Explanipedia

Statement from the frontal fibrosing alopecia international expert alliance: SOFFIA 2024 Open

Nekma Meah, Jane Li, Dmitri Wall, Katherine York, Bevin Bhoyrul , et al. · 2025

Background As the incidence of frontal fibrosing alopecia (FFA) continues to rise, there is a need for an optimal treatment algorithm for FFA. Objective To produce an international consensus statement on the treatment modalities and progno…

Characterization of scalp, eyelash and eyebrow hair regrowth in patients with severe alopecia areata randomized to placebo in brave AA1 and brave AA2 trials Open

Abraham Zlotogorski, Sergio Vañó‐Galván, Bianca Maria Piraccini, Frédérick Durand, Guanglei Yu , et al. · 2024

Background Alopecia areata (AA) is an auto‐immune disorder characterized by non‐scarring hair loss. With the emergence of effective therapies for severe AA, there is a need to better understand the prognosis of untreated AA, specifically t…

Familial oral lichen planus: A new risk group for oral cancer? Open

Rakefet Czerninski, Zinat Awadieh, S. Feldman, Naama Keshet, Abraham Zlotogorski , et al. · 2023

Objective The familial type of oral lichen planus (OLP) is rare, with a paucity of data regarding its clinical significance. Our objective was to characterize patients with familial OLP. Methods Families with at least two members diagnosed…

Integrated safety analysis of baricitinib in adults with severe alopecia areata from two randomized clinical trials Open

Brett King, Arash Mostaghimi, Yutaka Shimomura, Abraham Zlotogorski, Gwang Seong Choi , et al. · 2022

Background Baricitinib, an oral, selective, reversible Janus kinase (JAK)1/JAK2 inhibitor, is an approved treatment for adults with severe alopecia areata (AA) in the USA, European Union and Japan. Objectives To report safety data for bari…

Efficacy of ultraviolet A1 phototherapy for inflammatory, sclerotic and neoplastic dermatological diseases: A 10‐year tertiary referral center experience Open

Shachar Ronen, Yuval Ramot, Abraham Zlotogorski, Rony Shreberk‐Hassidim · 2022

Background Ultraviolet (UV) A1 phototherapy is considered a beneficial treatment for various inflammatory, sclerotic, malignant, and other skin conditions. However, the available data regarding its efficacy for different indications, the p…

Sechs Fälle von Pityriasis rosea nach SARS‐CoV‐2‐Impfung mit BNT162b2 Open

Yuval Ramot, Krassimira Nanova, Sofia‐Maria Faitatziadou, Dania Abu Assab, Yackov Berkun , et al. · 2022

Dermatological adverse events under programmed cell death‐1 inhibitors as a prognostic marker in metastatic melanoma Open

Rony Shreberk‐Hassidim, Lilach Aizenbud, Shalev Lussheimer, Elena Thomaidou, Tali Bdolah‐Abram , et al. · 2022

Melanoma is widely treated with programmed cell death-1 (PD-1) inhibitors. As part of their anti-tumor immunity effect, they increase the susceptibility to cutaneous immune-related adverse events (cIRAE) among other autoimmune effects. To …

Six cases of pityriasis rosea following SARS‐CoV‐2 vaccination with BNT162b2 Open

Yuval Ramot, Krassimira Nanova, Sofia‐Maria Faitatziadou, Dania Abu Assab, Yackov Berkun , et al. · 2022

Permanent chemotherapy-induced alopecia after hematopoietic stem cell transplantation treated with low-dose oral minoxidil Open

Anna Lyakhovitsky, Oz Segal, Alexander Maly, Abraham Zlotogorski, Aviv Barzilai · 2022

Subcutaneous Levodopa Infusion for Parkinson's Disease: 1‐Year Data from the Open‐Label BeyoND Study Open

Werner Poewe, Fabrizio Stocchi, David Arkadir, Georg Ebersbach, Aaron Ellenbogen , et al. · 2021

Background Continuous, subcutaneous (SC) levodopa/carbidopa infusion with ND0612 is under development as a treatment for patients with Parkinson's disease (PD) and motor fluctuations. Objective Evaluate 1‐year safety data. Methods BeyoND i…

Chronic demodicosis in patients with immune dysregulation: An unexpected infectious manifestation of Signal transducer and activator of transcription (STAT)1 gain-of-function Open

Oded Shamriz, Atar Lev, Amos J. Simon, Ortal Barel, Elisheva Javasky , et al. · 2021

Signal transducer and activator of transcription (STAT)1 heterozygous gain-of-function (GOF) mutations are known to induce immune dysregulation and chronic mucocutaneous candidiasis (CMCC). Previous reports suggest an association between d…

Recurrent varicella following SARS‐CoV‐2 vaccination with BNT162b2 Open

Krassimira Nanova, Abraham Zlotogorski, Yuval Ramot · 2021

Wax Stripping and Isotretinoin Treatment: A Warning Not to Be Missed Open

Abraham Zlotogorski · 2021

Can Tofacitinib Offer Protection against COVID-19 Infection? Open

Tal Goldberger, Abraham Zlotogorski · 2021

Dear Editor,We would like to share our experience with a 10-year-old patient with long-standing alopecia areata universalis that was treated with tofacitinib 5 mg BID for 8 months, with excellent clinical response (Fig. 1). Following a lar…

Exacerbation of Hailey-Hailey Disease Following SARS-CoV-2 Vaccination Open

Gil Armoni-Weiss, Sivan Sheffer‐Levi, Liran Horev, Laurent Klapholz, Emily Avitan‐Hersh , et al. · 2021

is missing (Short communication).

