Ad F. T. M. Verhagen
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View article: Cardiac Surgery during Pregnancy: When and How?
Cardiac Surgery during Pregnancy: When and How? Open
View article: [89Zr]Zr-DFO-avelumab accumulation in resectable non-small cell lung carcinoma indicates a suppressive tumor microenvironment amendable to neoadjuvant avelumab treatment
[89Zr]Zr-DFO-avelumab accumulation in resectable non-small cell lung carcinoma indicates a suppressive tumor microenvironment amendable to neoadjuvant avelumab treatment Open
Background Immune checkpoint inhibitor treatment in non-small cell lung cancer (NSCLC) expands to early stages of disease. The neoadjuvant setting allows to investigate the mechanism-of-action of immune therapy using molecular imaging and …
View article: Correction: ter Woerds et al. Endobronchial Ultrasound Staging During Navigation Bronchoscopy for Peripheral Pulmonary Nodules in the Real World: Which Patients Will Benefit? Cancers 2025, 17, 1700
Correction: ter Woerds et al. Endobronchial Ultrasound Staging During Navigation Bronchoscopy for Peripheral Pulmonary Nodules in the Real World: Which Patients Will Benefit? Cancers 2025, 17, 1700 Open
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View article: Feasibility of intraoperative indocyanine green injection to identify lymph nodes at risk of metastatic disease for early-stage lung cancer
Feasibility of intraoperative indocyanine green injection to identify lymph nodes at risk of metastatic disease for early-stage lung cancer Open
View article: Endobronchial Ultrasound Staging During Navigation Bronchoscopy for Peripheral Pulmonary Nodules in the Real World: Which Patients Will Benefit?
Endobronchial Ultrasound Staging During Navigation Bronchoscopy for Peripheral Pulmonary Nodules in the Real World: Which Patients Will Benefit? Open
Background/Objectives: The prevalence of lung cancer in patients with a peripheral pulmonary nodule referred for navigation bronchoscopy (NB) is high. Combining NB with a systematic EBUS for staging is common practice. We investigated the …
View article: Biocompatibility of a novel lung sealant based on functionalized polyoxazolines in an ovine model of parenchymal lung injury
Biocompatibility of a novel lung sealant based on functionalized polyoxazolines in an ovine model of parenchymal lung injury Open
The NHS-POx patch shows a comparable to favorable biocompatibility profile compared to fibrin patch, and is a potent candidate for clinical lung sealing applications.
View article: Detection of PRKAR1A gene mutations in sporadic cardiac myxomas: a study of 24 cases
Detection of PRKAR1A gene mutations in sporadic cardiac myxomas: a study of 24 cases Open
View article: Diaphragm Dysfunction After Cardiac Surgery
Diaphragm Dysfunction After Cardiac Surgery Open
New postoperative diaphragm elevation occurs in 27% of patients undergoing cardiac surgery. However, new postoperative diaphragm elevation is not associated with a higher incidence of postoperative complications and spontaneous recovery is…
View article: Incidence of Second Primaries and Recurrent Disease in Early-Stage Lung Cancer: What Can We Expect in a Nodule-Care Center Cohort?
