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View article: Clinical effectiveness and safety of vedolizumab versus infliximab in biologic-naïve patients with ulcerative colitis: A comparative real-world multicentric observational study
Clinical effectiveness and safety of vedolizumab versus infliximab in biologic-naïve patients with ulcerative colitis: A comparative real-world multicentric observational study Open
Both VDZ and IFX are effective in biologic-naïve UC patients, however VDZ demonstrated superior endoscopic outcomes, higher treatment persistence, and a better safety profile, supporting its use as a first-line therapy.
View article: P1209 Temporal trends in surgery and hospitalization rates for crohn's disease in Brazil: A population-based study
P1209 Temporal trends in surgery and hospitalization rates for crohn's disease in Brazil: A population-based study Open
Background Crohn's Disease (CD) is a chronic inflammatory condition of the gastrointestinal tract, primarily affecting young adults and adolescents. Biological therapies have advanced CD management, reducing hospitalizations and surgeries.…
View article: Belo Monte Dam impacts: Protagonism of local people in research and monitoring reveals ecosystem service decay in Amazonian flooded vegetation
Belo Monte Dam impacts: Protagonism of local people in research and monitoring reveals ecosystem service decay in Amazonian flooded vegetation Open
The Amazonian river-floodplain systems face unprecedented threats from the construction of hydroelectric power plants aimed at meeting Brazil's energy demands. However, evidence suggests that the long-term economic, social, and environment…
View article: Temporal Trends in Surgery and Hospitalization Rates for Crohn’s Disease in Brazil: A Population-Based Study
Temporal Trends in Surgery and Hospitalization Rates for Crohn’s Disease in Brazil: A Population-Based Study Open
Introduction Biological therapy has transformed the natural course of inflammatory bowel disease, but there are still controversies regarding its potential to reduce surgical rates for Crohn’s disease (CD). This study, conducted with the s…
View article: High-Intensity Laser Therapy – An Option for Managing the Pain in Anal Fissures
High-Intensity Laser Therapy – An Option for Managing the Pain in Anal Fissures Open
Introduction: Anal fissures (AFs) are a prevalent pathology. Although internal lateral sphincterotomy is still the gold-standard surgery for treating chronic AFs, this procedure is associated with a considerable risk of anal incontinence. …
View article: Belo Monte Dam impacts: Protagonism of local people in research and monitoring reveals ecosystem service decay in Amazonian flooded vegetation
Belo Monte Dam impacts: Protagonism of local people in research and monitoring reveals ecosystem service decay in Amazonian flooded vegetation Open
The Amazonian river-floodplain systems face unprecedented threats from the construction of hydroelectric power plants aimed at meeting Brazil's energy demands. However, evidence suggests that the long-term economic, social, and environment…
View article: Covid-19 Pandemic Increased the Number of Ostomies Performed in the Mid-west of Santa Catarina
Covid-19 Pandemic Increased the Number of Ostomies Performed in the Mid-west of Santa Catarina Open
Introduction Intestinal ostomy represents the externalization of the intestine to the abdominal wall. Objective To analyze the clinical and epidemiological profile of patients who underwent intestinal ostomy construction from 2010 to 2023 …
View article: Advanced therapy of extraintestinal manifestations: A case report
Advanced therapy of extraintestinal manifestations: A case report Open
