Adam Reich
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View article: Is Cumulative Life Course Impairment Considered in Psoriasis Management? A Multinational Survey of People with Psoriasis and Healthcare Professionals
Is Cumulative Life Course Impairment Considered in Psoriasis Management? A Multinational Survey of People with Psoriasis and Healthcare Professionals Open
Misalignment exists in the experience of people living with psoriasis versus its assessment in clinical practice. Support is needed for assessment and monitoring of elements that may contribute to CLCI in clinical practice worldwide, to gu…
View article: The <scp>SWITCH</scp> algorithm: An expert consensus on treat‐to‐target criteria for chronic prurigo
The <span>SWITCH</span> algorithm: An expert consensus on treat‐to‐target criteria for chronic prurigo Open
Background To date, the management of chronic prurigo (CPG; prurigo nodularis) relies on expert consensus and guidelines without providing detailed recommendations on long‐term treatment management. Objectives This study was initiated by a…
View article: REZPEGALDESLEUKIN, NOVEL TREG-INDUCING THERAPY, DEMONSTRATES EFFICACY IN ATOPIC DERMATITIS AND ASTHMA IN PHASE 2B TRIAL
REZPEGALDESLEUKIN, NOVEL TREG-INDUCING THERAPY, DEMONSTRATES EFFICACY IN ATOPIC DERMATITIS AND ASTHMA IN PHASE 2B TRIAL Open
View article: Targeting IL-22RA1 with Temtokibart: A Novel Approach in Atopic Dermatitis: Phase 2a Monotherapy Study Results
Targeting IL-22RA1 with Temtokibart: A Novel Approach in Atopic Dermatitis: Phase 2a Monotherapy Study Results Open
This proof-of-concept study demonstrates that targeting the IL-22 pathway with temtokibart is clinically effective with a favorable safety profile.
View article: Benefits of a Compensating Dermocosmetic Routine as an Adjunct to Treatments in Patients With Mild to Very Severe Acne: Results From an Observational Multicenter Study
Benefits of a Compensating Dermocosmetic Routine as an Adjunct to Treatments in Patients With Mild to Very Severe Acne: Results From an Observational Multicenter Study Open
View article: Sexual Health in Patients with Atopic Dermatitis: A Cross-Sectional Study
Sexual Health in Patients with Atopic Dermatitis: A Cross-Sectional Study Open
Background and objectives: Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects not only physical health but also psychological well-being. While the emotional and social burden of AD is well documented, there is stil…
View article: Prurigo nodularis is a Th‐2‐mediated immune disease
Prurigo nodularis is a Th‐2‐mediated immune disease Open
View article: The Guardian Research Network: A Real‐World Data Source for Pharmacoepidemiologic Research and Regulatory Applications
The Guardian Research Network: A Real‐World Data Source for Pharmacoepidemiologic Research and Regulatory Applications Open
Background The quality of real‐world data (RWD) directly impacts the value of real‐world evidence (RWE) generated for regulatory decision‐making. Data owners and investigators must be prepared to provide documentation on data quality asses…
View article: Bullous subtype of rheumatoid neutrophilic dermatosis - An uncommon variant of a rare disease
Bullous subtype of rheumatoid neutrophilic dermatosis - An uncommon variant of a rare disease Open
View article: A Paradigm Shift in the Pathophysiology and Treatment of Chronic Kidney Disease–Associated Pruritus
A Paradigm Shift in the Pathophysiology and Treatment of Chronic Kidney Disease–Associated Pruritus Open
View article: Amlitelimab, an anti-OX40 ligand antibody, for atopic dermatitis: a plain language summary of STREAM-AD clinical study
Amlitelimab, an anti-OX40 ligand antibody, for atopic dermatitis: a plain language summary of STREAM-AD clinical study Open
View article: A multidisciplinary Delphi consensus on the modern definition of pruritus: Sensation and disease
A multidisciplinary Delphi consensus on the modern definition of pruritus: Sensation and disease Open
