Abraham Oomman
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View article: Study Design and Baseline Characteristics of the VERINA Study: Phase IV Evidence of Vericiguat for Worsening Heart Failure Management
Study Design and Baseline Characteristics of the VERINA Study: Phase IV Evidence of Vericiguat for Worsening Heart Failure Management Open
Clinical Trials Registry of India (CTRI/2022/11/047636).
View article: Intelligent Decision Support System Facilitating Early Detection of Cardiovascular Disease
Intelligent Decision Support System Facilitating Early Detection of Cardiovascular Disease Open
Background Cardiovascular disease (CVD) remains the primary cause of mortality worldwide, with higher fatality rates in India. Multi-modal diagnostics integrating electrocardiogram (ECG) analysis, cardiac biomarkers, and region-specific in…
View article: Indian Interventional Cardiologists’ Perspectives on De-escalating Dual to Single Antiplatelet Therapy in High Bleeding Risk (HBR) Patients
Indian Interventional Cardiologists’ Perspectives on De-escalating Dual to Single Antiplatelet Therapy in High Bleeding Risk (HBR) Patients Open
This study presents Indian interventional cardiologists' perspectives on de-escalation strategies, including transitioning from DAPT to SAPT, to reduce bleeding complications, while ensuring adequate ischemic protection in patients with HB…
View article: Pneumococcal Disease Risk and Vaccination Consensus in Cardiac Conditions: Expert Group Recommendations Based on Modified Delphi Consensus Method
Pneumococcal Disease Risk and Vaccination Consensus in Cardiac Conditions: Expert Group Recommendations Based on Modified Delphi Consensus Method Open
Introduction Individuals with chronic cardiac conditions are at increased risk for developing pneumococcal diseases. In this study, we aim to develop an evidence-based consensus document on the use of pneumococcal vaccines in individuals w…
View article: Myocardial Infarction Following Short-term Cessation of Dabigatran
Myocardial Infarction Following Short-term Cessation of Dabigatran Open
Dabigatran is indicated for stroke prevention for nonvalvular atrial fibrillation. Dabigatran is a double-edged sword as myocardial infarctions (MIs) were found increased and even cessation can result in MIs. The present report documents M…
View article: Very early discharge of LOw-Risk ST elevation myocardial infarction patients after successful primary percutaneous coronary intervention (VEDLOR-STEMI) study
Very early discharge of LOw-Risk ST elevation myocardial infarction patients after successful primary percutaneous coronary intervention (VEDLOR-STEMI) study Open
This VEDLOR-STEMI study assessed the safety and efficacy of very-early discharge (VED- ≤ 48 h) after primary percutaneous coronary intervention (PPCI) for patients with ST elevation myocardial infarction who are considered low risk and com…
View article: A Right-atrial Variant of Wild-type Transthyretin Cardiac Amyloidosis
A Right-atrial Variant of Wild-type Transthyretin Cardiac Amyloidosis Open
Amyloidosis is caused by extracellular deposition of amyloid protein in various organs and tissues. Light-chain amyloidosis is the most common systemic amyloidosis, whereas transthyretin amyloid cardiomyopathy is emerging as the underdiagn…
View article: Ambulatory blood pressure monitoring for Indian hypertensive patients-where we stand right now?
Ambulatory blood pressure monitoring for Indian hypertensive patients-where we stand right now? Open
Hypertension remains a leading cause of morbidity and mortality globally, with significant impacts on public health due to its role in cardiovascular disease and stroke. In India, hypertension prevalence is estimated at 35.5%, emphasizing …
View article: Arrhythmia and Time of Day in Maintenance Hemodialysis: Secondary Analysis of the Monitoring in Dialysis Study
Arrhythmia and Time of Day in Maintenance Hemodialysis: Secondary Analysis of the Monitoring in Dialysis Study Open
Clinically significant arrhythmias showed strong diurnal patterns with a maximal peak between 12:00 AM and 5:59 AM and noon. Although overall arrhythmia rates were similar, the peak rate occurred overnight in individuals without heart fail…
View article: Very Early Discharge of LOw-Risk ST Elevation MI patients after successful primary percutaneous coronary intervention (VEDLOR-STEMI) study
Very Early Discharge of LOw-Risk ST Elevation MI patients after successful primary percutaneous coronary intervention (VEDLOR-STEMI) study Open
Background Current European guidelines recommend discharging low-risk STEMI patients after successful primary PCI at 48-72 hours, based on meta-analysis and large observational studies. There is overall trend towards reducing hospital stay…
View article: Prevalence of subclinical coronary artery atherosclerosis in the general population- apollo subclinical coronary atherosclerosis project (ASCAP)
Prevalence of subclinical coronary artery atherosclerosis in the general population- apollo subclinical coronary atherosclerosis project (ASCAP) Open
Background Coronary artery disease (CAD) is a major cause of mortality and morbidity in our country. CAD affects Indian population at least a decade earlier than the people of European ancestry, often impacting the most productive years of…
View article: Initiation, Treatment Response Evaluation, and Safety Monitoring of Angiotensin Receptor/Neprilysin Inhibitors (Sacubitril/Valsartan) in the Management of Heart Failure in India: An Expert Group Recommendations
Initiation, Treatment Response Evaluation, and Safety Monitoring of Angiotensin Receptor/Neprilysin Inhibitors (Sacubitril/Valsartan) in the Management of Heart Failure in India: An Expert Group Recommendations Open
Angiotensin receptor/neprilysin inhibitors (ARNI) have become a pillar of heart failure (HF) management. Clinicians gain practical insight into the use of sacubitril/valsartan in patients with HF with reduced ejection fraction (EF) from a …
View article: The Indian registry on current patient profiles & treatment trends in hypertension (RECORD): One year interim analysis
The Indian registry on current patient profiles & treatment trends in hypertension (RECORD): One year interim analysis Open
Background & objectives: In India, hypertension constitutes a significant health burden. This observational, non-interventional, prospective study was conducted in five centres across India to evaluate the current clinical practices for th…
View article: Bempedoic Acid for Lipid Management in the Indian Population: An Expert Opinion
Bempedoic Acid for Lipid Management in the Indian Population: An Expert Opinion Open
Lipid-lowering is a central theme in the management of patients with atherosclerotic cardiovascular disease (ASCVD) and heterozygous familial hypercholesterolemia (HeFH), with statins being currently used as the first-line lipid-lowering a…
View article: Management of non-ischemic dilated cardiomyopathy
Management of non-ischemic dilated cardiomyopathy Open
Heart failure (HF) remains a leading cause of morbidity and mortality globally. For every 23 s, a new case of HF is diagnosed in India. Dilated cardiomyopathy is characterized by dilatation of the left ventricle or both ventricles with imp…
View article: Clinical profile and long-term (10-year) follow-up of patients with amyloid degeneration on valve biopsy during valve replacement surgery
Clinical profile and long-term (10-year) follow-up of patients with amyloid degeneration on valve biopsy during valve replacement surgery Open
Cardiac amyloidosis is one of the most common causes of restrictive heart disease causing diffuse infiltration of heart tissue. Chronic inflammation is one of the causes of amyloidosis. We aim to outline a series of cases over a period of …
View article: Cardiac amyloidosis in South India: A tertiary care centre experience
Cardiac amyloidosis in South India: A tertiary care centre experience Open
Background: Cardiac amyloidosis (CA), a rare entity, is underappreciated as a cause of common cardiac diseases. Most of the data in India focuses on the amyloid light chain (AL) type of amyloidosis. The amyloid transthyretin (ATTR) type is…