Explanipedia

Evolution of the Artificial Pancreas: Components and Integration—CGMs, Insulin, and AP Systems Open

Richard M. Bergenstal, Adam Heller, Marc D. Breton, Robert A. Vigersky, Susan A. Brown , et al. · 2025

The landmark Diabetes Control and Complications Trial (DCCT) showed that glucose control is critical to reducing the risk of diabetes-related complications. This chapter outlines a series of innovations and investigations that followed the…

Non-invasive, continuous oral delivery of solid levodopa-carbidopa for management of Parkinson’s disease Open

William L. Murch, John Spiridigliozzi, Adam Heller, Ephraim Heller · 2024

When short plasma half-life drugs act only briefly, they require frequent or continuous administration. We report the engineering of a non-invasive oral drug delivery system for long-term, continuous administration of these drugs. Their no…

Frontispiz: Stainless Steel‐Like Passivation Inspires Persistent Silicon Anodes for Lithium‐Ion Batteries Open

Jie Lin, Laisen Wang, Qingshui Xie, Qing Luo, Dong‐Liang Peng , et al. · 2023

Batteries. In their Research Article (e202216557), Jie Lin, Dong-Liang Peng, C. Buddie Mullins, Adam Heller et al. report the development of three-dimensional bulk-passivated and surface-coated silicon films to mitigate volume expansion of…

Frontispiece: Stainless Steel‐Like Passivation Inspires Persistent Silicon Anodes for Lithium‐Ion Batteries Open

Jie Lin, Laisen Wang, Qingshui Xie, Qing Luo, Dong‐Liang Peng , et al. · 2023

Batteries. In their Research Article (e202216557), Jie Lin, Dong-Liang Peng, C. Buddie Mullins, Adam Heller et al. report the development of three-dimensional bulk-passivated and surface-coated silicon films to mitigate volume expansion of…

Transition metal-doped Ni-rich layered cathode materials for durable Li-ion batteries Open

H. Hohyun Sun, Un‐Hyuck Kim, Jeonghyeon Park, Sang-Wook Park, Dong‐Hwa Seo , et al. · 2021

Telestroke: Maintaining Quality Acute Stroke Care During the COVID-19 Pandemic Open

Theresa Sevilis, Mark McDonald, Amanda Avila, Gregory W. Heath, Lan Gao , et al. · 2021

Introduction: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted acute stroke care globally. Decreased stroke presentations and concern for delays in acute stroke care have been identified. This study evalua…

Detlev Müller’s Discovery of Glucose Oxidase in 1925 Open

Adam Heller, Jens Ulstrup · 2021

ADVERTISEMENT RETURN TO ISSUEPREVCommentNEXTDetlev Müller's Discovery of Glucose Oxidase in 1925Adam Heller*Adam HellerUniversity of Texas, Austin, Texas 78712, United States*Email: [email protected]More by Adam Hellerhttp://orcid.org/0000…

Intellectual‐Integrity in Government‐Funded Research Open

Adam Heller · 2020

Ehud Keinan's invitation to write for Rosarium Philosophorum has given me an opportunity to alert colleagues to drivers of government-funded, media-driven, non-innovative research. It is a managed, development-like activity, performed by l…

Potentially Pathogenic Calcium Oxalate Dihydrate and Titanium Dioxide Crystals in the Alzheimer’s Disease Entorhinal Cortex Open

Adam Heller, Sheryl S. Coffman, Karalee Jarvis · 2020

Knowing that Alzheimer’s disease (AD) nucleates in the entorhinal cortex (EC), samples of 12 EC specimens were probed for crystals by a protocol detecting fewer than 1/5000th of those present. Of the 61 crystals found, 31 were expected and…

Beyond Doping and Coating: Prospective Strategies for Stable High-Capacity Layered Ni-Rich Cathodes Open

H. Hohyun Sun, Hoon‐Hee Ryu, Un‐Hyuck Kim, Jason A. Weeks, Adam Heller , et al. · 2020

This Perspective discusses the prospective strategies for overcoming the stability and capacity trade-off associated with increased Ni content in layered Ni-rich Li[NixCoyMnz]O2 (NCM) and Li[NixCoyAlz]O2 (NCA) cathodes. The Ni-rich NCM and…

Electrode Degradation in Lithium-Ion Batteries Open

Joshua P. Pender, Gaurav Jha, Duck Hyun Youn, Joshua Ziegler, Ilektra Andoni , et al. · 2020

