Abiy Abebe
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View article: Prenatal developmental toxicity of Urtica simensis essential oil in rat embryos and rat fetuses
Prenatal developmental toxicity of Urtica simensis essential oil in rat embryos and rat fetuses Open
Pregnant women inhaled fresh U. simensis steam vapor to fumigate their bodies, and boiled it for tea. However, the safety of this practice during pregnancy has not yet been reported. This study aimed to evaluate the prenatal developmental …
View article: The link between child dietary diversity and child anemia: The power of colorful plates
The link between child dietary diversity and child anemia: The power of colorful plates Open
Nutritional anemias are the most common causes of anemia worldwide, and the extent is greater in the sub-Saharan African (SSA) region. Dietary diversification is among the strategies to prevent anemia due to nutrient deficiencies. There is…
View article: In vitro antimicrobial and cytotoxic evaluation of leaf, root, and stem extracts of Solanum dasyphyllum and root and stem extracts of Dovyalis abyssinica
In vitro antimicrobial and cytotoxic evaluation of leaf, root, and stem extracts of Solanum dasyphyllum and root and stem extracts of Dovyalis abyssinica Open
Background Plants like Solanum dasyphyllum and Dovyalis abyssinica have been traditionally used to treat ailments such as fevers, asthma, high blood pressure, infections, stomachaches, skin rashes, for their blood-cleansing and anti-venom …
View article: Prevalence of vision impairment among patients with diabetes mellitus in sub-Saharan Africa: A systematic review and meta-analysis
Prevalence of vision impairment among patients with diabetes mellitus in sub-Saharan Africa: A systematic review and meta-analysis Open
Background Diabetes mellitus is a growing global public health challenge, especially in low- and middle-income regions like sub-Saharan Africa, where healthcare resources are often limited. One of its most debilitating complications is vis…
View article: Evaluation of the acute and subacute toxicity of Lepidium sativum L. seed extract on Wistar rats
Evaluation of the acute and subacute toxicity of Lepidium sativum L. seed extract on Wistar rats Open
Introduction: Lepidium sativum L., commonly known as garden cress, is a well-known medicinal plant used in many low- and middle-income communities for their primary healthcare. In Ethiopia, L. sativum seed is traditionally used to address …
View article: The Rights to Remain Silent under Ethiopian legal framework and It’s Implementation: the Case of Bale Zone
The Rights to Remain Silent under Ethiopian legal framework and It’s Implementation: the Case of Bale Zone Open
The main purpose of criminal justice is to provide rehabilitation and correctional facilities for those who have violated the criminal law and enable them to show attitudinal and behavioral changes. To this end, the whole process of detect…
View article: Association Between Maternal Undernutrition and Pre‐Labor Rupture of Membranes in Ethiopia: A Systematic Review and Meta‐Analysis of Observational Studies
Association Between Maternal Undernutrition and Pre‐Labor Rupture of Membranes in Ethiopia: A Systematic Review and Meta‐Analysis of Observational Studies Open
Background and Aims In Ethiopia, pre‐labor rupture of membranes impacts maternal and perinatal health, while maternal undernutrition remains a major public health issue. The findings of previous studies have been inconsistent, and no natio…
View article: Toxic effects of Lepidium sativum seed fixed oil on Wistar albino rats in acute and subacute toxicity models
Toxic effects of Lepidium sativum seed fixed oil on Wistar albino rats in acute and subacute toxicity models Open
Introduction L. sativum L. (family Brassicaceae) is a versatile herbal medicine in Ethiopia. The seed extract is widely employed in traditional medicine, whilst the seed oil is used as edible oil. However, there are no available studies co…
View article: Acute and sub-acute toxicity of ethanol extracts of Hagenia abyssinica and Rumex abyssinicus flowers in Swiss albino mice
Acute and sub-acute toxicity of ethanol extracts of Hagenia abyssinica and Rumex abyssinicus flowers in Swiss albino mice Open
