Adam C. Yu
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View article: Medical Therapies for Pediatric Lymphatic Malformations: A Systematic Review
Medical Therapies for Pediatric Lymphatic Malformations: A Systematic Review Open
Introduction: Lymphatic malformations (LM) are vascular anomalies that can be challenging to manage with new medical therapies emerging. This systematic review examines current medical therapies for pediatric patients with LMs that involve…
View article: Clinical Features and Current Therapeutic Approaches to Monilethrix: A Systematic Review
Clinical Features and Current Therapeutic Approaches to Monilethrix: A Systematic Review Open
Monilethrix is a rare congenital hair disorder characterized by fragile, beaded hair shafts due to mutations in various keratin or desmoglein 4 genes. A systematic review of 24 studies (16 pediatric only, 3 mixed adult and pediatric, 3 adu…
View article: Metagenomic Analysis Reveals Large‐Scale Disruptions of the Gut Microbiome in Parkinson's Disease
Metagenomic Analysis Reveals Large‐Scale Disruptions of the Gut Microbiome in Parkinson's Disease Open
Background Parkinson's disease (PD) has been consistently linked to alterations within the gut microbiome. Objective Our goal was to identify microbial features associated with PD incidence and progression. Methods Metagenomic sequencing w…
View article: Lucio’s phenomenon in a non-endemic region: A case report
Lucio’s phenomenon in a non-endemic region: A case report Open
Leprosy remains a persistent health challenge in endemic regions with cases rising in non-endemic regions such as North America. Patients with leprosy present with a variety of symptoms including limited skin lesions in tuberculoid leprosy…
View article: Two cases of childhood linear immunoglobulin A bullous dermatosis following multivisceral transplant: A case report
Two cases of childhood linear immunoglobulin A bullous dermatosis following multivisceral transplant: A case report Open
Childhood linear immunoglobulin A bullous dermatosis is a well-recognized autoimmune blistering dermatosis that can be idiopathic, drug-induced, secondary to autoimmune diseases, malignancies, infections, or gastrointestinal diseases inclu…
View article: Data-Driven Prediction of Fatigue in Parkinson’s Disease Patients
Data-Driven Prediction of Fatigue in Parkinson’s Disease Patients Open
Introduction: Numerous non-motor symptoms are associated with Parkinson’s disease (PD) including fatigue. The challenge in the clinic is to detect relevant non-motor symptoms while keeping patient-burden of questionnaires low and to take p…
View article: <scp>MIND</scp> and Mediterranean Diets Associated with Later Onset of Parkinson's Disease
<span>MIND</span> and Mediterranean Diets Associated with Later Onset of Parkinson's Disease Open
Background The MIND diet has been linked with prevention of Alzheimer's disease and cognitive decline but has not been fully assessed in the context of Parkinson's disease (PD). The objective of the present study was to determine whether M…
View article: Reply to: ‘Comment on “Microbiota Composition and Metabolism Are Associated With Gut Function in Parkinson’s Disease”’
Reply to: ‘Comment on “Microbiota Composition and Metabolism Are Associated With Gut Function in Parkinson’s Disease”’ Open
We thank Dr. Zhang for his interest in our study1 and for the valuable feedback.2 Dr. Zhang correctly remarks that individuals in the same household typically share similar diets, highlighting our decision to enroll patient spouses as cont…
View article: Response to Issues Paper on Human Rights and Technology
Response to Issues Paper on Human Rights and Technology Open
View article: Neuroinflammatory conditions modulate ARNT2 and RME-8 expression within the CNS
Neuroinflammatory conditions modulate ARNT2 and RME-8 expression within the CNS Open
Microglia are the primary immune cells found within the central nervous system (CNS), playing a vital role in neuronal function, trophic support and also modulating immune or inflammatory responses to pathogens or damage during disease. Mi…