Adam Swensen
YOU?
Author Swipe
View article: Corrigendum to “Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation” [Mol Metab 18 (2018) 153–163]
Corrigendum to “Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation” [Mol Metab 18 (2018) 153–163] Open
View article: Increased inflammation as well as decreased endoplasmic reticulum stress and translation differentiate pancreatic islets from donors with pre-symptomatic stage 1 type 1 diabetes and non-diabetic donors
Increased inflammation as well as decreased endoplasmic reticulum stress and translation differentiate pancreatic islets from donors with pre-symptomatic stage 1 type 1 diabetes and non-diabetic donors Open
The LC-MS raw datasets that support the findings of this study have been deposited in the online repository: MassIVE ( https://massive.ucsd.edu/ProteoSAFe/static/massive.jsp ) with accession no. MSV000090212.
View article: A multiplex assay of leptin, resistin, and adiponectin by immunoaffinity enrichment and targeted mass spectrometry
A multiplex assay of leptin, resistin, and adiponectin by immunoaffinity enrichment and targeted mass spectrometry Open
A multi-IA-LC-MS/MS assay was developed for the simultaneous and sensitive measurement of leptin, resistin, and adiponectin in clinical samples. This quantitative method shows significant potential for applications related to obesity and c…
View article: Increased Inflammation as well as Decreased Endoplasmic Reticulum Stress and Translation Differentiate Pancreatic Islets of Pre-symptomatic Stage 1 Type 1 Diabetes and Non-diabetic Cases
Increased Inflammation as well as Decreased Endoplasmic Reticulum Stress and Translation Differentiate Pancreatic Islets of Pre-symptomatic Stage 1 Type 1 Diabetes and Non-diabetic Cases Open
Aims/hypothesis Progression to type 1 diabetes (T1D) is associated with genetic factors, the presence of autoantibodies, and a decline in β cell insulin secretion in response to glucose. Very little is known regarding the molecular changes…
View article: Exploring new frontiers in type 1 diabetes through advanced mass-spectrometry-based molecular measurements
Exploring new frontiers in type 1 diabetes through advanced mass-spectrometry-based molecular measurements Open
View article: Data for EMSL Project 48705 from February 2022
Data for EMSL Project 48705 from February 2022 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Multiplexed quantitative proteomics in prostate cancer biomarker development
Multiplexed quantitative proteomics in prostate cancer biomarker development Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from March 2024
Data for EMSL Project 51514 from March 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Data for EMSL Project 51514 from April 2024
Data for EMSL Project 51514 from April 2024 Open
View article: Top-Down Proteomics of Mouse Islets With Beta Cell CPE Deletion Reveals Molecular Details in Prohormone Processing
Top-Down Proteomics of Mouse Islets With Beta Cell CPE Deletion Reveals Molecular Details in Prohormone Processing Open
Altered prohormone processing, such as with proinsulin and pro-islet amyloid polypeptide (proIAPP), has been reported as an important feature of prediabetes and diabetes. Proinsulin processing includes removal of several C-terminal basic a…
View article: <strong>Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice</strong>
<strong>Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice</strong> Open
Carboxypeptidase E (CPE) facilitates the conversion of prohormones into mature hormones and is highly expressed in multiple neuroendocrine tissues. Carriers of CPE mutations have elevated plasma proinsulin and develop severe obesi…
View article: <strong>Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice</strong>
<strong>Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice</strong> Open
Carboxypeptidase E (CPE) facilitates the conversion of prohormones into mature hormones and is highly expressed in multiple neuroendocrine tissues. Carriers of CPE mutations have elevated plasma proinsulin and develop severe obesi…
View article: Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice
Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice Open
Carboxypeptidase E (CPE) facilitates the conversion of prohormones into mature hormones and is highly expressed in multiple neuroendocrine tissues. Carriers of CPE mutations have elevated plasma proinsulin and develop severe obesity and hy…
View article: Proteome Mapping of the Human Pancreatic Islet Microenvironment Reveals Endocrine–Exocrine Signaling Sphere of Influence
Proteome Mapping of the Human Pancreatic Islet Microenvironment Reveals Endocrine–Exocrine Signaling Sphere of Influence Open
View article: Predicting chronic postsurgical pain: current evidence and a novel program to develop predictive biomarker signatures
Predicting chronic postsurgical pain: current evidence and a novel program to develop predictive biomarker signatures Open
Chronic pain affects more than 50 million Americans. Treatments remain inadequate, in large part, because the pathophysiological mechanisms underlying the development of chronic pain remain poorly understood. Pain biomarkers could potentia…