Adam Morton
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View article: The Impact of Pregnancy on Functional Neurological Disorder ( <scp>FND</scp> )
The Impact of Pregnancy on Functional Neurological Disorder ( <span>FND</span> ) Open
Background Functional neurological disorder (FND) commonly affects women of reproductive age, yet little is known about its interaction with pregnancy and childbirth. We aimed to explore FND symptom changes during pregnancy, delivery and t…
View article: The Management of Parkinson's Disease Before, during and after Pregnancy—an <scp>MDS</scp> Scientific Issues Committee Review
The Management of Parkinson's Disease Before, during and after Pregnancy—an <span>MDS</span> Scientific Issues Committee Review Open
Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postp…
View article: <i>CYP24A1</i> loss-of-function mutation as a rare cause of parathyroid (PTH)-independent severe hypercalcaemia in pregnancy
<i>CYP24A1</i> loss-of-function mutation as a rare cause of parathyroid (PTH)-independent severe hypercalcaemia in pregnancy Open
View article: Inherited aortopathies and risk of aortic dissection and aortic syndrome in pregnancy
Inherited aortopathies and risk of aortic dissection and aortic syndrome in pregnancy Open
Acute aortic dissection related to pregnancy is rare, however represented the third most common cause of pregnancy-related cardiovascular death in the 2017 UK-MBBRACE report. The majority of women with pregnancy-related aortic dissection h…
View article: Magnesium deficiency and dilated cardiomyopathy diagnosed peripartum
Magnesium deficiency and dilated cardiomyopathy diagnosed peripartum Open
Dilated cardiomyopathy in pregnancy, whether diagnosed pre-conception, or occurring de novo during pregnancy, may be associated with significant maternal morbidity and mortality. Hypomagnesaemia is associated with ventricular arrhythmias a…
View article: Benign Symptomatic Thyroid Nodules—A Place for a Randomised Trial of Sham Procedure Versus Radiofrequency Ablation?
Benign Symptomatic Thyroid Nodules—A Place for a Randomised Trial of Sham Procedure Versus Radiofrequency Ablation? Open
View article: Visual loss during pregnancy due to physiological pituitary hyperplasia
Visual loss during pregnancy due to physiological pituitary hyperplasia Open
Physiological pituitary hyperplasia is due to adenohypophyseal cell number increase and is characterised by diffuse isodense pituitary enlargement beyond age-appropriate sizes. It most commonly occurs in females undergoing reproductive cha…
View article: Ketotic Hypoglycaemia Following Sleeve Gastrectomy
Ketotic Hypoglycaemia Following Sleeve Gastrectomy Open
Post‐bariatric surgery hypoglycaemia is typically mediated by hyperinsulinaemia, although the exact mechanisms are incompletely understood. Two cases of non‐insulin mediated, ketotic hypoglycaemia following sleeve gastrectomy are presented…
View article: Letter to the Editor re: Paz-Ilbarra C-ZM et al. A giant parathyroid cyst causing primary hyperparathyroidism in a pregnant woman: Case report and literature review.
Letter to the Editor re: Paz-Ilbarra C-ZM et al. A giant parathyroid cyst causing primary hyperparathyroidism in a pregnant woman: Case report and literature review. Open
View article: The risk of recurrence of acute fatty liver of pregnancy – a review of the current literature
The risk of recurrence of acute fatty liver of pregnancy – a review of the current literature Open
Acute fatty liver of pregnancy is associated with significant maternal and fetal morbidity and mortality. Defects in fatty acid metabolism appear to play a role in pathogenesis, and several pathogenic variants leading to enzyme deficiencie…
View article: Ptyalism gravidarum
Ptyalism gravidarum Open
Ptyalism gravidarum, or sialorrhoea, is a highly distressing maternal condition characterised by excess salivation and difficulty swallowing saliva, requiring the affected woman to frequently expectorate. The literature is sparse and somew…
View article: Letter to the Editor: Mineralocorticoid receptor antagonists in adults with resistant hypertension and obstructive sleep apnoea
Letter to the Editor: Mineralocorticoid receptor antagonists in adults with resistant hypertension and obstructive sleep apnoea Open
View article: Letter to the Editor: Additional preconception considerations for patients with diabetes
Letter to the Editor: Additional preconception considerations for patients with diabetes Open
View article: Probable acute fatty liver of pregnancy presenting with dyspnoea and ground-glass opacities
Probable acute fatty liver of pregnancy presenting with dyspnoea and ground-glass opacities Open
We present the case of a postpartum woman presenting with acute dyspnoea and hypoxia. She was found to have liver enzyme derangement with evidence of synthetic dysfunction. Computed tomography of her chest showed ground-glass opacities. Th…
View article: A case of hyponatraemia cured by delivery
A case of hyponatraemia cured by delivery Open
Hyponatraemia is the most common electrolyte abnormality in pregnancy. In severe cases, it can result in significant maternal and fetal morbidity and mortality. The prevalence of hyponatraemia in pregnancy has been estimated to be 0.27%, w…