Background Hagenia abyssinica (Bruce) J.F. Gmel (Family: Rosaceae) and Rumex abyssinicus Jacq (Family: Polygonaceae) are valuable medicinal plants traditionally used in Ethiopia to treat various diseases. Recent studies have also demonstra…
View article: In Vitro Antibacterial Activity, Molecular Docking, and ADMET Analysis of Phytochemicals from Roots of Dovyalis abyssinica
In Vitro Antibacterial Activity, Molecular Docking, and ADMET Analysis of Phytochemicals from Roots of Dovyalis abyssinica Open
Dovyalis abyssinica is widely used in Ethiopia for treating various human ailments, yet its pharmacological properties and chemical composition remain largely unexplored. The chromatographic separation of D. abyssinica roots extract afford…
View article: Antibacterial activity of secondary metabolites from the roots of Solanum dasyphyllum: A combined in vitro and in silico study
Antibacterial activity of secondary metabolites from the roots of Solanum dasyphyllum: A combined in vitro and in silico study Open
Solanum dasyphyllum is widely utilized for folk medicine in Ethiopia. The chromatographic separation of root extract of S. dasyphyllum led to the isolation of six compounds: tremulacin (1), scopoletin (2), stigmasterol (3), β-sitosterol (4…
View article: Ethnomedicine, antibacterial activity, antioxidant potential and phytochemical screening of selected medicinal plants in Dibatie district, Metekel zone, western Ethiopia
Ethnomedicine, antibacterial activity, antioxidant potential and phytochemical screening of selected medicinal plants in Dibatie district, Metekel zone, western Ethiopia Open
Background Medicinal plants play a major role in the delivery of healthcare, particularly among the rural population of Ethiopia. Plant extracts and their bioactive compounds have been utilized for the treatment of several diseases. This s…
View article: Antibacterial activity and phytochemical screening of traditional medicinal plants most preferred for treating infectious diseases in Habru District, North Wollo Zone, Amhara Region, Ethiopia
Antibacterial activity and phytochemical screening of traditional medicinal plants most preferred for treating infectious diseases in Habru District, North Wollo Zone, Amhara Region, Ethiopia Open
Ethiopia’s healthcare system relies on traditional medicinal practices that use medicinal plants to treat human and livestock ailments. However, the lack of empirical validation regarding the efficacy of these treatments against specific i…
View article: Toxicological evaluation of chronic oral administration of Justicia schimperiana (Hochst. ex Nees) T. Anderson leaf 80% methanolic extract in Wistar albino rats
Toxicological evaluation of chronic oral administration of Justicia schimperiana (Hochst. ex Nees) T. Anderson leaf 80% methanolic extract in Wistar albino rats Open
Six months oral administration in Wistar albino rats in this experiment indicated that Justicia schimperiana is relatively safe at lower and medium doses. However, increased liver enzymes, increased kidney function tests and decreased red …
View article: Embryo and Fetal Toxic Effects of the Hydroethanol Extract of <i>Urtica simensis</i> Hochst. Ex. A. Rich Leaves in Pregnant Rats
Embryo and Fetal Toxic Effects of the Hydroethanol Extract of <i>Urtica simensis</i> Hochst. Ex. A. Rich Leaves in Pregnant Rats Open
Introduction: Urtica simensis has been used to treat various diseases such as malaria, hypertension, diabetes, gonorrhea, gastritis, body swelling, and wound infections. However, the safety of consuming U. simensis leaves during pregnancy …
View article: A 3-month-old male infant with Goldenhar syndrome: A clinical case report from Woldia, Northeast Ethiopia
A 3-month-old male infant with Goldenhar syndrome: A clinical case report from Woldia, Northeast Ethiopia Open
Goldenhar syndrome is a multifactorial congenital anomaly that involves structures that develop from the first and second pharyngeal arches. In this report, we present a clinical case of a 3-month-old male infant diagnosed with Goldenhar s…
View article: Evaluation of Anti-Inflammatory Activity of the Methanol Extracts of Premna schimperi Engl (Lamiaceae) Leaves in Rats
Evaluation of Anti-Inflammatory Activity of the Methanol Extracts of Premna schimperi Engl (Lamiaceae) Leaves in Rats Open
Premna schimperi displayed significant anti-inflammatory activity. The tested doses inhibit the formation of edema, granulomas, and exudates.
