Abhijeet D. Kulkarni
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View article: In-vitro Anti-inflammatory Potential of Nelumbo nucifera Rhizomes
In-vitro Anti-inflammatory Potential of Nelumbo nucifera Rhizomes Open
Nelumbo nucifera, commonly known as sacred lotus, is an aquatic plant with significant medicinal properties utilized in traditional Chinese and Indian medicine for centuries. This study investigated the in-vitro anti-inflammatory potential…
View article: 3D SCAFFOLDS BY 3D BIOPRINTING
3D SCAFFOLDS BY 3D BIOPRINTING Open
When it comes to tissue engineering, 3D printing is a crucial technique for creating intricate constructions using biocompatible materials, cells, and supporting elements. The concept of "3D bioprinting" is concerning 3D printing, which ma…
View article: NON-INVASIVE GLUCOMETER
NON-INVASIVE GLUCOMETER Open
One of the most serious illnesses that affect people nowadays is diabetes. The individual's blood sugar level has to be monitored often to treat diabetes. The present methods for measuring blood sugar that is available on the market employ…
View article: Fundamentals of Superparamagnetic Iron Oxide Nanoparticles: Recent Update
Fundamentals of Superparamagnetic Iron Oxide Nanoparticles: Recent Update Open
The medical sciences have mirrored the rapid growth of nanotechnology in recent years. Superparamagnetic iron oxide nanoparticles (IONPs) are a good example. Owing to its unique features, for example, superparamagnetism, higher surface are…
View article: 388 Targeted ovarian cancer immunotherapy through engineering of follicle stimulating hormone receptor (FSHR) antibody to engage T cells
388 Targeted ovarian cancer immunotherapy through engineering of follicle stimulating hormone receptor (FSHR) antibody to engage T cells Open
Background Ovarian cancer is the deadliest gynecologic malignancy, resulting in the highest mortality among cancers of the female reproductive system. The most prevalent subtype of epithelial ovarian cancer (EOC) is high-grade serous cance…
View article: Buccal drug delivery system
Buccal drug delivery system Open
The buccal area of the oral mucosa provides an adorable channel of systemic medication distribution within the mouth mucosa. Drugs are delivered via oral mucosal layer, that has a higher first-pass metabolism and degrades gastrointestinal.…
View article: Nanobubbles: Fundamentals and recent drug delivery applications
Nanobubbles: Fundamentals and recent drug delivery applications Open
The emerging branch in pharmaceutical sciences known as pharmaceutical nanotechnology presents new tools, opportunities and scope, which are expected to have significant applications, in disease diagnostics and therapeutics. There is a gro…
View article: Pre-submission facility correspondence for generic dosage form with an expedited-approval in 8 months
Pre-submission facility correspondence for generic dosage form with an expedited-approval in 8 months Open
PFC (Pre-Submission Facility Correspondence) is the initial submission for an ANDA (Abbreviated New Drug Application), comprising information for the application similar to the original ANDA, and only valid in the United States Agency For …
View article: Oral Fast Disintegrating Films of Phytochemicals: A Novel Drug Delivery System
Oral Fast Disintegrating Films of Phytochemicals: A Novel Drug Delivery System Open
Oral fast disintegrating films (OFDFs) have been developed as a viable alternative to conventional oral solid dosage forms such as tablets, capsules, and syrups for patients who struggle consuming them. OFDFs are thin strips that disintegr…
View article: Ficus religiosa: A beneficial medicinal plant
Ficus religiosa: A beneficial medicinal plant Open
In India, herbs have been the primary means of treatment. The existence of secondary plant metabolites, which are combinations of chemical substances with different amalgams, in one or more sections of medicinal plants confers therapeutic …
View article: Recent advances in phytochemical-based Nano-formulation for drug-resistant Cancer
Recent advances in phytochemical-based Nano-formulation for drug-resistant Cancer Open
The graph of drug resistance in cancer is reportedly increasing in terms of therapeutic efficiency. As per the WHO reports, around 70% of death reported in low- and middle-income countries. The increase in death toll was imparted from impr…
View article: Silymarin Loaded Novel Drug Delivery for Oral and Topical Administration
Silymarin Loaded Novel Drug Delivery for Oral and Topical Administration Open
Silymarin is polyphenolic flavonoid obtained from the seeds of silybum marianum plant. It has various pharmacological properties such as hepatoprotective, anti-inflammatory, antioxidant, anti-carcinogenic, hypolipidemic properties. Silymar…
View article: Nasal In Situ Gel: Novel Approach for Nasal Drug Delivery
Nasal In Situ Gel: Novel Approach for Nasal Drug Delivery Open
Nasal delivery is an alternative to oral or parenteral administration due to certain limitations such as absorption of the drug, drug targeting to particular organs can cause a problem for administration through oral route. The nasal route…
View article: Mucoadhesive Nanoparticles: A Roadmap to Encounter the Challenge of Rapid Nasal Mucociliary Clearance
Mucoadhesive Nanoparticles: A Roadmap to Encounter the Challenge of Rapid Nasal Mucociliary Clearance Open
The modulation of mucoadhesion at the nanoscale is a very challenging task before the formulation scientists. Mucoadhesive nanoparticles are endowed with distinct properties such as increased residence, intimate contact of mucoadhesive dos…
View article: Quinazolino-thiadiazoles as antimicrobial agents
Quinazolino-thiadiazoles as antimicrobial agents Open
In the present research, we report the synthesis and in vitro antimicrobial activity of a new series of novel quinazolino-thiadiazoles as fused pharmacophore (3–20). In general, the results of the in vitro antibacterial activity are encour…
View article: Process intensification for continuous synthesis of performic acid using Corning advanced-flow reactors
Process intensification for continuous synthesis of performic acid using Corning advanced-flow reactors Open
The present paper reports the experimental details for the synthesis of performic acid (PFA) using Corning advanced-flow reactors (AFRs) using formic acid and H 2 O 2 as reactants, and sulfuric acid as homogeneous catalyst. The effect of d…
View article: Polyelectrolyte complexes: mechanisms, critical experimental aspects, and applications
Polyelectrolyte complexes: mechanisms, critical experimental aspects, and applications Open
The polyelectrolyte complexes (PECs) are versatile formulations formed by electrostatic interactions between oppositely charged biopolymers. PECs have been investigated widely by the researchers to explore the virtues of this formulation v…