View article: Milk-alkali syndrome
Milk-alkali syndrome Open
A woman, aged 50 years, described experiencing abdominal pain and constipation for five months.Her blood tests showed hypercalcaemia and mild renal dysfunction.Serum calcium was 2.75 mmol/L (reference range [RR] 2.1-2.6 mmol/L), serum crea…
View article: Transient osteoporosis of the hip in pregnancy
Transient osteoporosis of the hip in pregnancy Open
Transient osteoporosis of the hip is an uncommon bone marrow oedema syndrome of unknown pathophysiology affecting previously healthy pregnant women and young to middle-aged men. The disorder is characterised by hip pain, reduced mobility, …
View article: Markedly elevated liver enzymes in pregnancy: A 10-year review of cases in a tertiary maternal hospital in Brisbane, Australia
Markedly elevated liver enzymes in pregnancy: A 10-year review of cases in a tertiary maternal hospital in Brisbane, Australia Open
Abnormalities of liver function are common during pregnancy. This retrospective study examined the incidence, aetiology and adequacy of investigation of pregnant women with markedly elevated aspartate aminotransferase and/or alanine transa…
View article: Glycogenic hepatopathy associated with hepatic steatosis in type 1 diabetes Short title: GH associated with MAFLD in T1DM
Glycogenic hepatopathy associated with hepatic steatosis in type 1 diabetes Short title: GH associated with MAFLD in T1DM Open
Purpose: Glycogenic hepatopathy is associated with significant psychosocial consequences and health costs. Metabolic Dysfunction-Associated Steatotic Liver Disease and glycogenic hepatopathy are frequently confused as “fatty liver” when se…
View article: Hypokalaemia in pregnancy – Prevalence, underlying causes, and an approach to investigation
Hypokalaemia in pregnancy – Prevalence, underlying causes, and an approach to investigation Open
Objective To investigate the prevalence and aetiology of hypokalaemia in pregnancy. Methods This was a five-year retrospective audit of women who received care at a tertiary hospital, who developed hypokalaemia during pregnancy and within …
View article: Investigating gastrointestinal disorders in pregnancy
Investigating gastrointestinal disorders in pregnancy Open
This article reviews anatomical and physiological changes and alterations in reference intervals for laboratory tests in healthy pregnancy, pertinent to investigation of the gastrointestinal system. The safety of procedures and radiologica…
View article: Response to: rare causes of abdominal pain: a primer for the admitting general surgeon
Response to: rare causes of abdominal pain: a primer for the admitting general surgeon Open
View article: Postpartum complications following neuraxial anaesthesia for obstetric physicians
Postpartum complications following neuraxial anaesthesia for obstetric physicians Open
Neuraxial analgesia and anaesthesia are widely accepted and well-tolerated modes of delivery analgesia, being employed in up to 76% of vaginal deliveries and 94% of caesarean deliveries in the United States. 1 A cause of considerable conce…
View article: Gordon's syndrome in pregnancy
Gordon's syndrome in pregnancy Open
Gordon's syndrome, also known as pseudohypoaldosteronism type II and familial hyperkalaemic hypertension, is a rare inherited condition characterised by familial hyperkalaemia, normal anion gap hyperchloraemic metabolic acidosis, low renin…
View article: Akathisia and oculogyric crisis in hyperemesis gravidarum
Akathisia and oculogyric crisis in hyperemesis gravidarum Open
Hyperemesis gravidarum complicates 0.5–2% of pregnancies. HG is associated with insomnia, significantly increased risks of anxiety and depression, and may be associated with feelings of guilt, social isolation and thoughts of suicidal idea…
View article: Severe hyponatraemia peripartum associated with omeprazole therapy
Severe hyponatraemia peripartum associated with omeprazole therapy Open
Hyponatraemia is the most commonly encountered electrolyte abnormality in pregnancy and may be associated with adverse maternal and neonatal outcomes. Rapid onset, severe hyponatraemia has been reported with proton-pump inhibitor therapy i…
View article: Pregnancy outcome with maternal <i>HNF1B</i> gene mutations and 17q12 deletions
Pregnancy outcome with maternal <i>HNF1B</i> gene mutations and 17q12 deletions Open
There is an increasing body of literature regarding monogenic diabetes, particularly the more common forms of glucokinase and HNF1-alpha mutations (MODY2 and MODY3). There is relatively little published literature regarding rarer mutations…
View article: Possible additional criteria for the diagnosis of preeclampsia with severe features
Possible additional criteria for the diagnosis of preeclampsia with severe features Open
Preeclampsia is a disorder affecting multiple organ systems. Preeclampsia with severe features may prompt consideration of delivery. The diagnostic criteria for preeclampsia with severe features, while focusing upon maternal cardiopulmonar…
View article: Herbal tea and hypoadrenalism
Herbal tea and hypoadrenalism Open
View article: Hyperventilation imitating preeclampsia
Hyperventilation imitating preeclampsia Open