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View article: Dynamic monitoring of antibody titers in people living with HIV during Omicron epidemic: comparison between unvaccinated and vaccinated individuals
Dynamic monitoring of antibody titers in people living with HIV during Omicron epidemic: comparison between unvaccinated and vaccinated individuals Open
Our findings show the importance of vaccination in enhancing SARS-CoV-2 immunity among PLWH, with the diminishing differences in antibody levels in repeated Omicron reinfections. The results emphasize the need for continuous monitoring usi…
View article: Identification and characteristics of mutations promoting occult HBV infection by ultrasensitive HBsAg assay
Identification and characteristics of mutations promoting occult HBV infection by ultrasensitive HBsAg assay Open
The significance of occult hepatitis B virus (HBV) infection (OBI) has been increasingly recognized while the underlying mechanisms remain incompletely understood. This study aimed to identify high-frequency OBI-related mutations in HBV su…
View article: Acceptance of COVID-19 boosters among hypertensive patients in China: A multicenter cross-sectional study
Acceptance of COVID-19 boosters among hypertensive patients in China: A multicenter cross-sectional study Open
Hypertension, a prevalent chronic disease, has been associated with increased COVID-19 severity. To promote the COVID-19 booster vaccination of hypertensive patients, this study investigated the willingness to receive boosters and the rela…
View article: CDK4/6 inhibitor palbociclib promotes SARS-CoV-2 cell entry by down-regulating SKP2 dependent ACE2 degradation
CDK4/6 inhibitor palbociclib promotes SARS-CoV-2 cell entry by down-regulating SKP2 dependent ACE2 degradation Open
View article: Circulating immune complexes and mutations of HBsAg are associated with the undetectable HBsAg in anti-HBs and HBeAg positive occult hepatitis B virus infection
Circulating immune complexes and mutations of HBsAg are associated with the undetectable HBsAg in anti-HBs and HBeAg positive occult hepatitis B virus infection Open
Introduction Occult hepatitis B virus infection (OBI) is an HBsAg negative state in HBV infection with usually inactive HBV replication. However, there were a minority of individuals with positive HBeAg and anti-HBs among OBI blood donors …
View article: Role of S protein transmembrane domain mutations in the development of occult hepatitis B virus infection
Role of S protein transmembrane domain mutations in the development of occult hepatitis B virus infection Open
Occult HBV infection (OBI) is a special infection status during Hepatitis B virus (HBV) infection. The underlying mechanism of its occurrence remains unclear. This study conducted sequencing analysis on 104 OBI plasma samples and 524 HBsAg…