Inflammatory Bowel Disease (IBD) can trigger a variety of signs and symptoms that affect tissues adjacent to the intestine, known as Extra Intestinal Manifestations (EIM), which can significantly impact quality of life, work performance an…
View article: Combination of biologicals and small molecules in the treatment of extra intestinal manifestations due to inflammatory bowel disease
Combination of biologicals and small molecules in the treatment of extra intestinal manifestations due to inflammatory bowel disease Open
Extraintestinal Manifestations (EIM) of Inflammatory Bowel Disease (IBD) consist of inflammatory processes in patients with IBD outside the Gastrointestinal Tract (GIT). They are present in more than 50% of patients with IBD and their path…
View article: Clinical factors associated with severity in patients with inflammatory bowel disease in Brazil based on 2-year national registry data from GEDIIB
Clinical factors associated with severity in patients with inflammatory bowel disease in Brazil based on 2-year national registry data from GEDIIB Open
The Brazilian Organization for Crohn's Disease and Colitis (GEDIIB) established a national registry of inflammatory bowel disease (IBD). The aim of the study was to identify clinical factors associated with disease severity in IBD patients…
View article: TRENDS IN INFLAMMATORY BOWEL DISEASE INCIDENCE AND PREVALENCE ACROSS EPIDEMIOLOGIC STAGES: A GLOBAL SYSTEMATIC REVIEW WITH META-ANALYSIS
TRENDS IN INFLAMMATORY BOWEL DISEASE INCIDENCE AND PREVALENCE ACROSS EPIDEMIOLOGIC STAGES: A GLOBAL SYSTEMATIC REVIEW WITH META-ANALYSIS Open
BACKGROUND Rising incidence and prevalence of inflammatory bowel disease (IBD) observed historically in early-industrialized regions now also appear in newly-industrialized and emerging regions. The epidemiology of IBD has been proposed to…
View article: MODELING THE TRANSITION TO THE FOURTH EPIDEMIOLOGIC STAGE OF INFLAMMATORY BOWEL DISEASE: PREVALENCE EQUILIBRIUM
MODELING THE TRANSITION TO THE FOURTH EPIDEMIOLOGIC STAGE OF INFLAMMATORY BOWEL DISEASE: PREVALENCE EQUILIBRIUM Open
BACKGROUND A theoretical framework for population-level transition across four epidemiologic stages has been proposed for inflammatory bowel disease (IBD): 1. Emergence (low incidence/prevalence); 2. Acceleration in Incidence (rapid rising…
View article: MACHINE LEARNING CLASSIFICATION OF THE EPIDEMIOLOGIC STAGES OF INFLAMMATORY BOWEL DISEASE ACROSS GEOGRAPHY AND TIME
MACHINE LEARNING CLASSIFICATION OF THE EPIDEMIOLOGIC STAGES OF INFLAMMATORY BOWEL DISEASE ACROSS GEOGRAPHY AND TIME Open
BACKGROUND Epidemiologic stages of inflammatory bowel disease (IBD) have been proposed: 1. Emergence (low incidence and prevalence); 2. Acceleration in Incidence (rapidly rising incidence, low prevalence); and 3. Compounding Prevalence (st…
View article: The Global Evolution of Inflammatory Bowel Disease across Four Epidemiologic Stages
The Global Evolution of Inflammatory Bowel Disease across Four Epidemiologic Stages Open
During the 20th century, inflammatory bowel disease (IBD) was considered a disease of early-industrialized regions in North America, Europe, and Oceania. At the turn of the 21st century, incidence of IBD increased in newly-industrialized a…
View article: STRUCTURAL EVALUATION OF INFLAMMATORY BOWEL DISEASE COMPREHENSIVE CARE UNITS IN BRAZIL
STRUCTURAL EVALUATION OF INFLAMMATORY BOWEL DISEASE COMPREHENSIVE CARE UNITS IN BRAZIL Open
Background: The most efficient way to prevent complications from inflammatory bowel disease (IBD) is to provide patients with optimized care. Nonetheless, in Brazil, there is no validated methodology for evaluating health services recogniz…
View article: P840 Structural evaluation of Inflammatory Bowel Disease Comprehensive Care Units in Brazil
P840 Structural evaluation of Inflammatory Bowel Disease Comprehensive Care Units in Brazil Open