Background The definition of pruritus (synonym: itch) dates back to the 17th century and does not address the complexity of the sensation or the nature of pruritus as a disease. Objective Elaborate a new definition of pruritus comprising e…
View article: O13 Impact of amlitelimab (an anti-OX40 ligand antibody) on atopic dermatitis by body region: post hoc results from the STREAM-AD phase IIb study of moderate-to-severe atopic dermatitis
O13 Impact of amlitelimab (an anti-OX40 ligand antibody) on atopic dermatitis by body region: post hoc results from the STREAM-AD phase IIb study of moderate-to-severe atopic dermatitis Open
Amlitelimab is a fully human, nondepleting anti-OX40 ligand (OX40L) monoclonal antibody under investigation for atopic dermatitis (AD). Lesions on the head and neck are difficult to treat due to multiple triggers and generally have lower r…
View article: The Utility of Fourier Transform Infrared Spectroscopy (<scp>FTIR</scp>) for Detecting Exercise‐Induced Changes in the Human Hand Epidermis
The Utility of Fourier Transform Infrared Spectroscopy (<span>FTIR</span>) for Detecting Exercise‐Induced Changes in the Human Hand Epidermis Open
The literature lacks data on transient infrared spectral changes in the epidermis following physical exercise. This study tested the hypothesis that a single exercise session affects selected spectral bands (3270–1045 cm −1 ) in healthy in…
View article: 743 | ROLE OF CONSOLIDATION AFTER BRENTUXIMAB VEDOTIN TREATMENT IN RELAPSED/REFRACTORY MYCOSIS FUNGOIDES: POLISH LYMPHOMA RESEARCH GROUP RETROSPECTIVE MULTICENTER STUDY
743 | ROLE OF CONSOLIDATION AFTER BRENTUXIMAB VEDOTIN TREATMENT IN RELAPSED/REFRACTORY MYCOSIS FUNGOIDES: POLISH LYMPHOMA RESEARCH GROUP RETROSPECTIVE MULTICENTER STUDY Open
View article: Efficacy and safety of CT‐P39, an omalizumab biosimilar, in chronic spontaneous urticaria: 16‐week follow‐up study
Efficacy and safety of CT‐P39, an omalizumab biosimilar, in chronic spontaneous urticaria: 16‐week follow‐up study Open
Background A double‐blind, randomized Phase 3 study (NCT04426890) confirmed that CT‐P39 and European Union‐approved reference omalizumab (ref‐OMA) were comparable in terms of efficacy, quality of life (QoL), pharmacokinetics (PK), pharmaco…
View article: CONSTRUCT VALIDITY OF THE EQ-5D-5L IN CUTANEOUS LUPUS ERYTHEMATOSUS: A SECONDARY DATA ANALYSIS
CONSTRUCT VALIDITY OF THE EQ-5D-5L IN CUTANEOUS LUPUS ERYTHEMATOSUS: A SECONDARY DATA ANALYSIS Open
PV067 / #449 Poster Topic: AS07 - Cutaneous Lupus Background/Purpose Cutaneous lupus erythematosus (CLE) significantly impacts health-related quality of life (HRQoL). Although the EuroQol 5 Dimensions 5 Levels (EQ-5D-5L) is a widely used H…
View article: A practical algorithm for the treatment of mild-to-moderate atopic dermatitis (AD) in pediatric patients in Europe: expert recommendations
A practical algorithm for the treatment of mild-to-moderate atopic dermatitis (AD) in pediatric patients in Europe: expert recommendations Open
In this article, we propose an algorithm for a TCS-sparing treatment strategy, focusing on topical calcineurin inhibitors for the management of mild-to-moderate AD in infants and children, including AD of sensitive skin areas. This algorit…
View article: Polarized Dermoscopy and Ultraviolet-Induced Fluorescence Dermoscopy of Basal Cell Carcinomas in the H- and Non-H-Zones of the Head and Neck
Polarized Dermoscopy and Ultraviolet-Induced Fluorescence Dermoscopy of Basal Cell Carcinomas in the H- and Non-H-Zones of the Head and Neck Open
View article: Inflammation-Related Markers in Pediatric Psoriasis: Resistin as a Potential Marker of Psoriasis Severity
Inflammation-Related Markers in Pediatric Psoriasis: Resistin as a Potential Marker of Psoriasis Severity Open
Background/Objective: Psoriasis is a chronic inflammatory skin disease. Studies on adult population have confirmed that there is an association between psoriasis and metabolic as well as cardiovascular diseases. The aim of this study was t…
View article: Does Skin Color Matter in Psoriasis?