Although Li-ion batteries have emerged as the battery of choice for electric vehicles and large-scale smart grids, significant research efforts are devoted to identifying materials that offer higher energy density, longer cycle life, lower…

Sulfur‐Rich Molybdenum Sulfide as an Anode Coating to Improve Performance of Lithium Metal Batteries Open

Melissa Meyerson, Anish H. Pandit, Jason A. Weeks, Oluwaniyi Mabayoje, Hugo Celio , et al. · 2019

In lithium metal batteries (LMBs), the reaction between metallic Li and organic electrolytes consumes both Li and electrolyte, while the inhomogeneity of the resulting solid‐electrolyte interphase (SEI) contributes to inhomogeneous Li depo…

Submicron Crystals of the Parkinson’s Disease Substantia nigra: Calcium Oxalate, Titanium Dioxide and Iron Oxide Open

Adam Heller, Sheryl S. Coffman · 2019

Parkinson’s disease (PD) results of the death of dopaminergic neurons of the substantia nigra. When activated, the NLRP3 inflammasome of phagocytes releases inflammatory agents, their release resulting in the death of proximal cells. The h…

Controlled Prelithiation of PbS to Pb/Li2S for High Initial Coulombic Efficiency in Lithium Ion Batteries Open

Alan Guo, Eric Chen, Adam Heller, C. Buddie Mullins · 2019

PbS nanoparticle aggregates were synthesized in a simple aqueous reaction at room temperature, and were tested as a lithium ion anode material, with a gravimetric capacity of 374 mAh/g at C/2, and a 0.15% capacity loss per cycle. However, …

Simple Microwave‐Assisted Synthesis of Delafossite CuFeO2 as an Anode Material for Sodium‐Ion Batteries Open

Duck Hyun Youn, Yo Han Choi, Jun‐Hyuk Kim, Sungmin Han, Adam Heller , et al. · 2018

A simple synthesis of microcrystalline delafossite CuFeO 2 is reported. Rhombohedral CuFeO 2 0.7–2.5 μm crystals were obtained by heating an aqueous solution of Fe(NO 3 ) 3 , Cu(NO 3 ) 2 , and propionaldehyde to 180 °C for 2 h in a microwa…

Association of Type 2 Diabetes with Submicron Titanium Dioxide Crystals in the Pancreas Open

Adam Heller, Karalee Jarvis, Sheryl S. Coffman · 2018

Pigment-grade titanium dioxide (TiO₂) of 200-300 nm particle diameter is the most widely used submicron-sized particle material. Inhaled and ingested TiO₂ particles enter the bloodstream, are phagocytized by macrophag…

Integration of PV Modules in Energy Yield Optimized Carbon Concrete Composite Facades Open

Jens Schneider, L. Dämmig, Christian Rudolf, M. Gorges, Adam Heller , et al. · 2016

Carbon reinforcement of concrete façades allows for lighter weight and more flexible shapes in modern buildings. The German C3 (carbon concrete composite) project aims at developing this technology further. Part of the project is integrati…

Communication—Stages in the Dynamic Electrochemical Lithiation of Lead Open

Sean M. Wood, Codey H. Pham, Adam Heller, C. Buddie Mullins · 2016

The intermediates and final phase in the dynamic electrochemical lithiation of lead at ambient temperature were determined by ex situ XRD. The phases and their corresponding potentials matched well with coulometric data. The detected phase…

A Simple Synthesis of an N‐Doped Carbon ORR Catalyst: Hierarchical Micro/Meso/Macro Porosity and Graphitic Shells Open

David Eisenberg, Wowa Stroek, Norbert J. Geels, C.S. Sandu, Adam Heller , et al. · 2015

Replacing platinum as an oxygen reduction catalyst is an important scientific and technological challenge. Herein we report a simple synthesis of a complex carbon with very good oxygen reduction reaction (ORR) activity at pH 13. Pyrolysis …

Lithiation and Delithiation of Lead Sulfide (PbS) Open

Sean M. Wood, Emily Powell, Adam Heller, C. Buddie Mullins · 2015

The lithiation and delithiation of PbS was studied. Below 1.0 V vs. Li/Li+, lithiation produced a series of Li-Pb alloys and Li2S. The Li-Pb alloys were reversibly lithiated and delithiated, but at a 1 C rate their capacity faded through 1…

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