Abhipsa Sinha
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View article: Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary table ST1, ST2 and ST3.
View article: Impact of social deprivation upon the preoperative pathway and early surgical outcomes after pancreatoduodenectomy for PDAC and non-PDAC periampullary cancer in England: the Surg-Panc-UK study
Impact of social deprivation upon the preoperative pathway and early surgical outcomes after pancreatoduodenectomy for PDAC and non-PDAC periampullary cancer in England: the Surg-Panc-UK study Open
Across England socioeconomic deprivation does not appear to relate to survival outcomes after PD for periampullary cancer, regardless of histological subtype. This suggests that pancreatic resectional centres are managing health inequality…
View article: ACSL4-mediated H3K9 and H3K27 hyperacetylation upregulates SNAIL to drive TNBC metastasis
ACSL4-mediated H3K9 and H3K27 hyperacetylation upregulates SNAIL to drive TNBC metastasis Open
Triple-negative breast cancer (TNBC) has profound unmet medical need globally for its devastating clinical outcome associated with rapid metastasis and lack of targeted therapies. Recently, lipid metabolic reprogramming especially fatty ac…
View article: Supplementary Table from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells
Supplementary Table from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells Open
Contains supplementary table ST1, ST2 and ST3.
View article: Supplementary Figures from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells
Supplementary Figures from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells Open
Contains supplementary figure S1, S2, S3, S4, S5 and S6.
View article: Supplementary Table from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells
Supplementary Table from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells Open
Contains supplementary table ST1, ST2 and ST3.
View article: Supplementary Figures from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells
Supplementary Figures from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells Open
Contains supplementary figure S1, S2, S3, S4, S5 and S6.
View article: Data from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells
Data from Terminally exhausted CD8+ T cells resistant to PD-1 blockade promote generation and maintenance of aggressive cancer stem cells Open
Heterogeneity within the tumor infiltrating lymphocyte (TIL) population limits immunotherapeutic efficacy against cancer. Between two subpopulations of exhausted CD8+ TILs (progenitor-exhausted, TPEX; terminally-exhausted, TTEX), TTEX cell…
View article: ACSL4 activity drives TNBC metastasis by positively regulating Histone H3 Acetylation mediated SNAIL expression
ACSL4 activity drives TNBC metastasis by positively regulating Histone H3 Acetylation mediated SNAIL expression Open
Triple-Negative Breast Cancer (TNBC) has profound unmet medical need globally for its devastating clinical outcome associated with rapid metastasis and lack of targeted therapies. Recently, lipid metabolic reprogramming has emerged as a ma…
View article: Loss of PERK function promotes ferroptosis by downregulating SLC7A11 (System Xc⁻) in colorectal cancer
Loss of PERK function promotes ferroptosis by downregulating SLC7A11 (System Xc⁻) in colorectal cancer Open
Ferroptosis, a genetically and biochemically distinct form of programmed cell death, is characterised by an iron-dependent accumulation of lipid peroxides. Therapy-resistant tumor cells display vulnerability toward ferroptosis. Endoplasmic…
View article: Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary table ST1, ST2 and ST3.
View article: Supplementary Figures from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Figures from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary figure S1, S2, S3, S4, S5 and S6.
View article: Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary table ST1, ST2 and ST3.
View article: Supplementary Figures from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Figures from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary figure S1, S2, S3, S4, S5 and S6.
View article: Data from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Data from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Heterogeneity within the tumor-infiltrating lymphocytes (TIL) population limits immunotherapeutic efficacy against cancer. Between two subpopulations of exhausted CD8+ TILs (progenitor-exhausted; TPEX, terminally exha…
View article: Supplementary Figures from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Figures from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary figure S1, S2, S3, S4, S5 and S6.
View article: Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary table ST1, ST2 and ST3.
View article: Data from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Data from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Heterogeneity within the tumor-infiltrating lymphocytes (TIL) population limits immunotherapeutic efficacy against cancer. Between two subpopulations of exhausted CD8+ TILs (progenitor-exhausted; TPEX, terminally exha…
View article: Data from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Data from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Heterogeneity within the tumor-infiltrating lymphocytes (TIL) population limits immunotherapeutic efficacy against cancer. Between two subpopulations of exhausted CD8+ TILs (progenitor-exhausted; TPEX, terminally exha…
View article: Supplementary Figures from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Figures from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary figure S1, S2, S3, S4, S5 and S6.
View article: Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
Supplementary Table from Terminally Exhausted CD8<sup>+</sup> T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells Open
Contains supplementary table ST1, ST2 and ST3.
View article: PERK arm of UPR selectively regulates ferroptosis in colon cancer cells by modulating the expression of SLC7A11 (System Xc-)
PERK arm of UPR selectively regulates ferroptosis in colon cancer cells by modulating the expression of SLC7A11 (System Xc-) Open
Ferroptosis, a genetically and biochemically distinct form of programmed cell death, is characterised by an iron-dependent accumulation of lipid peroxides. Therapy-resistant tumor cells display vulnerability toward ferroptosis. Endoplasmic…
View article: EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis
EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis Open
View article: 1439 Terminally exhausted CD8<sup>+</sup>TILs promote aggressive cancer stem cells while concurrently evading anti PD1 therapy
1439 Terminally exhausted CD8<sup>+</sup>TILs promote aggressive cancer stem cells while concurrently evading anti PD1 therapy Open
Background Tumor-infiltrated CD8+T cell (TIL) heterogeneity is serving as one of the major hurdles in successful PD1 therapy. According to recent reports, among two subpopulations of exhausted CD8+TILs, (progenitor-ex…
View article: CXCR4 intracellular protein promotes drug resistance and tumorigenic potential by inversely regulating the expression of Death Receptor 5
CXCR4 intracellular protein promotes drug resistance and tumorigenic potential by inversely regulating the expression of Death Receptor 5 Open
View article: H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis
H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis Open
Triple Negative Breast Cancer (TNBC) is known to have poor prognosis and adverse clinical outcome among all breast cancer subtypes due to the absence of available targeted therapy for it. Emerging literature indicates that epigenetic repro…
View article: Gene isolation, heterologous expression, purification and functional confirmation of sesamin synthase from Sesamum indicum L.
Gene isolation, heterologous expression, purification and functional confirmation of sesamin synthase from Sesamum indicum L. Open
Members of Cytochromes P450 super family of enzymes catalyse important biochemical reactions in plants. Some of these reactions are so important that they contribute to enormous chemical diversity seen in plants. Many unique secondary meta…