Does Skin Color Matter in Psoriasis? Open
View article: IL-36–driven pustulosis: Transcriptomic signatures match between generalized pustular psoriasis (GPP) and acute generalized exanthematous pustulosis (AGEP)
IL-36–driven pustulosis: Transcriptomic signatures match between generalized pustular psoriasis (GPP) and acute generalized exanthematous pustulosis (AGEP) Open
We propose that AGEP is a drug-induced variant of GPP and therefore part of IL-36-related pustulosis. A key signature overarching this spectrum was identified, thereby opening the therapeutic approach of IL-36 inhibition to all subtypes of…
View article: Global Delphi consensus on treatment goals for generalized pustular psoriasis
Global Delphi consensus on treatment goals for generalized pustular psoriasis Open
Background Generalized pustular psoriasis (GPP) is a chronic, systemic, neutrophilic inflammatory disease. A previous Delphi panel established areas of consensus on GPP, although patient perspectives were not included and aspects of treatm…
View article: <scp>CT</scp>‐<scp>P39</scp> Compared With Reference Omalizumab in Chronic Spontaneous Urticaria: Results From a Double‐Blind, Randomized, Active‐Controlled, Phase 3 Study
<span>CT</span>‐<span>P39</span> Compared With Reference Omalizumab in Chronic Spontaneous Urticaria: Results From a Double‐Blind, Randomized, Active‐Controlled, Phase 3 Study Open
Background This study compared the therapeutic equivalence of CT‐P39 (an omalizumab biosimilar) and EU‐approved reference omalizumab (ref‐OMA) in patients with chronic spontaneous urticaria. Methods This double‐blind, randomized, active‐co…
View article: Application of Ultraviolet-Induced Fluorescence Trichoscopy (UVFT) in Hair and Scalp Diseases
Application of Ultraviolet-Induced Fluorescence Trichoscopy (UVFT) in Hair and Scalp Diseases Open
UVFT supports the differentiation between scarring and non-scarring alopecia, as well as between psoriasis and seborrheic dermatitis. UVFT may hypothetically facilitate the biopsy site selection by highlighting the subclinical perifollicul…
View article: Integrin α1 (ITGA1) is a novel biomarker of melanoma cells subjected to chemotherapy-induced senescence
Integrin α1 (ITGA1) is a novel biomarker of melanoma cells subjected to chemotherapy-induced senescence Open
View article: Referee report. For: Associations Between Factors Affecting Itching and Quality of Life in Thai Patients with Psoriasis: A Cross-Sectional Study [version 2; peer review: 2 approved, 1 approved with reservations]
Referee report. For: Associations Between Factors Affecting Itching and Quality of Life in Thai Patients with Psoriasis: A Cross-Sectional Study [version 2; peer review: 2 approved, 1 approved with reservations] Open
View article: Psoriasis in the paediatric population: assessmentof comorbidities, risk factors of their occurrence, qualityof life of patients and therapy implemented
Psoriasis in the paediatric population: assessmentof comorbidities, risk factors of their occurrence, qualityof life of patients and therapy implemented Open
Psoriatic children and adolescents are often obese and with abnormal lipid profile, which may constitute a risk factor of cardiovascular diseases. Psoriasis has a negative impact on the quality of life of patients and their families.
View article: Clinical Utility of Various Formulations of Calcipotriene and Betamethasone Dipropionate for the Treatment of Plaque Psoriasis in Patients Aged 12 Years or Older
Clinical Utility of Various Formulations of Calcipotriene and Betamethasone Dipropionate for the Treatment of Plaque Psoriasis in Patients Aged 12 Years or Older Open
Plaque-type psoriasis is a chronic immune-mediated inflammatory skin disease of uncertain etiology, significantly impacting patient well-being. This chronic condition not only contributes to stigmatization and mental health challenges but …
View article: Characteristics of Patients with Generalized Pustular Psoriasis: A Report of the Polish Generalized Pustular Psoriasis Group
Characteristics of Patients with Generalized Pustular Psoriasis: A Report of the Polish Generalized Pustular Psoriasis Group Open