Incidence of Second Primaries and Recurrent Disease in Early-Stage Lung Cancer: What Can We Expect in a Nodule-Care Center Cohort? Open
View article: Functional outcome of cell seeded tracheal scaffold after mechanical stress in vitro
Functional outcome of cell seeded tracheal scaffold after mechanical stress in vitro Open
Tracheal tissue engineering is still facing major challenges: realization of efficient vascularization and mechanical properties comparable to native trachea need to be achieved. In this study, we present a strategy for the manufacturing o…
View article: Incidence of early persistent pain after video-assisted thoracoscopic surgery: a single-centre prospective cohort study
Incidence of early persistent pain after video-assisted thoracoscopic surgery: a single-centre prospective cohort study Open
Early persistent postoperative pain is present in 16.2% of patients after VATS. Acute postoperative pain is the strongest risk factor for developing such persistent pain. This underlines that awareness of clinicians for strategies that opt…
View article: An International Registry Study of Early-Stage NSCLC treatment variations (LUCAEUROPE) in Europe and the USA highlighting variations
An International Registry Study of Early-Stage NSCLC treatment variations (LUCAEUROPE) in Europe and the USA highlighting variations Open
View article: Direct aortic cannulation, a safe alternative to femoral artery cannulation - 17 years of type A dissection surgery experience
Direct aortic cannulation, a safe alternative to femoral artery cannulation - 17 years of type A dissection surgery experience Open
Aim: Optimal cannulation strategy for acute type A aortic dissection (ATAAD) surgery remains debated. Recent guidelines have advocated antegrade systemic perfusion through right axillary artery (RAX) cannulation, instead of femoral artery …
View article: The ESTS-AIR database—initial results of a multi-institutional database on airway surgery
The ESTS-AIR database—initial results of a multi-institutional database on airway surgery Open
OBJECTIVES Compared to lung resections, airway procedures are relatively rare in thoracic surgery. Despite this, a growing number of dedicated airway centres have formed throughout Europe. These centres are characterized by a close interdi…
View article: Asymptomatic esophageal perforation discovered after elective cardiac surgery: the importance of clinical awareness
Asymptomatic esophageal perforation discovered after elective cardiac surgery: the importance of clinical awareness Open
View article: Surviving the nonsurvivable combination of a mycotic aneurysm progressing into a concomitant aorto-bronchial- and aorto-esophageal fistula, a case report
Surviving the nonsurvivable combination of a mycotic aneurysm progressing into a concomitant aorto-bronchial- and aorto-esophageal fistula, a case report Open
View article: Intrinsic pulmonary sealing, its mechanisms and impact on validity and translational value of lung sealant studies: a pooled analysis of animal studies
Intrinsic pulmonary sealing, its mechanisms and impact on validity and translational value of lung sealant studies: a pooled analysis of animal studies Open
BACKGROUND: No validated and standardized animal models of pulmonary air leakage (PAL) exist for testing aerostatic efficacy of lung sealants. Lack of negative control groups in published studies and intrinsic sealing mechanisms of healthy…
View article: Sealing effectiveness of a novel NHS-POx based patch: experiments in a dynamic ex vivo porcine lung
Sealing effectiveness of a novel NHS-POx based patch: experiments in a dynamic ex vivo porcine lung Open
The novel NHS-POx patch shows promise as a lung sealant, demonstrating elevated BP, good adhesive strength and a superior AL-reduction.
View article: Endosonography With or Without Confirmatory Mediastinoscopy for Resectable Lung Cancer: A Randomized Clinical Trial
Endosonography With or Without Confirmatory Mediastinoscopy for Resectable Lung Cancer: A Randomized Clinical Trial Open
PURPOSE Resectable non–small-cell lung cancer (NSCLC) with a high probability of mediastinal nodal involvement requires mediastinal staging by endosonography and, in the absence of nodal metastases, confirmatory mediastinoscopy according t…
View article: Variations in current clinical practice of postoperative pericardial effusion: a questionnaire study
Variations in current clinical practice of postoperative pericardial effusion: a questionnaire study Open
Objective Postoperative pericardial effusion (PPE) occurs frequently after cardiac surgery, potentially leading to life-threatening cardiac tamponade. Specific treatment guidelines are currently lacking, possibly leading to variations in c…
