Xiaodong Zhang
YOU?
Author Swipe
View article: STCNet: a hybrid Transformer and CNN network for surface defect detection of steel continuous casting billets
STCNet: a hybrid Transformer and CNN network for surface defect detection of steel continuous casting billets Open
In steel manufacturing, steel continuous casting billets are essential intermediate products, making surface defect detection (SDD) a critical task. To address the challenge of limited industrial datasets that hinder the accuracy of deep l…
View article: Amyotrophic Lateral Sclerosis as a Multistep Process in the United States: A Population‐Based Study
Amyotrophic Lateral Sclerosis as a Multistep Process in the United States: A Population‐Based Study Open
Background Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease that typically results in death within 3–5 years from symptom onset. However, little is known about the environmental exposures, clinical aspe…
View article: Metal-Induced Genotoxic Events: Possible Distinction Between Sporadic and Familial ALS
Metal-Induced Genotoxic Events: Possible Distinction Between Sporadic and Familial ALS Open
Metal exposure is a potential risk factor for amyotrophic lateral sclerosis (ALS). Increasing evidence suggests that elevated levels of DNA damage are present in both familial (fALS) and sporadic (sALS) forms of ALS, characterized by the s…
View article: Incidence of ALS in all 50 states in the United States, data from the National ALS Registry, 2012–2019
Incidence of ALS in all 50 states in the United States, data from the National ALS Registry, 2012–2019 Open
These findings summarize the incidence of ALS for all 50 states from 2012 to 2019. This is a continuing effort to identify ALS cases nationally. The establishment of the Registry allows for epidemiological analyses of ALS data and the asse…
View article: Amyotrophic lateral sclerosis estimated prevalence cases from 2022 to 2030, data from the national ALS Registry
Amyotrophic lateral sclerosis estimated prevalence cases from 2022 to 2030, data from the national ALS Registry Open
Objective: To estimate the projected number of ALS cases in the United States from 2022 to 2030. Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neuromuscular disease with no known cure. Because ALS is not a notifiabl…
View article: Retinectomy under air
Retinectomy under air Open
View article: Correction to: Comparison of Demographics: National Amyotrophic Lateral Sclerosis Registry and Clinical Trials Data
Correction to: Comparison of Demographics: National Amyotrophic Lateral Sclerosis Registry and Clinical Trials Data Open
View article: Comparison of Demographics: National Amyotrophic Lateral Sclerosis Registry and Clinical Trials Data
Comparison of Demographics: National Amyotrophic Lateral Sclerosis Registry and Clinical Trials Data Open
View article: Prevalence of ALS in all 50 states in the United States, data from the National ALS Registry, 2011–2018
Prevalence of ALS in all 50 states in the United States, data from the National ALS Registry, 2011–2018 Open
Objective: To summarize the prevalence of ALS in all 50 states and Washington, DC in the United States from 2011 to 2018 using data collected and analyzed by the National ALS Registry. In October 2010, the federal Agency for Toxic S…
View article: Implementation of optical coherence tomography in retinopathy of prematurity screening
Implementation of optical coherence tomography in retinopathy of prematurity screening Open
Purpose of review In this review, we explore the investigational applications of optical coherence tomography (OCT) in retinopathy of prematurity (ROP), the insights they have delivered thus far, and key milestones for its integration into…
View article: A microRNA diagnostic biomarker for amyotrophic lateral sclerosis
A microRNA diagnostic biomarker for amyotrophic lateral sclerosis Open
Blood-based diagnostic biomarkers for amyotrophic lateral sclerosis will improve patient outcomes and positively impact novel drug development. Critical to the development of such biomarkers is robust method validation, optimization and re…
View article: Prevalence of amyotrophic lateral sclerosis in the United States, 2018
Prevalence of amyotrophic lateral sclerosis in the United States, 2018 Open
Consistent with previous estimates that used CRC, ALS prevalence in the United States is about 29,824 cases per year.
View article: Assessing the Impact of Image Quality on Deep Learning Classification of Infectious Keratitis
Assessing the Impact of Image Quality on Deep Learning Classification of Infectious Keratitis Open
Proprietary or commercial disclosure may be found after the references.