The efficacy of off-label IL-5-modulating treatment in rare eosinophil-mediated diseases Open

Oded Shamriz, Alon Y. Hershko, Aviv Talmon, Yaarit Ribak, Anat Scheiman Elazary , et al. · 2020

Multiple Nasal Papules in a 12-year-old Boy: A Quiz Open

Dania Abu Assab, Alexander Maly, Abraham Zlotogorski, Vered Molho‐Pessach · 2020

Hirsutism Induced by Facial Autologous Fat Grafting Open

Yuval Ramot, Tatiana Silyuk, Sari Murad, Abraham Zlotogorski · 2019

Autologous fat grafting (AFG) is a common procedure, which gains popularity for a large number of indications, mainly for reshaping and filling of contour defects. It is considered a safe procedure, with only uncommon and mild complication…

Supplementary Material for: Epidemiology and Comorbidities of Psoriasis among Israeli Adolescents: A Large Cross-Sectional Study Open

Rony Shreberk‐Hassidim, Eran Galili, Ayal Hassidim, Yuval Ramot, Ilan Merdler , et al. · 2019

Background and Aims: Although psoriasis can develop at any age, the data regarding its characteristics in adolescents are sparse. This study was designed to determine the psoriasis prevalence and its associations with the bod…

Dermatology today and tomorrow: from symptom control to targeted therapy Open

Ulrike Blume‐Peytavi, Martine Bagot, Dominique Tennstedt, M. Saint Aroman, Eggert Stockfleth , et al. · 2018

For many decades and until recently, medical approach to dermatologic diseases has been based on the physician's ability to recognize and treat symptoms. Nowadays, advances in the understanding of the biology of diseases and in technologie…

Spontaneous Quick Resolution of Uncombable Hair Syndrome-Like Disease Open

Yuval Ramot, Abraham Zlotogorski, Vered Molho‐Pessach · 2018

Uncombable hair syndrome (UHS) is a unique hair shaft disease characterized by frizzy, straw-colored hair, which is resistant to combing and brushing. Familial cases have been described, and recently mutations in genes related to trichohya…

Meeting Calendar Open

Alessandra Anzai, Neusa Yuriko Sakai Valente, Ricardo Romiti, Karina Lopes Morais, Cintia F. Martins , et al. · 2018

Complete Regrowth of Beard Hair with Ruxolitinib in an Alopecia Universalis Patient Open

Yuval Ramot, Abraham Zlotogorski · 2017

While most alopecia areata (AA) cases resolve spontaneously, the more severe types of AA, alopecia totalis (AT) and alopecia universalis (AU), can be highly resistant to therapy. We report on a 33-year-old ultraorthodox Jewish man with an …

Proceedings of the Ninth World Congress for Hair Research (2015) Open

Wilma F. Bergfeld, Angela M. Christiano, Maria Hordinsky, Victoria Barbosa, Wilma F. Bergfeld , et al. · 2017

Multilesional cutaneous leishmaniasis Open

Yuval Ramot, Abraham Zlotogorski · 2016

A 27-year-old healthy woman presented to the medical centre with a one-month history of widespread skin lesions with slow clinical progression. The lesions appeared on her thighs, shins, lower abdomen and left arm three weeks after she had…

Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production Open

Anja Brehm, Yin Liu, Afzal Sheikh, Bernadette Marrero, Ebun Omoyinmi , et al. · 2016

Autosomal recessive mutations in proteasome subunit β 8 (PSMB8), which encodes the inducible proteasome subunit β5i, cause the immune-dysregulatory disease chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperatur…

Endocrine Focus on H Syndrome Open

Vered Molho‐Pessach, Abraham Zlotogorski · 2016

Alopecia Areata as a Manifestation of Systemic Lymphoma: Report of Two Cases Open

Yuval Ramot, Alexander Gural, Abraham Zlotogorski · 2016

Alopecia areata is a common autoimmune disorder leading to hair loss. It usually affects individuals under the age of 40, and first appearance in older subjects is considered uncommon. Here, we report 2 cases of rapidly progressing alopeci…

Rapid Clearance of Necrolytic Migratory Erythema Following Intravenous Administration of Amino Acids Open

Elena Thomaidou, Avital Nahmias, Leon Gilead, Abraham Zlotogorski, Yuval Ramot · 2015

Rapid Clearance of Necrolytic Migratory Erythema Following Intravenous Administration of Amino AcidsNecrolytic migratory erythema (NME) is a rare paraneoplastic skin disorder, considered the hallmark clinical sign of glucagonoma syndrome.I…

Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production Open

Anja Brehm, Yin Liu, Afzal Sheikh, Bernadette Marrero, Ebun Omoyinmi , et al. · 2015

Autosomal recessive mutations in proteasome subunit β 8 (PSMB8), which encodes the inducible proteasome subunit β5i, cause the immune-dysregulatory disease chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperatur…

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