View article: Antidiarrheal Activities of the Methanol Leaf Extracts of Olinia rochetiana (Oliniaceae) Against Castor Oil-Induced Diarrhea in Mice
Antidiarrheal Activities of the Methanol Leaf Extracts of Olinia rochetiana (Oliniaceae) Against Castor Oil-Induced Diarrhea in Mice Open
In the current investigation, O. rochetiana showed significant antidiarrheal activity with no symptoms of toxicity in mice.
View article: Antibacterial Activity of a Phenylpropanoid from the Root Extract of Carduus leptacanthus Fresen
Antibacterial Activity of a Phenylpropanoid from the Root Extract of Carduus leptacanthus Fresen Open
Background. The emergence and rapid spread of antimicrobial drug-resistance microorganisms exacerbate the treatment of infectious diseases, underscoring the importance of finding new, safe, and effective drugs. In Ethiopia, the roots of Ca…
View article: School Feeding and Nutritional Status of Students in Dubti District, Afar, Northeast Ethiopia: Comparative Cross-Sectional Study
School Feeding and Nutritional Status of Students in Dubti District, Afar, Northeast Ethiopia: Comparative Cross-Sectional Study Open
The magnitude of stunting and thinness in school fed students is found to be lower, but overnutrition is higher than non-school fed. Grade level of students and diet selection information were determinants that affected the nutritional sta…
View article: Toxic effect of Syzygium guineense ethanolic extract on female reproduction in rats: An evidence from a 10 week repeated-dose toxicity study
Toxic effect of Syzygium guineense ethanolic extract on female reproduction in rats: An evidence from a 10 week repeated-dose toxicity study Open
Administration of high doses of S. guineense could be toxic to some aspects of the reproductive system of female rats and might also affect reproduction. Therefore, consuming high dose of S. guineense leaves is not recommended.
View article: Toxic effects of 70% ethanol extract of Moringa stenopetala leaf (Baker f.) Cufod. (Moringaceae) on fetus and placenta of pregnant Wistar rats
Toxic effects of 70% ethanol extract of Moringa stenopetala leaf (Baker f.) Cufod. (Moringaceae) on fetus and placenta of pregnant Wistar rats Open
Background Moringa stenopetala leaves (Baker f.) Cufod. (Moringaceae) are used as a staple food and traditional medicine for treating various diseases like malaria, hypertension, stomach pain, diabetes, elevated cholesterol, and removing t…
View article: Nutrient Density and Microbial Safety of Open-Air-Dried Beef Meat and Its Biochemical and Organ Histopathology Effects in Albino Rats: A Promising Ingredient for Complementary Food Formulation
Nutrient Density and Microbial Safety of Open-Air-Dried Beef Meat and Its Biochemical and Organ Histopathology Effects in Albino Rats: A Promising Ingredient for Complementary Food Formulation Open
Introduction. Dried beef meat is a major source of essential fatty acids, minerals, and vitamins that are digestible and absorbable, thus could be a potential source of nutrients in complementary food formulations. Composition, microbial s…
View article: Analgesic and Anti-Inflammatory Activities of 80% Methanol Extract and Solvent Fractions of Ehretia cymosa Thonn (Boraginaceae) Leaves in Rodents
Analgesic and Anti-Inflammatory Activities of 80% Methanol Extract and Solvent Fractions of Ehretia cymosa Thonn (Boraginaceae) Leaves in Rodents Open
From the results of this investigation, it can be stated that 80% methanol extract, aqueous, ethyl acetate and chloroform fractions of E. cymosa exhibited considerable analgesic and anti-inflammatory activities, supporting the plant's trad…
View article: Acute and Subacute Toxicity of Rhamnus prinoides Leaves on Histopathology of Liver, Kidney, and Brain Tissues, and Biochemical Profile of Rats
Acute and Subacute Toxicity of Rhamnus prinoides Leaves on Histopathology of Liver, Kidney, and Brain Tissues, and Biochemical Profile of Rats Open
Rhamnus prinoides is used as a traditional medicinal plant to treat pneumonia, sprain, gonorrhea, rheumatism, and ringworm infections as well as for the preparation of local beverages in Ethiopia. It has a widespread antioxidant, antimalar…