Abraham Hang
YOU?
Author Swipe
View article: Effects of Imposed Defocus on Inhibitor of DNA-Binding Gene Expression in Chick Posterior Ocular Tissues
Effects of Imposed Defocus on Inhibitor of DNA-Binding Gene Expression in Chick Posterior Ocular Tissues Open
Inhibitors of DNA-binding genes (Ids) are key downstream targets of bone morphogenetic proteins (BMPs), gene expression of which is differentially regulated in the chick retinal pigment epithelium (RPE) during altered eye growth. The curre…
View article: Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes
Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes Open
We identified 12 mouse genes with significant late-adult abnormal retinal pathology, eight of which have not been previously implicated in either mouse or human retinal physiology or pathology. These serve as novel retinal disease gene can…
View article: Intravitreal Faricimab for Previously Treated Neovascular Age-Related Macular Degeneration
Intravitreal Faricimab for Previously Treated Neovascular Age-Related Macular Degeneration Open
In previously treated nAMD eyes, intravitreal faricimab was associated with increased mean treatment interval and decreased CST but no improvement in mean BCVA. The benefit of faricimab on CST reduction may be diminished in eyes previously…
View article: Intravitreal faricimab for previously treated neovascular age-related macular degeneration
Intravitreal faricimab for previously treated neovascular age-related macular degeneration Open
Background/Objectives: To report our real-world experience using intravitreal faricimab, a novel anti-vascular endothelial growth factor (anti-VEGF) therapy, in eyes with neovascular age-related macular degeneration (nAMD) previously treat…
View article: Surgical Drainage of Large Macular Cystoid Spaces in Coats Disease
Surgical Drainage of Large Macular Cystoid Spaces in Coats Disease Open
Purpose: To describe an option of surgically draining large macular cystoid spaces in a patient with Coats disease. Methods: A case and its findings were analyzed. Results: A standard pars plana vitrectomy was performed to aspirate large m…
View article: Intravitreal Anti-Vascular Endothelial Growth Factor Therapies for Retinal Disorders
Intravitreal Anti-Vascular Endothelial Growth Factor Therapies for Retinal Disorders Open
Vascular endothelial growth factors (VEGFs) are key mediator of retinal and choroidal neovascularization as well as retinal vascular leakage leading to macular edema. As such, VEGF plays an important role in mediating visually significant …
View article: Predictive Factors of Research Productivity among Ophthalmology Residents: A Benchmark Analysis
Predictive Factors of Research Productivity among Ophthalmology Residents: A Benchmark Analysis Open
Introduction Positive and negative associations between prior publications and future research productivity is described in other fields, but no such analysis exists for ophthalmology. We conducted a study to determine characteristics of r…
View article: Retinal defocus and <scp>form‐deprivation</scp> induced regional differential gene expression of bone morphogenetic proteins in chick retinal pigment epithelium
Retinal defocus and <span>form‐deprivation</span> induced regional differential gene expression of bone morphogenetic proteins in chick retinal pigment epithelium Open
We previously reported bidirectional gene expression regulation of the Bone Morphogenetic Proteins ( BMP2 , 4 , and 7 ) in chick retinal pigment epithelium (RPE) in response to imposed optical defocus and form‐deprivation (FD). This study …
View article: Differential gene expression of BMP2 and BMP receptors in chick retina & choroid induced by imposed optical defocus
Differential gene expression of BMP2 and BMP receptors in chick retina & choroid induced by imposed optical defocus Open
Recent studies have demonstrated the defocus sign-dependent, bidirectional gene expression regulation of bone morphogenetic proteins, BMP2, 4 and 7 in chick RPE. In this study, we examined the effects of imposed positive (+10 D) and negati…