Background In Brazil there is no methodology for evaluating health services recognized as Comprehensive Care Units (CCU), making it difficult to assess the quality of care provided for IBD patients. Aims: Map the distribution of this units…
View article: SECOND BRAZILIAN CONSENSUS ON THE MANAGEMENT OF CROHN’S DISEASE IN ADULTS: A CONSENSUS OF THE BRAZILIAN ORGANIZATION FOR CROHN’S DISEASE AND COLITIS (GEDIIB)
SECOND BRAZILIAN CONSENSUS ON THE MANAGEMENT OF CROHN’S DISEASE IN ADULTS: A CONSENSUS OF THE BRAZILIAN ORGANIZATION FOR CROHN’S DISEASE AND COLITIS (GEDIIB) Open
The medical recommendations (pharmacological and non-pharmacological interventions) were mapped according to the stage of treatment and severity of the disease in three domains: management and treatment (drug and surgical interventions), c…
View article: SECOND BRAZILIAN CONSENSUS ON THE MANAGEMENT OF ULCERATIVE COLITIS IN ADULTS: A CONSENSUS OF THE BRAZILIAN ORGANIZATION FOR CROHN’S DISEASE AND COLITIS (GEDIIB)
SECOND BRAZILIAN CONSENSUS ON THE MANAGEMENT OF ULCERATIVE COLITIS IN ADULTS: A CONSENSUS OF THE BRAZILIAN ORGANIZATION FOR CROHN’S DISEASE AND COLITIS (GEDIIB) Open
The medical recommendations (pharmacological and non-pharmacological) were mapped according to the stage of treatment and severity of the disease onto three domains: management and treatment (drug and surgical interventions), criteria for …
View article: SURGICAL MANAGEMENT OF ADULT CROHN’S DISEASE AND ULCERATIVE COLITIS PATIENTS: A CONSENSUS FROM THE BRAZILIAN ORGANIZATION OF CROHN’S DISEASE AND COLITIS (GEDIIB)
SURGICAL MANAGEMENT OF ADULT CROHN’S DISEASE AND ULCERATIVE COLITIS PATIENTS: A CONSENSUS FROM THE BRAZILIAN ORGANIZATION OF CROHN’S DISEASE AND COLITIS (GEDIIB) Open
This consensus addressed the most relevant information to guide the decision-making process for adequate surgical management of CD and UC. It synthesizes recommendations developed from evidence-based statements and state-of-art knowledge. …
View article: P831 Clinical factors associated with severity in patients with Inflammatory Bowel Disease in Brazil (On Behalf of GEDIIB)
P831 Clinical factors associated with severity in patients with Inflammatory Bowel Disease in Brazil (On Behalf of GEDIIB) Open
Background Brazil has shown an increase in Inflammatory Bowel Disease (IBD) cases. GEDIIB (Brazilian Organization of Crohn’s Disease and Colitis) established a data platform to create a national registry of IBD patients. The study aimed to…
View article: IBD barriers across the continents: a continent-specific analysis: Latin America
IBD barriers across the continents: a continent-specific analysis: Latin America Open
Latin America (LATAM) is a large region comprising 47 countries and territories. Each one carries a different cultural and historical background, diverse political systems, and a particular approach to healthcare management. There is a lac…
View article: Temporal trends in the epidemiology of inflammatory bowel diseases in the public healthcare system in Brazil: A large population-based study
Temporal trends in the epidemiology of inflammatory bowel diseases in the public healthcare system in Brazil: A large population-based study Open
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View article: Anti-TNF therapy for ulcerative colitis in Brazil: a comparative real-world national retrospective multicentric study from the Brazilian study group of IBD (GEDIIB)
Anti-TNF therapy for ulcerative colitis in Brazil: a comparative real-world national retrospective multicentric study from the Brazilian study group of IBD (GEDIIB) Open
Background Anti-TNF therapy represented a landmark in medical treatment of ulcerative colitis (UC). There is lack of data on the efficacy and safety of these agents in Brazilian patients. The present study aimed to analyze rates of clinica…