associated with developing CSLD among Nigerians in Zaria. There is also a significant independent risk factor.
View article: Integrated rapid risk assessment for dengue fever in settings with limited diagnostic capacity and uncertain exposure: Development of a methodological framework for Tanzania
Integrated rapid risk assessment for dengue fever in settings with limited diagnostic capacity and uncertain exposure: Development of a methodological framework for Tanzania Open
Background Dengue fever is one of the world’s most important re-emerging but neglected infectious diseases. We aimed to develop and evaluate an integrated risk assessment framework to enhance early detection and risk assessment of potentia…
View article: Methodological framework for early detection of dengue outbreaks in Tanzania
Methodological framework for early detection of dengue outbreaks in Tanzania Open
Background Dengue fever is a major public health problem because it is a widespread and rapidly transmitted mosquito-borne viral disease. We developed a framework for early detection of dengue outbreaks in Tanzania, starting with detection…
View article: Exploring the Impact of Sleep Duration on Cryptogenic Steatotic Liver Disease: A Nigerian Case–control Study
Exploring the Impact of Sleep Duration on Cryptogenic Steatotic Liver Disease: A Nigerian Case–control Study Open
Background: Cryptogenic steatotic liver disease (CSLD) is a growing public health concern in Nigeria, characterized by its unknown etiology and potential progression to severe liver complications such as cirrhosis and liver cancer, posing …
View article: Assessment of interleukin 6 (IL-6) as a marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria
Assessment of interleukin 6 (IL-6) as a marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria Open
Tuberculosis (TB) remains a significant cause of morbidity and mortality worldwide. Complications of the disease are associated with the host’s inflammatory response. The study aimed to determine the plasma level of interleukin-6 as a biom…
View article: <i>In Vivo</i> Anti-Hepatocellular Carcinoma Effects of the Chloroform Root Extract of <i>Clausena excavata</i> Burm
<i>In Vivo</i> Anti-Hepatocellular Carcinoma Effects of the Chloroform Root Extract of <i>Clausena excavata</i> Burm Open
Liver cancer is the most common cancer among males in Africa. The disease has a poor prognosis and its treatment is associated with toxicity and resistance. For this reason, numerous herbal combinations are being subjected to anticancer sc…
View article: B-Mode Ultrasound Grading of Nonalcoholic Fatty Liver Disease and Association with Intima-media Thickness: A Case–Control Study
B-Mode Ultrasound Grading of Nonalcoholic Fatty Liver Disease and Association with Intima-media Thickness: A Case–Control Study Open
Background: Nonalcoholic fatty liver disease (NAFLD) is the infiltration of the liver cells with fat of up to at least 5% and above. It is the type of fatty infiltration that is, not associated with alcohol intake, and is the “hepatic expr…
View article: Antioxidant potential of resveratrol on plasmodium berghei-induced malaria in diabetic male Wistar rats
Antioxidant potential of resveratrol on plasmodium berghei-induced malaria in diabetic male Wistar rats Open
Objective The aim of this study was to elucidate the antioxidant and antimalarial effects of resveratrol in diabetes and malaria comorbidity. Methods 40 males Wistar rats were divided into 8 groups. Induction of diabetes was done in 7 of t…
View article: Phenotypic Profile and Antibiogram of Biofilm-Producing Bacteria Isolates from Diabetic Foot Ulcers in Zaria, Nigeria
Phenotypic Profile and Antibiogram of Biofilm-Producing Bacteria Isolates from Diabetic Foot Ulcers in Zaria, Nigeria Open
Background: Diabetic foot ulcers (DFUs) present with high morbidity and reduce patient's quality of life. There is a gross paucity of data on biofilm-producing bacteria in DFU Infection in North-Western Nigeria. The study sought to determi…
View article: Roles and challenges of clinical microbiology laboratories in antimicrobial stewardship in resource-limited countries
Roles and challenges of clinical microbiology laboratories in antimicrobial stewardship in resource-limited countries Open
Antimicrobial resistance (AMR) is a major global health challenge, especially in low- and middle-income countries (LMIC). Programs that appropriate antibiotic use such as antimicrobial stewardship, is a global health strategy adopted by th…
View article: Sero-prevalence of IgG and IgA AntispermAntibodies in Men with Infertility AttendingTwo Major Hospitals in Zaria, Nigeria
Sero-prevalence of IgG and IgA AntispermAntibodies in Men with Infertility AttendingTwo Major Hospitals in Zaria, Nigeria Open
Background: Antisperm antibodies (ASA) have been implicated in some male with infertility especially those in which a definite cause could not be found. Also, some studies have attributed a causal relationship to the presence of antisperm …
View article: Deficiency of antioxidants and increased oxidative stress in COVID-19 patients: A cross-sectional comparative study in Jigawa, Northwestern Nigeria
Deficiency of antioxidants and increased oxidative stress in COVID-19 patients: A cross-sectional comparative study in Jigawa, Northwestern Nigeria Open
Introduction: The COVID-19 is a pandemic caused by SARS-CoV-2 which has infected over 74 million people, killing more than 1,600,000 million people around the world as of 17th December 2020. Accumulation of free radicals coupled by weakene…
View article: Leucocytes and Th-associated Cytokine Profile of HIV-Leishmaniasis Co-Infected Persons Attending Abuja Teaching Hospital, Nigeria