View article: Polyglucosan body disease in an aged chimpanzee (<i>Pan troglodytes</i>)
Polyglucosan body disease in an aged chimpanzee (<i>Pan troglodytes</i>) Open
A 57‐year‐old female chimpanzee presented with a brief history of increasing lethargy and rapidly progressive lower‐limb weakness that culminated in loss of use. Postmortem examination revealed no significant gross lesions in the nervous s…
View article: Data from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells
Data from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells Open
The ability of nanoparticles to target tumors and to enable site-specific drug release provides a unique system for the delivery of effective therapy with reduced toxic side effects. In this study, we used mesoporous silica nanoparticles (…
View article: Supplementary Materials and Methods from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells
Supplementary Materials and Methods from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells Open
Supplementary Materials and Methods
View article: Supplemental Figures 1 through 14 from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells
Supplemental Figures 1 through 14 from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells Open
Adsorption/desorption isotherms and pore size distributions of MSN-NH2 (S1). FITR spectra of MSN-NH2 and MSN-destriobiotin (S2). DLS and TEM characterizations of MSN-HA/Dox (S3). Figures of MSN-HA loaded with rhodamine B (S4). Release prof…
View article: Data from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells
Data from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells Open
The ability of nanoparticles to target tumors and to enable site-specific drug release provides a unique system for the delivery of effective therapy with reduced toxic side effects. In this study, we used mesoporous silica nanoparticles (…
View article: Supplementary Materials and Methods from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells
Supplementary Materials and Methods from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells Open
Supplementary Materials and Methods
View article: Supplemental Figures 1 through 14 from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells
Supplemental Figures 1 through 14 from A Hyaluronidase-Responsive Nanoparticle-Based Drug Delivery System for Targeting Colon Cancer Cells Open
Adsorption/desorption isotherms and pore size distributions of MSN-NH2 (S1). FITR spectra of MSN-NH2 and MSN-destriobiotin (S2). DLS and TEM characterizations of MSN-HA/Dox (S3). Figures of MSN-HA loaded with rhodamine B (S4). Release prof…
View article: Impact of the National Amyotrophic Lateral Sclerosis Registry: Analysis of Registry‐funded Research
Impact of the National Amyotrophic Lateral Sclerosis Registry: Analysis of Registry‐funded Research Open
Objective This research aims to examine the impact of the National Amyotrophic Lateral Sclerosis (ALS) Registry‐funded research activities. Methods Registry‐funded research and related publications were identified through the National ALS …
View article: A revision to the United States national ALS registry’s algorithm to improve Case-Ascertainment
A revision to the United States national ALS registry’s algorithm to improve Case-Ascertainment Open
The Registry's existing algorithm likely results in the under-ascertainment of ALS cases. However, updating the algorithm with the inclusion of patients having been prescribed ALS-specific drugs, even with a single prescription, leads to i…
View article: Examination of Food Consumption and Prevalence of Inflammatory Bowel Disease in US Adult Population: Analysis of National Health Interview Survey 2015
Examination of Food Consumption and Prevalence of Inflammatory Bowel Disease in US Adult Population: Analysis of National Health Interview Survey 2015 Open
BACKGROUND: Ulcerative colitis and Crohn’s disease are the two most common forms of inflammatory bowel disease (IBD). It is a chronic inflammatory condition of the gastrointestinal tract. Consumption of diets that are high in fat, sugars, …
View article: Prevalence of amyotrophic lateral sclerosis in the United States using established and novel methodologies, 2017
Prevalence of amyotrophic lateral sclerosis in the United States using established and novel methodologies, 2017 Open
Objective:To estimate the prevalence of amyotrophic lateral sclerosis (ALS) in the United States for 2017 using data from the National ALS Registry (Registry) as well as capture-recapture methodology to account for under-ascertainme…
View article: The Role of CD98 in Dysregulation of MiRNA and Protein Expression Along the Villus-Crypt Axis in Intestinal Epithelium
The Role of CD98 in Dysregulation of MiRNA and Protein Expression Along the Villus-Crypt Axis in Intestinal Epithelium Open
IEC-specific overexpression of CD98 mediates intestinal inflammation and intestinal epithelial barrier dysfunction in experimental colitis and increase the susceptibility to colitis-asociated cancer. Here we demonstrated homeostatic gene p…
View article: Federated Learning for Multicenter Collaboration in Ophthalmology
Federated Learning for Multicenter Collaboration in Ophthalmology Open
View article: Federated Learning for Multicenter Collaboration in Ophthalmology
Federated Learning for Multicenter Collaboration in Ophthalmology Open
View article: Improved Training Efficiency for Retinopathy of Prematurity Deep Learning Models Using Comparison versus Class Labels
Improved Training Efficiency for Retinopathy of Prematurity Deep Learning Models Using Comparison versus Class Labels Open
View article: Prevalence of persistent avascular retina in untreated children with a history of retinopathy of prematurity screening
Prevalence of persistent avascular retina in untreated children with a history of retinopathy of prematurity screening Open
View article: Recruitment of Patients With Amyotrophic Lateral Sclerosis for Clinical Trials and Epidemiological Studies: Descriptive Study of the National ALS Registry’s Research Notification Mechanism
Recruitment of Patients With Amyotrophic Lateral Sclerosis for Clinical Trials and Epidemiological Studies: Descriptive Study of the National ALS Registry’s Research Notification Mechanism Open
Background Researchers face challenges in patient recruitment, especially for rare, fatal diseases such as amyotrophic lateral sclerosis (ALS). These challenges include obtaining sufficient statistical power as well as meeting eligibility …