Abhijeet Pataskar YOU? Author Swipe

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Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation Open

Julien Champagne, Morten M. Nielsen, Xiaodong Feng, Jasmine Montenegro Navarro, Abhijeet Pataskar , et al. · 2025

Prolonged exposure to interferon-gamma (IFNγ) and the associated increased expression of the enzyme indoleamine 2,3-dioxygenase 1 (IDO1) create an intracellular shortage of tryptophan in the cancer cells, which stimulates ribosomal framesh…

Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer Open

Adva Kochavi, Remco Nagel, Pierre-René Körner, Onno B. Bleijerveld, Chun‐Pu Lin , et al. · 2024

Messenger RNA (mRNA) translation is a tightly controlled process frequently deregulated in cancer. Key to this deregulation are transfer RNAs (tRNAs), whose expression, processing and post-transcriptional modifications are often altered in…

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants Open

Chao Yang, Abhijeet Pataskar, Xiaodong Feng, Jasmine Montenegro Navarro, Inés Paniagua , et al. · 2024

ABPEPserver: a web application for documentation and analysis of substitutants Open

Abhijeet Pataskar, Jasmine Montenegro Navarro, Reuven Agami · 2023

Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential Open

Yuval Malka, Ferhat Alkan, Shinyeong Ju, Pierre-René Körner, Abhijeet Pataskar , et al. · 2022

Boosting Antitumor Immunity with an Expanded Neoepitope Landscape Open

Remco Nagel, Abhijeet Pataskar, Julien Champagne, Reuven Agami · 2022

Immune-checkpoint blockade therapy has been successfully applied to many cancers, particularly tumors that harbor a high mutational burden and consequently express a high abundance of neoantigens. However, novel approaches are needed to im…

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants Open

Abhijeet Pataskar, Julien Champagne, Remco Nagel, Juliana C.N. Kenski, Maarja Laos , et al. · 2022

Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors Open

Sebastian M. Dieter, Domenica Lovecchio, Abhijeet Pataskar, Martina K. Zowada, Pierre-René Körner , et al. · 2022

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants Open

Abhijeet Pataskar, Julien Champagne, Remco Nagel, Juliana C.N. Kenski, Maarja Laos , et al. · 2022

Oncogene-dependent sloppiness in mRNA translation Open

Julien Champagne, Abhijeet Pataskar, Naomi Blommaert, Remco Nagel, Demi Wernaart , et al. · 2021

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 9 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 9: Table S8. RNA-seq data analysis of MCF10A-YAP5SA and MCF10A-TRAM2 cells.

Additional file 5 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 5: Table S4. RNA-seq to identify the target genes of validated enhancers.

Additional file 2 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 2: Table S1. CRISPR-YAP-enh-lib sequences.

Additional file 4 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 4: Table S3. CRISPR screen selected hits.

Additional file 10 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 10: Table S9. RNA-seq data analysis of TRAM2-KO in MCF10A-YAP5SA cells.

Additional file 3 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 3: Table S2. CRISPR screen analysis.

Additional file 8 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 8: Table S7. Proteomics data analysis TRAM2-KO in MDA-MB-231 cells.

Additional file 6 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 6: Table S5. Proteomics data analysis of MCF10A-YAP5SA and MCF10A-TRAM2 cells.

Additional file 11 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 11: Table S10. Primers for ChIP-qPCR, 3C, q-PCR and gene knockout.

Additional file 7 of A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis Open

Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel , et al. · 2021

Additional file 7: Table S6. Proteomics data analysis of TRAM2-KO in MCF10A-YAP5SA cells.

Anti-tumour immunity induces aberrant peptide presentation in melanoma Open

Osnat Bartok, Abhijeet Pataskar, Remco Nagel, Maarja Laos, Eden Goldfarb , et al. · 2020

Deciphering the Gene Regulatory Landscape Encoded in DNA Biophysical Features Open

Abhijeet Pataskar, Willem Vanderlinden, Johannes Emmerig, Aditi Singh, Jan Lipfert , et al. · 2019

<span>SLC</span> 1A3 contributes to L‐asparaginase resistance in solid tumors Open

Jianhui Sun, Remco Nagel, Esther A. Zaal, Alejandro P. Ugalde, Ruiqi Han , et al. · 2019

L-asparaginase (ASNase) serves as an effective drug for adolescent acute lymphoblastic leukemia. However, many clinical trials indicated severe ASNase toxicity in patients with solid tumors, with resistant mechanisms not well understood. H…

Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis Open

Florian Noack, Abhijeet Pataskar, Martin Schneider, Frank Buchholz, Vijay Tiwari , et al. · 2019

Dynamic changes in DNA (hydroxy-)methylation are fundamental for stem cell differentiation. However, the signature of these epigenetic marks in specific cell types during corticogenesis is unknown. Moreover, site-specific manipulation of c…

Stage-Specific Transcription Factors Drive Astrogliogenesis by Remodeling Gene Regulatory Landscapes Open

Neha Tiwari, Abhijeet Pataskar, Sophie Péron, Sudhir Thakurela, Sanjeeb Kumar Sahu , et al. · 2018

A broad molecular framework of how neural stem cells are specified toward astrocyte fate during brain development has proven elusive. Here we perform comprehensive and integrated transcriptomic and epigenomic analyses to delineate gene reg…

Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program Open

Marisa Karow, J. Gray Camp, Sven Falk, Tobias Gerber, Abhijeet Pataskar , et al. · 2018

FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development Open

Sanjeeb Kumar Sahu, Neha Tiwari, Abhijeet Pataskar, Yuan Zhuang, Marina E. Borisova , et al. · 2017

ERK signalling modulates epigenome to drive epithelial to mesenchymal transition Open

Mohit Navandar, Angela Garding, Sanjeeb Kumar Sahu, Abhijeet Pataskar, Sandra Schick , et al. · 2017

The series of events that allow the conversion from adherent epithelial cells into migratory cells is collectively known as epithelial-mesenchymal transition (EMT). EMT is employed during embryonic development such as for gastrulation and …

Highlights of the 1st Student Symposium on Computational Genomics Open

Jonas Ibn-Salem, Sascha Meiers, Ole Eigenbrod, Robert Sehlke, Sweta Talyan , et al. · 2017

On 30 November 2016, over 70 junior researchers in computational biology from diverse countries met in Mainz, Germany, for the 1st Student Symposium on Computational Genomics. Overall, the symposium was a great success and featured four ou…

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