Adam Pym
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View article: The P450s Cyp6cy3 and Cyp6cy4 Confer Resistance to Flupyradifurone in the Green Peach Aphid Myzus Persicae
The P450s Cyp6cy3 and Cyp6cy4 Confer Resistance to Flupyradifurone in the Green Peach Aphid Myzus Persicae Open
View article: Aberrant splicing of a nicotinic acetylcholine receptor alpha 6 subunit is associated with spinosad tolerance in the thrips predator Orius laevigatus
Aberrant splicing of a nicotinic acetylcholine receptor alpha 6 subunit is associated with spinosad tolerance in the thrips predator Orius laevigatus Open
Susceptibility to insecticides is one of the limiting factors preventing wider adoption of natural enemies to control insect pest populations. Identification and selective breeding of insecticide tolerant strains of commercially used biolo…
View article: Aberrant Splicing of a Nicotinic Acetylcholine Receptor Alpha 6 Subunit is Associated with Spinosad Tolerance in the Thrips Predator Orius Laevigatus
Aberrant Splicing of a Nicotinic Acetylcholine Receptor Alpha 6 Subunit is Associated with Spinosad Tolerance in the Thrips Predator Orius Laevigatus Open
View article: Differentially Spliced Mitochondrial Cyp419a1 Contributes to Ethiprole Resistance in Nilaparvata Lugens
Differentially Spliced Mitochondrial Cyp419a1 Contributes to Ethiprole Resistance in Nilaparvata Lugens Open
View article: The role of the Bemisia tabaci and Trialeurodes vaporariorum cytochrome-P450 clade CYP6DPx in resistance to nicotine and neonicotinoids
The role of the Bemisia tabaci and Trialeurodes vaporariorum cytochrome-P450 clade CYP6DPx in resistance to nicotine and neonicotinoids Open
The alkaloid, nicotine, produced by tobacco and other Solanaceae as an anti-herbivore defence chemical is one of the most toxic natural insecticides in nature. However, some insects, such as the whitefly species, Trialeurodes vaporariorum …
View article: A cytochrome P450 insecticide detoxification mechanism is not conserved across the Megachilidae family of bees
A cytochrome P450 insecticide detoxification mechanism is not conserved across the Megachilidae family of bees Open
Recent work has demonstrated that many bee species have specific cytochrome P450 enzymes (P450s) that can efficiently detoxify certain insecticides. The presence of these P450s, belonging or closely related to the CYP9Q subfamily (CYP9Q‐re…
View article: Transposon accumulation at xenobiotic gene family loci in aphids
Transposon accumulation at xenobiotic gene family loci in aphids Open
The evolution of resistance is a major challenge for the sustainable control of pests and pathogens. Thus, a deeper understanding of the evolutionary and genomic mechanisms underpinning resistance evolution is required to safeguard health …
View article: Overexpression of the UDP-glycosyltransferase UGT34A23 confers resistance to the diamide insecticide chlorantraniliprole in the tomato leafminer, Tuta absoluta
Overexpression of the UDP-glycosyltransferase UGT34A23 confers resistance to the diamide insecticide chlorantraniliprole in the tomato leafminer, Tuta absoluta Open
The tomato leafminer, Tuta absoluta, is an invasive crop pest that has evolved resistance to many of the insecticides used for its control. To facilitate the investigation of the underpinning mechanisms of resistance in this species we gen…
View article: A single point mutation in the Bemisia tabaci cytochrome-P450 CYP6CM1 causes enhanced resistance to neonicotinoids
A single point mutation in the Bemisia tabaci cytochrome-P450 CYP6CM1 causes enhanced resistance to neonicotinoids Open
The tobacco whitefly, Bemisia tabaci, is a polyphagous crop pest which causes high levels of economic damage across the globe. Insecticides are often required for the effective control of this species, among which the neonicotinoid class h…
View article: Transposon accumulation at xenobiotic gene family loci: a comparative genomic analysis in aphids
Transposon accumulation at xenobiotic gene family loci: a comparative genomic analysis in aphids Open
The evolution of resistance is a major challenge for the sustainable control of pests and pathogens. Thus, a deeper understanding of the evolutionary and genomic mechanisms underpinning resistance evolution is required to safeguard health …
View article: Spirotetramat resistance in <i>Myzus persicae</i> (Sulzer) (Hemiptera: Aphididae) and its association with the presence of the <scp>A2666V</scp> mutation