Leucocytes and Th-associated Cytokine Profile of HIV-Leishmaniasis Co-Infected Persons Attending Abuja Teaching Hospital, Nigeria Open
Objective: T-helper cells (Th)-1& -2 cytokines homeostasis control or predict clinical outcome of infected persons, especially those with HIV /AIDS. This case-control study evaluated the leucocytes differentials, TNF-alpha, interleukin (IL…
View article: Leveraging on the genomics and immunopathology of SARS-CoV-2 for vaccines development: prospects and challenges
Leveraging on the genomics and immunopathology of SARS-CoV-2 for vaccines development: prospects and challenges Open
The incidence and case-fatality rates (CFRs) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, the etiological agent for Coronavirus Disease 2019 (COVID-19), have been rising unabated. Even though the entire world …
View article: Hypothetic immunopathological impacts of SARS-CoV-2 and HIV co-infection on COVID-19 severity
Hypothetic immunopathological impacts of SARS-CoV-2 and HIV co-infection on COVID-19 severity Open
To the Editor, The world is currently battling with and trying to survive yet another pandemic that threatens human health security. Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease…
View article: Association of Hemoglobin Electrophoretic Phenotype with Human Parvovirus B19 infection among Pregnant Women attending Abuja Tertiary Hospital, Nigeria
Association of Hemoglobin Electrophoretic Phenotype with Human Parvovirus B19 infection among Pregnant Women attending Abuja Tertiary Hospital, Nigeria Open
Association of Hemoglobin Electrophoretic Phenotype with Human Parvovirus B19 infection among Pregnant Women attending Abuja Tertiary Hospital, Nigeria
View article: Distribution of hepatitis B virus-positive individuals in Zaria, Nigeria, according to risk-associated practices
Distribution of hepatitis B virus-positive individuals in Zaria, Nigeria, according to risk-associated practices Open
Objective: An estimated 75% of Nigerians are at risk of hepatitis B virus (HBV) exposure. In an attempt to reduce the menace, the assessment of risk factors associated with HBV infection and general perception of infected individuals is a …
View article: Leucocytes and Th-associated cytokine profile of HIV-leishmaniasis coinfected patients attending the Abuja Teaching Hospital, Nigeria
Leucocytes and Th-associated cytokine profile of HIV-leishmaniasis coinfected patients attending the Abuja Teaching Hospital, Nigeria Open
Introduction. T helper cells (Th)-1 and -2 cytokines homeostasis control or predict clinical outcome of infected persons, especially those with HIV/AIDS. This case-control study evaluated the leucocyte differentials, TNF-α, IL-2 and -10 le…
View article: Genetic diversity of human immunodeficiency virus-1 in Nigeria: 2002–2017 – systematic review and meta-analysis
Genetic diversity of human immunodeficiency virus-1 in Nigeria: 2002–2017 – systematic review and meta-analysis Open
Nigeria was ranked second highest country with human immunodeficiency virus (HIV) burden worldwide. HIV-1 subtypes and circulating recombinant forms genetic variability affect the protease and reverse transcriptase genes which code for vir…
View article: An elevated 8-isoprostaglandin F2 alpha (8-iso-PGF2α) in COVID-19 subjects co-infected with malaria
An elevated 8-isoprostaglandin F2 alpha (8-iso-PGF2α) in COVID-19 subjects co-infected with malaria Open
conclusively, SARS-COV-2 patients co-infected with malaria might be predisposed to oxidative stress and low Alphatocopherol. The increase in oxidative stress is proportional to malaria parasite density and inversely related to Alphatocophe…
View article: Clinical and epidemiological significance of RT-PCR and non-structural glycoprotein-1 assays in the diagnosis of dengue virus infections
Clinical and epidemiological significance of RT-PCR and non-structural glycoprotein-1 assays in the diagnosis of dengue virus infections Open
Background: Due to the rapid geographic expansion, dengue has attracted much global attention. Hence, many research outputs have emanated from clinical and epidemiological studies. However, most of these studies, especially those from low-…
View article: Evaluation of hepatitis B viremia and corresponding antibodies among infected patients attending Abuja Teaching Hospital, Nigeria
Evaluation of hepatitis B viremia and corresponding antibodies among infected patients attending Abuja Teaching Hospital, Nigeria Open
In most under-developed and developing countries, diagnosis and treatment of hepatitis B relied mainly on detection of hepatitis B virus (HBV) serological biomarkers. The reliability of these markers in comparison with HBV DNA viral load i…
View article: Evaluation of apoptotic protease-activating Factor-1 and cluster of Differentiation-4<sup>+</sup> T-Cell counts in patients-infected with mycobacterium tuberculosis in Bauchi, Nigeria
Evaluation of apoptotic protease-activating Factor-1 and cluster of Differentiation-4<sup>+</sup> T-Cell counts in patients-infected with mycobacterium tuberculosis in Bauchi, Nigeria Open
Findings from this study showed a lower T-cell immune function during TB infection. However, Apaf-1 has no relevance on TB progression and control.
View article: Pattern of prevalent Hepatitis B virus genotypes in Zaria, Nigeria
Pattern of prevalent Hepatitis B virus genotypes in Zaria, Nigeria Open
In most (99.1%) of the mixed-infection were a combination of genotype E, the predominant genotype, with other genotypes predominantly genotype B. HBV genotypes E, B, A, C and D are the prevalent genotypes in Zaria, Nigeria, as they occur i…