Abigail E. Limary
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View article: Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomesodermin
Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomesodermin Open
Tissue-resident memory CD8+T (TRM) cells are a subset of memory T cells positioned at barrier sites, critical for host defense against infection. Recent studies have begun to reveal substantial heterogeneity in CD8+ TRM populations across …
View article: Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes
Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes Open
Tissue-resident memory CD8+ T (TRM) cells are a subset of memory T cells that play a critical role in limiting early pathogen spread and controlling infection. TRM cells exhibit differences across tissues, but their potential heterogeneity…
View article: The long noncoding RNA Malat1 regulates CD8+ T cell differentiation by mediating epigenetic repression
The long noncoding RNA Malat1 regulates CD8+ T cell differentiation by mediating epigenetic repression Open
During an immune response to microbial infection, CD8+ T cells give rise to short-lived effector cells and memory cells that provide sustained protection. Although the transcriptional programs regulating CD8+ T cell differentiation have be…
View article: Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses Open
Single-cell sequencing analyses reveal changes in B and T cell transcriptional states in the context of ulcerative colitis.