Spirotetramat resistance in <i>Myzus persicae</i> (Sulzer) (Hemiptera: Aphididae) and its association with the presence of the <span>A2666V</span> mutation Open
BACKGROUND Chemicals are widely used to protect field crops against aphid pests and aphid‐borne viral diseases. One such species is Myzus persicae (Sulzer), a global pest that attacks a broad array of agricultural crops and transmits many …
View article: P450 gene duplication and divergence led to the evolution of dual novel functions and insecticide cross-resistance in the brown planthopper Nilaparvata lugens
P450 gene duplication and divergence led to the evolution of dual novel functions and insecticide cross-resistance in the brown planthopper Nilaparvata lugens Open
The sustainable control of many highly damaging insect crop pests and disease vectors is threatened by the evolution of insecticide resistance. As a consequence, strategies have been developed that aim to prevent or delay resistance develo…
View article: Overexpression of UDP-glucuronosyltransferase and cytochrome P450 enzymes confers resistance to sulfoxaflor in field populations of the aphid, Myzus persicae
Overexpression of UDP-glucuronosyltransferase and cytochrome P450 enzymes confers resistance to sulfoxaflor in field populations of the aphid, Myzus persicae Open
The green peach aphid, Myzus persicae, is a highly damaging, globally distributed crop pest that has evolved multiple resistance to numerous insecticides. It is thus imperative that insecticides that are not strongly compromised by pre-exi…
View article: Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae
Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae Open
View article: Fly-Tox: A panel of transgenic flies expressing pest and pollinator cytochrome P450s
Fly-Tox: A panel of transgenic flies expressing pest and pollinator cytochrome P450s Open
There is an on-going need to develop new insecticides that are not compromised by resistance and that have improved environmental profiles. However, the cost of developing novel compounds has increased significantly over the last two decad…
View article: Host plant adaptation in the polyphagous whitefly, Trialeurodes vaporariorum, is associated with transcriptional plasticity and altered sensitivity to insecticides
Host plant adaptation in the polyphagous whitefly, Trialeurodes vaporariorum, is associated with transcriptional plasticity and altered sensitivity to insecticides Open
Background The glasshouse whitefly, Trialeurodes vaporariorum , is a damaging crop pest and an invasive generalist capable of feeding on a broad range of host plants. As such this species has evolved mechanisms to circumvent the wide spect…
View article: A flavin-dependent monooxgenase confers resistance to chlorantraniliprole in the diamondback moth, Plutella xylostella
A flavin-dependent monooxgenase confers resistance to chlorantraniliprole in the diamondback moth, Plutella xylostella Open
View article: MOESM18 of Host plant adaptation in the polyphagous whitefly, Trialeurodes vaporariorum, is associated with transcriptional plasticity and altered sensitivity to insecticides
MOESM18 of Host plant adaptation in the polyphagous whitefly, Trialeurodes vaporariorum, is associated with transcriptional plasticity and altered sensitivity to insecticides Open
Additional file 18: Tables S16-S21 Genes identified as differentially expressed between lines of T. vaporariorum reared on different host plants when compared to a line reared on French bean. Each comparison is shown in a separate tab. Tab…
View article: MOESM11 of Host plant adaptation in the polyphagous whitefly, Trialeurodes vaporariorum, is associated with transcriptional plasticity and altered sensitivity to insecticides
MOESM11 of Host plant adaptation in the polyphagous whitefly, Trialeurodes vaporariorum, is associated with transcriptional plasticity and altered sensitivity to insecticides Open
Additional file 11: Tables S9-S13. Identifier and sequences of curated T. vaporariorum genes belonging to detoxification enzyme families. Table S9 shows the P450 genes, Table S10 the carboxyl/cholinesterases, Table S11 the glutathione S-tr…
View article: Does host plant adaptation lead to pesticide resistance in generalist herbivores?
Does host plant adaptation lead to pesticide resistance in generalist herbivores? Open