View article: Ex-vivo exploration of an endobronchial sentinel lymph node procedure in lung cancer for optimizing workflow and evaluating feasibility of novel imaging tools
Ex-vivo exploration of an endobronchial sentinel lymph node procedure in lung cancer for optimizing workflow and evaluating feasibility of novel imaging tools Open
A navigation bronchoscopy mediated SLN procedure seems technically feasible. The Pioneer Plus is a suitable catheter to place tracer depots at multiple intra-/peri-tumoral sites, while receiving real-time feedback on the needle localizatio…
View article: Acute pain management after thoracoscopic lung resection: a systematic review and explorative meta-analysis
Acute pain management after thoracoscopic lung resection: a systematic review and explorative meta-analysis Open
OBJECTIVES Pain after thoracoscopic surgery may increase the incidence of postoperative complications and impair recovery. Guidelines lack consensus regarding postoperative analgesia. We performed a systematic review and meta-analysis to d…
View article: Upfront Resection of Locally-Advanced And/Or Cavitating Nsclc Followed by Chemoradiotherapy (and Adjuvant Systemic Treatment); Phase 1 Multicenter Study to Assess Treatment Feasibility and Safety (NVALT32/UPLAN-I Trial)
Upfront Resection of Locally-Advanced And/Or Cavitating Nsclc Followed by Chemoradiotherapy (and Adjuvant Systemic Treatment); Phase 1 Multicenter Study to Assess Treatment Feasibility and Safety (NVALT32/UPLAN-I Trial) Open
View article: Scaffold-based tissue engineering: Supercritical carbon dioxide as an alternative method for decellularization and sterilization of dense materials
Scaffold-based tissue engineering: Supercritical carbon dioxide as an alternative method for decellularization and sterilization of dense materials Open
Development of ready-to-use biomaterials and scaffolds is vital for further advancement of scaffold-based tissue engineering in clinical practice. Scaffolds need to mimic 3D ultrastructure, have adequate mechanical strength, are biocompati…
View article: Decision Making during the Learning Curve of Minimally Invasive Mitral Valve Surgery: A Focused Review for the Starting Minimally Invasive Surgeon
Decision Making during the Learning Curve of Minimally Invasive Mitral Valve Surgery: A Focused Review for the Starting Minimally Invasive Surgeon Open
Minimally invasive mitral valve surgery is evolving rapidly since the early 1990’s and is now increasingly adopted as the standard approach for mitral valve surgery. It has a long and challenging learning curve and there are many considera…
View article: Exploring variations in current clinical practice regarding postoperative pericardial effusion: a questionnaire study
Exploring variations in current clinical practice regarding postoperative pericardial effusion: a questionnaire study Open
Background Postoperative pericardial effusion (PPE) is a frequently occurring event after cardiac surgery, potentially leading to life-threatening cardiac tamponade. Unfortunately, no guidelines are currently available on this subject, pos…
View article: Optimal postoperative pain management after VATS lung resection by thoracic epidural analgesia, continuous paravertebral block or single-shot intercostal nerve block (OPtriAL): study protocol of a three-arm multicentre randomised controlled trial
Optimal postoperative pain management after VATS lung resection by thoracic epidural analgesia, continuous paravertebral block or single-shot intercostal nerve block (OPtriAL): study protocol of a three-arm multicentre randomised controlled trial Open
View article: OA06.05 Impact of COVID-19 Pandemic on Proportion and Treatment Patterns for Stage I Non-small Cell Lung Cancer in the Netherlands
OA06.05 Impact of COVID-19 Pandemic on Proportion and Treatment Patterns for Stage I Non-small Cell Lung Cancer in the Netherlands Open
View article: Correction: Long‑term follow‑up of voice changes after cervical mediastinoscopy
Correction: Long‑term follow‑up of voice changes after cervical mediastinoscopy Open
View article: Animal models of pulmonary parenchymal air leakage in the investigation of lung sealing devices: a systematic review protocol
Animal models of pulmonary parenchymal air leakage in the investigation of lung sealing devices: a systematic review protocol Open
Review question / Objective: 1.What are the methodological characteristics (animal model, disease model, sealants used, experimental groups, outcome measures) of previous in-vivo models used for the testing of lung sealing devices for the …